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Tietz Textbook of Clinical Chemistry and Molecular Diagnostics

  • 4th Edition - July 8, 2005
  • Latest edition
  • Authors: Carl A. Burtis, Edward R. Ashwood, David E. Bruns
  • Language: English

Bridging the gap between the clinical laboratory and medical management by relating pathophysiology to analytical results in health and disease, this classic resource provides the… Read more

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Description

Bridging the gap between the clinical laboratory and medical management by relating pathophysiology to analytical results in health and disease, this classic resource provides the guidance necessary to select, perform, and evaluate the results of new and established laboratory tests. Its up-to-date, encyclopedic coverage of the field defines analytical criteria for the medical usefulness of laboratory procedures, introduces new approaches for establishing reference ranges, describes variables that affect tests and results, examines modern analytical tools and their impact on lab management and costs, and demonstrates the applications of statistical methods.

Key features

  • All three editors are well known in the clinical chemistry world, and they bring a wealth of expertise to this reference.
  • Encompasses the tremendous strides made in clinical laboratory medicine in recent years — keeping readers completely up to date.
  • Nearly 800 tables and figures illustrate key issues in clinical chemistry.
  • A comprehensive chapter containing tables of reference values provides one location for comparing and evaluating test results.

Table of contents

Section 1 Laboratory Principles

1. Introduction to Principles of Laboratory Analyses and Safety

2. Specimen Collection and Processing

Section 2 Analytical Techniques and Instrumentation

3. Optical Techniques

4. Electrochemistry and Chemical Sensors

5. Electrophoresis

6. Chromatography

7. Mass Spectometry

8. Principles of Clinical Enzymology

9. Principles of Immunochemical Techniques

10. Nanotechnology and Microfabrication

11. Automation in the Clinical Laboratory

12. Point-of-Care Testing

Section 3 Principles of Laboratory Medicine

13. Introduction to Laboratory Medicine and Evidence-Based Laboratory Medicine

14. Selection and Analytical Evaluation of Methods—with Statistical Techniques

15. Clinical Evaluation of Methods

16. Establishment and Use of Reference Values

17. Preanalytical Variables and Biological Variation

18. Clinical Laboratory Informatics

19. Quality Management

Section 4 Analytes

20. Amino Acids, Peptides, and Proteins

21. Enzymes

22. Cytokines

23. Tumor Markers

24. Kidney Function Tests

25. Carbohydrates

26. Lipids, Lipoproteins, Apolipoproteins, and Other Cardiovascular Risk Factors

27. Electrolytes and Blood Gases

28. Hormones

29. Catecholamines and Serotonin

30. Vitamins and Trace Elements

31. Hemoglobin, Iron, and Bilirubin

32. Porphyrins and Disorders of Porphyrin Metabolism

33. Therapeutic Drugs and Their Management

34. Clinical Toxicology

35. Toxic Metals

Section 5 Molecular Diagnostics and Genetics

36. Principles of Molecular Biology and Approaches to Nucleic Acid Isolation

37. Nucleic Acid Techniques

38. Design and Operation of the Molecular Diagnostics Laboratory

39. Molecular Genetics and Diagnosis of Hematopoietic Neoplasms

40. Inherited Diseases

41. Identity Assessment

42. Molecular Methods in Diagnosis and Monitoring of Infectious Diseases

43. Pharmacogenetics

Section 6 Pathophysiology

44. Cardiac Function

45. Kidney Disease

46. Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism

47. Liver Disease

48. Gastric, Pancreatic, and Intestinal Function

49. Mineral and Bone Metabolism

50. Pituitary Function

51. The Adrenal Cortex

52. The Thyroid—Pathophysiology and Thyroid Function Testing

53. Reproductive Related Disorders

54. Clinical Chemistry of Pregnancy

55. Inborn Errors of Amino Acid, Organic Acid, and Fatty Acid Metabolism

Section 7 Appendix

56. Reference Information for the Clinical Laboratory

Product details

  • Edition: 4
  • Latest edition
  • Published: July 8, 2005
  • Language: English

About the authors

CB

Carl A. Burtis

Affiliations and expertise
Health Services Division, Oak Ridge National Laboratory, Oak Ridge, TN, and Clinical Professor of Pathology, University of Utah School of Medicine, Salt Lake City, UT

EA

Edward R. Ashwood

Affiliations and expertise
Professor of Pathology, University of Utah School of Medicine, and President and CEO, ARUP Laboratories, Salt Lake City, UT

DB

David E. Bruns

Affiliations and expertise
Professor of Pathology, University of Virginia School of Medicine, Director of Clinical Chemistry and Associate Director of Molecular Diagnostics, University of Virginia Health System, Charlottesville, VA, and Former Editor, Clinical Chemistry, Washington, DC