Mammalian Cell Membranes

Contributors

Preface


1 The Organization of the Plasma Membrane of Mammalian Cells: Structure in Relation to Function


1.1 Introduction


1.2 Chemical Composition and Membrane Architecture


1.3 Lipid Fluidity and Membrane Function


1.4 Some Consequences of Translateral Movement


1.5 A Special Class of Proteins: Transplantation Antigens


1.6 Regional Specialization of the Cell Surface Membrane


1.7 Regulatory Molecules (Hormones, Mitogens and Natural Growth Factors) Interacting with the Cell Surface


1.8 Cell Contact and Growth Control


2 Membrane of the Endoplasmic Reticulum and the Secretary System and their Role in Plasma Membrane Regulation


2.1 Introduction


2.2 Membranes of the Endoplasmic Reticulum


2.3 Membranes of the Secretory System


2.4 Withdrawal of Membrane from the Plasma Membrane and its Consequences


2.5 Final Note


3 Membranes of the Golgi Apparatus


3.1 Morphology


3.2 Chemical Composition


3.3 Functional Roles of Golgi Membranes


3.4 Biogenesis of Golgi Membranes


4 The Structure of Mitochondrial Membranes


4.1 Introduction


4.2 The Mitochondrial Outer Membrane


4.3 The Mitochondrial Inner Membrane


5 Lysosomal Membranes


5.1 Introduction


5.2 Stability of the Lysosomal Membrane


5.3 Permeability of the Lysosomal Lembrane in Vitro


5.4 Permeability of the Lysosomal Membrane in the Cell


5.5 Permeability of the Lysosomal Membrane and Function of Lysosomes


5.6 Origin of the Lysosomal Membrane


5.7 Chemical and Enzymatic Composition of the Lysosomal Membrane


6 Microbody Membranes


6.1 General Properties of the Organelle


6.2 Microbody Enzymes


6.3 The Membrane


6.4 Membrane Enzyme Components


6.5 Lipid Composition


6.6 Permeability


6.7 Shuttles of Metabolites


6.8 Movement of Protein Across Microbody Membranes


6.9 Comparison of the Microbody Membrane with Other Membranes


7 The Nuclear Envelope in Mammalian Cells


7.1 Introduction


7.2 Structure of the Nuclear Envelope


7.3 Composition of the Nuclear Envelope


7.4 The nuclear Envelope During Cell Division and the Cell Cycle


7.5 Nucleo-Cytoplasmic Exchanges


7.6 Role of the Nuclear Envelope in Cellular Organization


7.7 Summary


8 Myelin


8.1 Definition


8.2 Molecular Organization


8.3 Myelin Formation


8.4 Chemical Composition


8.5 Metabolic Aspects of Myelin


8.6 Defective Myelination


8.7 Variations in Myelination


8.8 Regeneration of the Myelin Sheath


9 Basement Membranes


9.1 Introduction


9.2 Preparation of Basement Membranes


9.3 Solubility Studies


9.4 Chemical Characterization


9.5 Nature of the Structural Components


9.6 Immunochemical Properties


9.7 Biosynthesis of Basement Membranes


9.8 Conclusions


10 Microvilli and Cilia: Surface Specializations of Mammalian Cells


10.1 Introduction


10.2 Microvilli


10.3 Ruffles and Blebs


10.4 Cilia

Index