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Linne & Ringsrud's Clinical Laboratory Science
Concepts, Procedures, and Clinical Applications
- 8th Edition - December 22, 2018
- Author: Mary Louise Turgeon
- Language: English
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 5 4 9 8 3 - 7
Thoroughly updated and easy-to-follow, Linne & Ringsrud's Clinical Laboratory Science: Concepts, Procedures, and Clinical Applications, 8th Edition offers a fundament… Read more
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Request a sales quoteThoroughly updated and easy-to-follow, Linne & Ringsrud's Clinical Laboratory Science: Concepts, Procedures, and Clinical Applications, 8th Edition offers a fundamental overview of the laboratory skills and techniques you’ll need for success in the clinical laboratory. Author Mary Louise Turgeon's simple and straightforward writing clarifies complex concepts, and her unique discipline-by-discipline approach helps you build knowledge and learn to confidently perform routine clinical laboratory tests with accurate, effective results. Topics like safety, measurement techniques, and quality assessment are woven throughout the various skills. The new eighth edition also features updated content including expanded information on viruses and automation. It’s the must-have foundation for anyone wanting to pursue a profession in the clinical lab.
- Broad content scope provides an ideal introduction to clinical laboratory science at a variety of levels, including CLS/MT, CLT/MLT, and Medical Assisting.
- Case studies include critical thinking and multiple-choice questions to challenge readers to apply the content to real-life scenarios.
- Expert insight from respected educator Mary Lou Turgeon reflects the full spectrum of clinical lab science.
- Detailed procedures guides readers through the exact steps performed in the lab.
- Vivid full-color illustrations familiarize readers with what they’ll see under the microscope.
- Review questions at the end of each chapter help readers assess your understanding and identify areas requiring additional study.
- Evolve companion website provides convenient online access to all of the procedures in the text and houses animations, flashcards, and additional review questions not found in the printed text.
- Procedure worksheets can be used in the lab and for assignment as homework.
- Streamlined approach makes must-know concepts and practices more accessible.
- Convenient glossary simplifies the process of looking up definitions without having to search through each chapter.
- Cover image
- Title page
- Table of Contents
- Copyright
- About the Author
- Reviewers
- Dedication
- Preface
- What’s new in the eighth edition of clinical laboratory science?
- Ways to use this book
- Acknowledgments
- Part I: Basic Laboratory Techniques
- 1: Fundamentals of the Clinical Laboratory
- Clinical laboratory science
- Clinical laboratory science as a profession
- Clinical laboratory overview
- Clinical laboratory improvement amendments (CLIA) of 1988
- Laboratory departments
- Health care organizations
- Primary accrediting organizations
- External government laboratory accreditation and regulation
- Alternate sites of testing
- Medical-legal issues
- Medical ethics
- Case studies
- Review questions (Answers in Appendix A)
- Clinical Laboratory Science
- Overview of the Clinical Laboratory
- Clinical Laboratory Improvement Amendments (CLIA) of 1988
- Laboratory Departments
- Health Care Organizations
- Primary Accrediting Organizations
- External Government Laboratory Accreditation and Regulation
- Alternate Sites of Testing
- Medical-Legal Issues
- Medical Ethics
- 2: Safety: Patient and Clinical Laboratory Practices
- Patient safety
- Safety standards and governing agencies
- Avoiding transmission of infectious diseases
- Bloodborne pathogens
- Safe work practices for infection control
- Specimen handling and shipping requirements
- Prevention of disease transmission
- Additional laboratory hazards
- Final decontamination of waste materials
- Safety audit
- Basic first-aid procedures
- Case study
- Case Study 2.1 Multiple Choice Questions (Answers in Appendix A)
- Critical Thinking Group Discussion Questions
- Review questions (Answers in Appendix A)
- Patient Safety
- Safety Standards and Governing Agencies
- Avoiding Transmission of Infectious Diseases
- Bloodborne Pathogens
- Safe Work Practices for Infection Control
- Specimen Handling and Shipping Requirements
- Prevention of Disease Transmission
