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Elsevier

Mass Spectrometry

Techniques for Structural Characterization of Glycans

  • 1st Edition - May 6, 2016
  • Latest edition
  • Author: Michael A. Madson
  • Language: English

Mass Spectrometry: Techniques for the Structural Characterization of Glycans presents new methods for conducting detailed carbohydrate qualitative analysis—arming analytica… Read more

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Description

Mass Spectrometry: Techniques for the Structural Characterization of Glycans presents new methods for conducting detailed carbohydrate qualitative analysis—arming analytical chemists, pharmaceutical scientists, and food scientists with a quick reference that will allow them to determine the structures of carbohydrates molecules.

As there is a need in the scientific community for content specific to structural determination and analysis of new glycoprotein drug, and because structure-activity analysis requires a structural determination of the N- and O-linked oligosaccharides linked to glycol-proteins, this book provides the relevant research that are necessary for advances and new outcomes in this area of study.

Key features

  • Authored by an analytical chemist with more than 30 years of experience in research and industry
  • Serves as a quick reference in mass spectral analysis and carbohydrates
  • Includes more than 60 figures to aid in the retention of key concepts

Readership

Analytical chemists, pharmaceutical scientists, and food scientists conducting research in mass spectral analysis.

Table of contents

  • Dedication
  • Mass Spectral Analysis of Carbohydrates
    • Abstract
    • 1 Isolation Methods for MS Analysis
    • 2 Component Monosaccharide Analysis by Acid Catalyzed Hydrolysis of Glycan and Qualitative Chromatographic Identification by HPLC
    • 3 Identification of Glycoses Versus Glycitols by HPAEC-PAD Difference Chromatograms
    • 4 The Methods for Preparing an Oligosaccharide Reducing Glycan from a Glycoprotein, Linked Through O-Glycosidic Linkage
    • Conclusions
    • References

Product details

  • Edition: 1
  • Latest edition
  • Published: May 6, 2016
  • Language: English

About the author

MM

Michael A. Madson

Mike Madson is CEO and Senior Research Scientist of BioLogistics, LLC, Iowa, USA
Affiliations and expertise
BioLogistics, LLC, Iowa, USA

View book on ScienceDirect

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