Management of Melanoma of the Head and Neck, An Issue of Oral and Maxillofacial Surgery Clinics of North America

1st Edition, Volume 34-2 - May 3, 2022
Editor: Al Haitham Al Shetawi
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 4 9 9 5 - 1
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 4 9 9 6 - 8

In this issue of Oral and Maxillofacial Surgery Clinics, guest editor Dr. Al Haitham Al Shetawi brings his considerable expertise to the topic of Management of Melanoma in the He… Read more

Management of Melanoma of the Head and Neck, An Issue of Oral and Maxillofacial Surgery Clinics of North America

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In this issue of Oral and Maxillofacial Surgery Clinics, guest editor Dr. Al Haitham Al Shetawi brings his considerable expertise to the topic of Management of Melanoma in the Head and Neck. Top experts in the field cover key topics such as reconstruction of melanoma defects, management of mucosal melanoma, adjuvant therapies in melanoma, future treatments in melanoma, and more.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
Introduction to Head and Neck Melanoma: A Dermatologist's Perspective
Key points
Introduction
Identification, evaluation, and management of melanoma
Subtypes of melanoma
Superficial spreading melanoma
Nodular melanoma
Lentigo maligna melanoma
Guidelines of care of primary cutaneous (head and neck) melanoma
Multidisciplinary approach to melanoma management
Clinics care points
Classification and Staging of Melanoma in the Head and Neck
Key points
Introduction
Melanoma subtypes and classification
Genetic characterization of melanoma
Clinical classification and staging
Primary tumor staging
Breslow thickness
Ulceration
Mitotic rate
Clark level of invasion
Staging of regional lymph nodes
Distant metastasis
The role of imaging for stage determination
Prognostic stage group
Clinical staging
Pathologic staging (pTNM)
Melanoma-specific survival rates
Summary
Imaging and Laboratory Workup for Melanoma
Key points
Introduction
Imaging
Laboratory testing
Summary
Clinics care points
Principles of Surgery in Head and Neck Cutaneous Melanoma
Key points
Introduction
Historical perspective
Early stage melanoma
Surgical biopsy techniques and merits
Primary melanoma excision—wide local excision
Critical points in margin evaluation
Sentinel lymph node biopsy
Controversies
Surgical guidelines for head and neck melanoma management
Mucosal melanoma of the head and neck
Summary
Clinics care points
Mohs Micrographic Surgery for the Treatment of Cutaneous Melanomas of the Head and Neck
Key points
Introduction
Summary
Clinics care points
Management of Regional Lymph Nodes in Head and Neck Melanoma
Key points
Introduction
Risk factors for lymph node metastases in head and neck melanoma
Sentinel lymph node biopsy for head and neck melanoma
Neck dissection for head and neck melanoma
Unknown primary melanoma
Radiotherapy use in head and neck melanoma
Immunotherapy in head and neck melanoma
Summary/Discussion
Clinics care points
Reconstruction of Head and Neck Melanoma Defects
Key points
Introduction
Pivotal flaps
Advancement flaps
Hinge flaps
Defects of the scalp
Defects of the forehead
Defects of the cheek
Defects of the nose
Defects of the auricle
Defects of the neck
Summary/discussion
Clinics care points
Management of Head and Neck Mucosal Melanoma
Key points
Introduction
Cause and epidemiology
Biological characteristics and molecular biology
Pathology and pathways of spread
Clinical manifestations
Patient evaluation and staging
Primary treatment
Advanced disease and palliation
Prognosis and follow-up
Summary and future perspectives
Clinics care points
Adjuvant and Neoadjuvant Therapies in Cutaneous Melanoma
Key points
Staging and immunogenomic profiling
Background: Systemic therapies for cutaneous metastatic melanoma
Adjuvant therapy
Neoadjvuant therapy
Clinics care points
Future Treatments in Melanoma
Key points
Introduction
Gene expression profiling
Treatment for high-risk resected local disease
Neoadjuvant therapy
Antiangiogenic therapy
Intralesional therapy
Vaccine for melanoma
Summary/Discussion
Clinics care points

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Management of Melanoma of the Head and Neck, An Issue of Oral and Maxillofacial Surgery Clinics of North America

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Al Haitham Al Shetawi