- Additional Laboratory Hazards
- Final Decontamination of Waste Materials
- Safety audit
- Basic first-aid procedures
- Bonus Challenge Questions
- 3: Quality Assessment and Quality Control in the Clinical Laboratory
- The value of quality
- Patient specimens
- Clinical laboratory improvement amendments
- Voluntary accrediting organizations
- ISO 15189 standards in clinical laboratories
- Lean and six sigma
- Quality assessment
- Quality assessment—error analysis
- Quality assessment—phases of testing
- Proficiency testing (PT)
- Alternate assessment
- Accuracy in reporting results and documentation
- Quality control
- Control specimens
- Quality assessment descriptors
- Quality control statistics
- Total analytic error
- Monitoring quality control
- Other QC rules
- Testing outcomes
- Case study
- Review Questions (Answers in Appendix A)
- The Value of Quality
- Patient Specimens
- Clinical Laboratory Improvement Amendments
- Voluntary Accrediting Organizations
- ISO 15189 Standards in Clinical Laboratories
- Lean and Six Sigma
- Quality Assessment
- Quality—Error Analysis
- Quality Assessment—Phases of Testing
- Proficiency Testing
- Alternate Assessment
- Accuracy in Reporting Results and Documentation
- Quality Control
- Control Specimens
- Quality Assessment Descriptors
- Quality Control Statistics
- Total Analytical Error
- Monitoring Quality Control
- Other QC Rules
- Testing Outcomes
- 4: Phlebotomy: Collecting and Processing Patient Blood Specimens
- Quality assessment
- Infection control
- Specimen collection
- Venous blood collection (phlebotomy)
- Specimens: general preparation
- Capillary or peripheral blood collection by skin puncture
- Capillary blood collection
- Case studies
- Review Questions (Answers in Appendix A)
- Quality Assessment
- Infection Control
- Specimen Collection
- Venous Blood Collection (Phlebotomy)
- Specimens: General Preparation
- Capillary or Peripheral Blood Collection
- 5: The Microscope
- Description
- Parts of the microscope
- Care and cleaning of the microscope
- Use of the microscope
- Other types of microscopes (Illumination systems)
- Digital microscopy
- Review Questions (Answers in Appendix A)
- Description
- Parts of the Microscope
- Care and Cleaning of the Microscope
- Use of the Microscope
- Other Types of Microscopes (Illumination Systems)
- Digital Microscopy and Workflow
- 6: Systems of Measurement, Laboratory Equipment, and Reagents
- Systems of measurement
- International System (SI System)
- Labware
- Laboratory balances
- Laboratory centrifuges
- Laboratory reagent water
- Reagents used in laboratory assays
- Review Questions (Answers in Appendix A)
- Systems of Measurement
- International System (SI System)
- Labware
- Laboratory Balances
- Laboratory Centrifuges
- Laboratory Reagent Water
- Reagents Used in Laboratory Assays
- 7: Laboratory Mathematics and Solution Preparation
- Significant figures
- Exponents
- Density and specific gravity
- Expressions of solution concentration
- Dilutions
- Review Questions (Answers in Appendix A)
- Significant Figures
- Exponents
- Density and Specific Gravity
- Expressions of Solution Concentration
- Dilutions
- 8: Basic and Contemporary Techniques in the Clinical Laboratory
- Photometry
- Absorbance spectrophotometry
- Reflectance spectrophotometry
- Nephelometry
- Flow (cell) cytometry
- Immunoassays
- Alternative labeling technologies
- Chemiluminescence
- Chromatography and Immunochromatography
- Molecular diagnostic techniques
- Electrochemical methods
- Review Questions (Answers in Appendix A)
- Photometry
- Absorbance Spectrophotometry
- Reflectance Spectrophotometry
- Nephelometry
- Flow (Cell) Cytometry
- Immunoassays
- Alternative Labeling Technologies
- Chemiluminescence
- Chromatography and Immunochromatography
- Molecular Diagnostic Techniques
- Electrochemical Methods
- Chromatography
- 9: Laboratory Testing: From Point of Care to Total Automation
- Point-of-care testing
- Non–instrument-based point-of-care testing
- Handheld POCT Equipment
- Emerging patient-centric technologies
- Overview of informatics
- Communication and network devices
- Computer applications
- Overview of automation
- Case study
- Review Questions (Answers in Appendix A)
- Point-of-Care Testing
- Non–Instrument-Based Point-of-Care Testing
- Handheld POCT Equipment
- Emerging Patient-Centric Technologies
- Overview of Informatics
- Communication and Network Devices
- Computer Applications
- Overview of Automation
- Part II: Basic Clinical Laboratory Specializations
