Limited Offer
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Liver Transplantation and Transplantation Oncology, An Issue of Surgical Clinics
- 1st Edition, Volume 104-1 - November 14, 2023
- Editor: Shimul Shah
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 2 9 8 7 - 2
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 2 9 8 8 - 9
In this issue of Surgical Clinics, guest editor Dr. Shimul Shah brings his considerable expertise to the topic of Liver Transplantation and Transplantation Oncology. Top experts i… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteIn this issue of Surgical Clinics, guest editor Dr. Shimul Shah brings his considerable expertise to the topic of Liver Transplantation and Transplantation Oncology. Top experts in the field review the current status of liver transplantation in North America, outcomes involving living versus deceased donors, transplants for different liver diseases, machine perfusion, and immunotherapy.
- Contains 16 relevant, practice-oriented topics including outcomes of living donor liver transplantation compared to deceased donor liver transplantation; living donor liver transplantation: left lobe or right lobe; current status of liver transplantation in North America; current use of immunosuppression in liver transplantation; expanding the boundaries for liver transplantation for hepatocellular carcinoma; and more.
- Provides in-depth clinical reviews on liver transplantation and transplantation oncology, offering actionable insights for clinical practice.
- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Transplant surgeons
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Foreword
- Preface
- Current Status of Liver Transplantation in North America
- Key points
- Introduction
- Donor characteristics
- Liver recipients characteristics
- Waiting list outcomes
- The rise of transplant oncology
- Living donor liver transplant
- Machine perfusion
- Clinics care points
- Current Use of Immunosuppression in Liver Transplantation
- Key points
- Introduction
- Induction therapy in liver transplantation
- Maintenance therapy in liver transplantation
- Dual (calcineurin + antimetabolite) therapy maintenance immunosuppression
- Belatacept in liver transplant
- Withdrawal of immunosuppression
- Pregnancy and immunosuppression in liver transplant
- Agents for antibody-mediated rejection in liver transplantation
- Summary
- Clinics care points
- Disclosure
- Donation After Circulatory Death Liver Transplantation: Early Challenges, Clinical Improvement, and Future Directions
- Key points
- Introduction
- Early experience: clinical outcomes
- Modern approach
- Recent experience: clinical outcomes and donation after circulatory death utilization
- Liver perfusion and future directions
- Summary
- Clinics care points
- Disclosure
- Role of Machine Perfusion in Liver Transplantation
- Key points
- Introduction
- Machine perfusion
- The future of machine perfusion: Conclusion
- Clinics care points
- Funding
- Donor Viral Hepatitis and Liver Transplantation
- Key points
- Introduction
- The history: Hepatitis C virus
- The first step: Utilization of hepatitis C virus (+) donors in hepatitis C virus(+) recipients
- The culture shift: Utilization of hepatitis C virus(+) allografts in hepatitis C virus(−) recipients
- The future of hepatitis C virus liver transplantation
- Current hepatitis C virus treatment strategies
- Hepatitis B virus
- Hepatitis B core antibody liver transplantation:
- Hepatitis B surface antigen liver transplantation
- Hepatitis B virus nucleic acid amplification testing positive allografts
- Current hepatitis B virus treatment strategies
- Summary
- Clinics care points
- Disclosure
- Outcomes of Living Donor Liver Transplantation Compared with Deceased Donor Liver Transplantation
- Key points
- Introduction
- Summary
- Clinics care points
- Conflict of interest disclosures
- Living Donor Liver Transplantation: Left Lobe or Right Lobe
- Key points
- Introduction
- Donor evaluation
- Graft selection
- Anatomic considerations
- Recipient considerations: right versus left
- Outcomes
- Summary
- Clinics care points
- Disclosure
- Transplantation for Hepatocellular Carcinoma
- Key points
- Introduction/Background
- History/Epidemiology
- Clinics care points
- Funding
- Resection Versus Transplant for Hepatocellular Carcinoma: How to Offer the Best Modality
- Key points
- Introduction
- Risk of surgical resection
- Risk of recurrence
- Summary
- Clinics care points
- Disclosure
- Expanding the Boundaries for Liver Transplantation for Hepatocellular Carcinoma
- Key points
- Introduction
- Patient evaluation overview
- Liver transplantation in the management of hepatocellular carcinoma
- Tumor downstaging using local-regional therapies
- New developments
- Summary
- Clinics care points
- Disclosure
- Downstaging Techniques for Hepatocellular Carcinoma in Candidates Awaiting Liver Transplantation
- Key points
- Introduction
- Patient evaluation
- Surgical and interventional treatment options for downstaging
- Systemic treatment options
- Combination therapies
- Evaluation of overall outcomes
- Summary
- Clinics care points
- Disclosure
- Immunotherapy and Liver Transplantation: The Future or the Failure?
- Key points
- Introduction
- Neoadjuvant immunotherapy rationale
- Ongoing trials in neoadjuvant immunotherapy in hepatocellular carcinoma
- Immunotherapy pre-liver transplantation
- Immunotherapy post-liver transplant and its associated hepatotoxicity
- Summary
- Clinics care points
- Liver Transplantation for Hilar Cholangiocarcinoma
- Key points
- Epidemiology and risk factors
- Diagnosis and staging
- Selection for liver transplantation for hilar cholangiocarcinoma
- Neoadjuvant protocols
- Treatment dropout
- Technical details
- Postoperative care and complications
- Oncologic outcomes
- Clinics care points
- How to Determine Unresectability in Hilar Cholangiocarcinoma
- Key points
- Background
- Staging and considerations for resection
- Preoperative assessment
- Intraoperative assessment
- Treatment options in the event of unresectability
- Summary
- Clinics care points
- Liver Transplant for Intrahepatic Cholangiocarcinoma
- Key points
- Introduction
- Diagnosis
- Surgical management of intrahepatic cholangiocarcinoma
- Liver resection
- Liver transplantation
- Clinical trials in liver transplant for intrahepatic cholangiocarcinoma: future trends
- Challenges of liver transplant for intrahepatic cholangiocarcinoma
- Clinics care points
- Disclosure
- Liver Transplantation for Colorectal Liver Metastases
- Key points
- Introduction
- Current guidelines for management of metastatic colorectal cancer
- Alternative treatment approaches
- Liver transplantation
- Modern era of liver transplantation for colorectal liver metastases
- Limitations to liver transplantation for colorectal liver metastases
- Recurrence after liver resection versus transplantation
- Summary
- Clinics care points
- Disclosure
- No. of pages: 240
- Language: English
- Edition: 1
- Volume: 104-1
- Published: November 14, 2023
- Imprint: Elsevier
- Hardback ISBN: 9780443129872
- eBook ISBN: 9780443129889
SS
Shimul Shah
Affiliations and expertise
Professor; Division Chief of Transplantation, Vice Chair for Health Services Research, James and Catherine Orr Endowed Chair of Liver Transplantation Surgery, University of Cincinnati College of Medicine