Lehne's Pharmacology for Nursing Care
- 11th Edition - September 10, 2021
- Authors: Jacqueline Rosenjack Burchum, Laura D. Rosenthal
- Language: English
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 2 5 2 6 - 9
Trust Lehne’s to make pharmacology more approachable! Known for its clear explanations of drug prototypes and how they work, Lehne's Pharmacology for Nursing Care, 11th Edition… Read more
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Request a sales quoteTrust Lehne’s to make pharmacology more approachable! Known for its clear explanations of drug prototypes and how they work, Lehne's Pharmacology for Nursing Care, 11th Edition provides a solid understanding of key drugs and their implications for nursing care. A perennial student favorite, this book simplifies complex pharmacology concepts, using large and small print to distinguish need-to-know drug content from the material that’s merely nice to know. It also includes in-depth coverage of physiology, pathophysiology and drug therapy. Written by noted nursing educators Jacqueline Rosenjack Burchum and Laura Rosenthal, this text helps you understand and apply pharmacology principles as opposed to simply memorizing drug facts.
- Clear, engaging writing style simplifies complex concepts, making difficult pharmacology content not only understandable but actually enjoyable.
- Prototype Drugs approach focuses on representative drugs that characterize all members of a given drug group, so that you can apply your understanding to related drugs currently on the market as well as drugs that will be released in the future.
- Nursing implications of drug therapy are integrated throughout the text to reinforce the integral relationship between drug therapy and nursing care, and also summarized in Summary of Major Nursing Implications sections at the end of chapters.
- Special Interest Topic boxes examine the everyday impact of pharmacology with vignettes including Medication Overuse Headache: Too Much of a Good Thing and Antibiotics in Animal Feed: Dying for a Hamburger and Chicken Nuggets.
- Large print highlights essential, need-to-know information, and small print indicates nice-to-know information.
- Safety Alerts call out important safety concerns related to contraindications, adverse effects, and more.
- Patient-Centered Care Across the Life Span tables highlight safe and appropriate care for patients throughout their lives, from infancy to older adulthood.
- Concise drug summary tables present key information for individual drugs, including drug class, generic and trade names, dosages, routes, and indications.
Undergraduate nursing students studying nursing pharmacology in BSN and higher-level ADN programs (ESF – 447,075 students
PSE – 98,373 students)
- Title of Book
- Cover image
- Title page
- Table of Contents
- Evolve Student Resources
- Copyright
- Dedication
- About the Authors
- Contributors and Reviewers
- Preface
- Laying Foundations in Basic Principles
- Reviewing Physiology and Pathophysiology
- Teaching Through Prototypes
- Large Print and Small Print: A Way to Focus on Essentials
- Using Clinical Reality to Prioritize Content
- Nursing Implications: Demonstrating the Application of Pharmacology in Nursing Practice
- What's New in the Book?
- Learning Supplements for Students
- Teaching Supplements for Instructors
- Ways to Use This Textbook
- Acknowledgments
- Unit I: Introduction
- Chapter 1. Orientation to Pharmacology
- Four Basic Terms
- Properties of an Ideal Drug
- The Therapeutic Objective
- Factors that Determine the Intensity of Drug Responses
- Chapter 2. Application of Pharmacology in Nursing Practice
- Evolution of Nursing Responsibilities Regarding Drugs
- Application of Pharmacology in Patient Care
- Application of Pharmacology in Patient Education
- Application of the Nursing Process in Drug Therapy
- Chapter 3. Drug Regulation, Development, Names, and Information
- Landmark Drug Legislation
- Hazardous Drug Exposure
- New Drug Development
- Drug Names
- Over-the-Counter Drugs
- Sources of Drug Information
- Unit II: Basic Principles of Pharmacology
- Chapter 4. Pharmacokinetics
- Application of Pharmacokinetics in Therapeutics
- A Note to Chemophobes
- Passage of Drugs Across Membranes
- Absorption
- Distribution
- Metabolism
- Excretion
- Time Course of Drug Responses
- Chapter 5. Pharmacodynamics