- 10: Introduction to the Principles and Practice of Clinical Chemistry
- Glucose and glucose metabolism
- Diabetes
- Electrolytes
- Acid-base balance and blood gases
- Renal function
- Uric acid
- Lipids
- Cardiovascular disease
- Liver and pancreatic testing
- Hormone assays
- Tumor markers
- Therapeutic drug monitoring
- Drugs of abuse
- Automation in clinical chemistry
- Case studies
- Review Questions (Answers in Appendix A)
- Glucose and Glucose Metabolism
- Diabetes
- Electrolytes
- Acid-Base Balance and Blood Gases
- Renal Function
- Uric Acid
- Lipids
- Cardiovascular Disease
- Liver and Pancreatic Testing
- Hormone Assays
- Tumor Markers
- Therapeutic Drug Monitoring
- Drugs of Abuse
- Automation in Clinical Chemistry
- 11: An Introduction to the Principles and Practice of Clinical Hematology
- Hematopoiesis: overall blood cell maturation and function
- Erythrocytes
- Leukocytes
- Lymphocyte maturation and function
- Thrombocytes
- Clinical hematology procedures
- Additional hematology procedures
- Red blood cell indices
- Microscopic examination of the peripheral blood film
- Case studies
- Review Questions (Answers in Appendix A)
- Hematopoiesis: Overall Blood Cell Maturation and Function
- Erythrocytes
- Leukocytes
- Lymphocyte Maturation and Function
- Thrombocytes
- Clinical Hematology Procedures
- Additional Hematology Procedures
- Red Blood Cell Indices
- Microscopic Examination of the Peripheral Blood Film
- 12: Hemostasis and Blood Coagulation
- Hemostatic mechanism
- Quantitative platelet disorders
- Qualitative platelet disorders
- Coagulation
- Pathways for coagulation cascade
- Fibrinolysis
- Protective mechanisms against thrombosis
- Tests for hemostasis and coagulation
- Case studies
- Review Questions (Answers in Appendix A)
- Hemostatic Mechanism
- Quantitative Platelet Disorders
- Qualitative Platelet Disorders
- Coagulation
- Pathways for Coagulation Cascade
- Fibrinolysis
- Protective Mechanisms Against Thrombosis
- Tests for Hemostasis and Coagulation
- 13: Renal Physiology and Urinalysis
- Overview of urinalysis
- Renal anatomy and physiology
- Composition of urine
- Collection and preservation of urine specimens
- Physical properties of urine
- Chemical tests in routine urinalysis
- Microscopic analysis of urine sediment
- Constituents of urine sediment
- Automation in Urinalysis
- Case studies
- Review Questions (Answers in Appendix A)
- Overview of Urinalysis
- Renal Anatomy and Physiology
- Composition of Urine
- Collection and Preservation of Urine Specimens
- Physical Properties of Urine
- Chemical Tests in Routine Urinalysis
- Microscopic Analysis of Urine Sediment
- Constituents of Urine Sediment
- Automation in Urinalysis
- 14: Examination of Body Fluids and Miscellaneous Specimens
- Overview of Body Fluids
- Cerebrospinal Fluid
- Serous Fluids: Pericardial, Pleural, and Peritoneal
- Synovial Fluid
- Seminal Fluid
- Amniotic Fluid
- Saliva
- Automation in Body Fluid Analysis
- Case studies
- Review Questions (Answers in Appendix A)
- Overview of Body Fluids
- Cerebrospinal Fluid
- Serous Fluids: Pericardial, Pleural, and Peritoneal
- Synovial Fluid
- Seminal Fluid
- Amniotic Fluid
- Saliva
- Automation in Body Fluid Analysis
- 15: Introduction to Medical Microbiology
- Introduction to Microorganisms
- Classification of Microorganisms: Taxonomy
- Protection of Laboratory Personnel and Good Laboratory Practices
- Specimens for Microbiological Examination
- Basic Equipment and Techniques Used in Microbiology
- Identification of Bacteria
- Urine Cultures
- Throat Cultures
- Genitourinary Cultures
- Enteric Disease
- Blood Cultures
- Wound or Soft Tissue Cultures
- Bacterial Disease
- Quality Control in the Microbiology Laboratory
- Mycobacteria
- Tests for Fungi (Mycology)
- Tests for Parasites (Parasitology)
- Tests for Viruses (Virology)
- Automation
- Case studies
- Review Questions (Answers in Appendix A)
- Introduction to Microorganisms
- Classification of Microorganisms: Taxonomy
- Protection of Laboratory Personnel and Good Laboratory Practices
- Specimens for Microbiological Examination
- Basic Equipment and Techniques Used in Microbiology
- Identification of Bacteria
- Urine Cultures
- Throat Cultures
- Genitourinary Cultures
- Enteric Disease
- Blood Cultures
- Wound or Soft Tissue Cultures
- Bacterial Disease
- Quality Control in the Microbiology Laboratory
- Mycobacteria
- Tests for Fungi (Mycology)
- Tests for Parasites (Parasitology)
- Tests for Viruses (Virology)
- Automation
- 16: Immunology and Serology
