1. Membrane composition and properties
Lipid rafts (open)
Membrane tethers
(R Waugh, Rochester)
Microvilli
(JY Shao, Wash U)
Whole cell deformation
(D Khismatullin, Tulane)
2. Adhesion molecules
Integrin activation
(M. Shimaoka, Harvard)
Cytoskeletal anchoring
(Fred Pavalko, Iowa)
No tile yet
(Alon, Weizman)
Catch bonds
(Cheng Zhu, Georgia Tech and Roger McEver, OMRF)
Modeling adhesion
(Pospieszalska/Ley, LIAI)
Factors limiting the onset of bond formation at cell interfaces
(R Waugh, Rochester)
3. Active role of endothelial cells
Adhesive platforms
(O. Barreiro, Madrid)
Migratory cups, podosomes
(Chris Carman, Beth Israel)
PECAM recycling
(WA Muller, Northwestern)
4. Methods
1. FRET
(Minsoo Kim, Rochester)
2. Flow chambers
(Simon SI at UC Davis)