- Overview of Immunology and Serology
- Antigens and Antibodies
- Complement
- Body Defenses Against Microbial Disease
- Hypersensitivity
- Types of Antigens and Reactions
- Cells and Cellular Activities of the Immune System
- Immunologic Disorders
- Principles of Immunologic and Serologic Methods
- Specimens for Serology and Immunology
- Immunologic and Serologic Testing for Bacterial and Viral Diseases
- Autoimmune Disorders
- Case studies
- Review Questions (Answers in Appendix A)
- Overview of Immunology and Serology
- Antigens and Antibodies
- Complement
- Body Defenses Against Microbial Disease
- Hypersensitivity
- Types of Antigens and Reactions
- Cells and Cellular Activities of the Immune System
- Immunologic Disorders
- Principles of Immunologic and Serologic Methods
- Specimens for Serology and Immunology
- Immunologic and Serologic Testing for Bacterial and Viral Disease
- Autoimmune Disorders
- 17: Immunohematology and Transfusion Medicine
- Overview of blood banking
- Benefits and reasons for transfusion
- Whole blood, blood components, and derivatives for transfusion
- Blood donation: donors, collection, storage, and processing
- Other Types of Blood Donations
- Antigens and Antibodies in Immunohematology
- ABO red blood cell group system
- Rh red blood cell group system
- Other blood group systems
- Antihuman globulin reaction
- Compatibility testing and crossmatching
- Adverse Effects of Transfusion
- Hemolytic Disease of the Fetus and Newborn
- Automated Testing Technology and Systems
- Case studies
- Review Questions (Answers in Appendix A)
- Overview of Blood Banking
- Benefits and Reasons for Transfusion
- Whole Blood, Blood Components, and Derivatives for Transfusion
- Blood Donation: Donors, Collection, Storage, and Processing
- Other Types of Blood Donations
- Antigens and Antibodies in Immunohematology
- ABO Red Blood Cell Group System
- Rh Red Blood Cell Group System
- Other Blood Group Systems
- Antihuman Globulin Reaction
- Compatibility Testing and Crossmatching
- Adverse Effects of Transfusion
- Hemolytic Disease of the Fetus and Newborn
- Automated Testing Technology and Systems
- Appendix A: Answers to Review Questions
- Chapter 1 Fundamentals of the Clinical Laboratory
- Chapter 2 Safety: Patient and Clinical Laboratory Practices
- Chapter 3 Quality Assessment and Quality Control in the Clinical Laboratory
- Chapter 4 Phlebotomy: Collecting and Processing Patient Blood Specimens
- Chapter 5 The Microscope
- Chapter 6 Systems of Measurement, Laboratory Equipment, and Reagents
- Chapter 7 Laboratory Mathematics and Solution Preparation
- Chapter 8 Basic and Contemporary Techniques in the Clinical Laboratory
- Chapter 9 Laboratory Testing: From Point of Care to Total Automation
- Chapter 10 Introduction to the Principles and Practice of Clinical Chemistry
- Chapter 11 An Introduction to the Principles and Practice of Clinical Hematology
- Chapter 12 Hemostasis and Blood Coagulation
- Chapter 13 Renal Physiology and Urinalysis
- Chapter 14 Examination of Body Fluids and Miscellaneous Specimens
- Chapter 15 Introduction to Medical Microbiology
- Chapter 16 Immunology
- Chapter 17 Immunohematology and Transfusion Medicine
- Appendix B: Disease/Organ Panels
- AMA-designated laboratory testing panels
- Representative examples of laboratory testing related to a specific disorder or disease
- Glossary
- Index
- Language: English
- Edition: 8
- Published: December 22, 2018
- Imprint: Mosby
- eBook ISBN: 9780323549837
MT
Mary Louise Turgeon
Mary Louise Turgeon, EdD, MLS(ASCP)CM, is an educator, author, and consultant in medical laboratory science education. Her career includes roles as a community college professor, Medical Laboratory Technology program director, undergraduate and graduate university professor, Medical Laboratory Science program director, and departmental chairperson. Dr. Turgeon is currently an ad hoc educational content specialist for the College of Professional Studies, Northeastern University, Boston,
and maintains an active clinical laboratory science consulting practice. Her practice, Mary L. Turgeon and Associates, focuses on new program development, curriculum revision, and increasing teaching effectiveness
through the use of technology and interactive teaching strategies.
Affiliations and expertise
Associate Professor (Adjunct), University of Texas Medical Branch, Galveston, Texas; Clinical Laboratory Education Consultant, Mary L. Turgeon and Associates, Boston, Massachusetts; St. Petersburg, Florida