- Dose-Response Relationships
- Drug-Receptor Interactions
- Drug Responses that do not Involve Receptors
- Interpatient Variability in Drug Responses
- The Therapeutic Index
- Chapter 6. Drug Interactions
- Drug-Drug Interactions
- Drug-Food Interactions
- Drug-Supplement Interactions
- Chapter 7. Adverse Drug Reactions and Medication Errors
- Adverse Drug Reactions
- Medication Errors
- Chapter 8. Individual Variation in Drug Responses
- Body Weight and Composition
- Age
- Pathophysiology
- Tolerance
- Placebo Effect
- Variability in Absorption
- Genetics and Pharmacogenomics
- Gender- and Race-Related Variations
- Comorbidities and Drug Interactions
- Diet
- Failure to Take Medicine as Prescribed
- Chapter 9. Genetic and Genomic Considerations
- Pharmacogenomics
- Genomics Education and Competencies
- Application of Pharmacogenomics
- Genetic Variants that Alter Drug Metabolism
- Genetic Variants that Alter Drug Targets
- Genetic Variants that Alter Immune Responses to Drugs
- Genetic and Pharmacogenomic Testing
- Barriers to Pharmacogenomic Application in Practice
- Chapter 10. Introduction to Immunomodulators
- Monoclonal Antibodies “MAbs”
- Tyrosine Kinase Inhibitors “NIBS”
- Proteasome Inhibitors “MIBS”
- Immunotherapy of the Future
- Unit III: Drug Therapy Across The Life Span
- Chapter 11. Drug Therapy During Pregnancy and Breast-Feeding
- Drug Therapy During Pregnancy: Basic Considerations
- Drug Therapy During Pregnancy: Teratogenesis and Other Risks
- Drug Therapy During Breast-Feeding
- Chapter 12. Drug Therapy in Pediatric Patients
- Pharmacokinetics: Neonates And Infants
- Pharmacokinetics: Children 1 Year and Older
- Adverse Drug Reactions
- Dosage Determination
- Promoting Adherence
- Chapter 13. Drug Therapy in Older Adults
- Pharmacokinetic Changes in Older Adults
- Pharmacodynamic Changes in Older Adults
- Adverse Drug Reactions and Drug Interactions
- Promoting Adherence
- Considerations for End-of-Life Care
- Unit IV: Peripheral Nervous System Drugs
- Section 1: Introduction
- Chapter 14. Basic Principles of Neuropharmacology
- How Neurons Regulate Physiologic Processes
- Basic Mechanisms By Which Neuropharmacologic Agents Act
- Multiple Receptor Types and Selectivity of Drug Action
- An Approach to Learning About Peripheral Nervous System Drugs
- Chapter 15. Physiology of the Peripheral Nervous System
- Divisions of the Nervous System
- Overview of Autonomic Nervous System Functions
- Autonomic Nervous System Regulation of Physiologic Processes
- Anatomic Considerations
- Transmitters of the Peripheral Nervous System
- Receptors of the Peripheral Nervous System
- Exploring the Concept of Receptor Subtypes
- Locations of Receptor Subtypes
- Functions of Cholinergic and Adrenergic Receptor Subtypes
- Transmitter Life Cycles
- Section 2: Cholinergic Drugs
- Chapter 16. Muscarinic Agonists
- Introduction to Cholinergic Drugs
- Muscarinic Agonists
- Chapter 17. Muscarinic Antagonists
- Muscarinic Antagonists (Anticholinergic Drugs)
- Other Muscarinic Antagonists
- Drugs for Overactive Bladder
- Toxicology of Muscarinic Antagonists
- Chapter 18. Cholinesterase Inhibitors and Their Use in Myasthenia Gravis
- Reversible Cholinesterase Inhibitors
- Irreversible Cholinesterase Inhibitors
- Myasthenia Gravis
- Chapter 19. Drugs That Block Nicotinic Cholinergic Transmission
- Control of Muscle Contraction
- Competitive (Nondepolarizing) Neuromuscular Blockers
- Depolarizing Neuromuscular Blockers
- Therapeutic Uses of Neuromuscular Blockers
- Section 3: Adrenergic Drugs
- Chapter 20. Adrenergic Agonists
- Mechanisms of Adrenergic Receptor Activation
- Overview of the Adrenergic Agonists
- Therapeutic Applications and Adverse Effects of Adrenergic Receptor Activation
- Properties of Representative Adrenergic Agonists
- Chapter 21. Adrenergic Antagonists
- Alpha-Adrenergic Antagonists
- Beta-Adrenergic Antagonists
- Chapter 22. Indirect-Acting Antiadrenergic Agents
- Centrally Acting Alpha2 Agonists
- Unit V: Central Nervous System Drugs
- Section 4: Introduction
- Chapter 23. Introduction to Central Nervous System Pharmacology
- Transmitters of the CNS
- The Blood-Brain Barrier
- How Do CNS Drugs Produce Therapeutic Effects?
- Adaptation of the CNS to Prolonged Drug Exposure
- Development of New Psychotherapeutic Drugs
- Approaching the Study of CNS Drugs
- Section 5: Drugs for Neurodegenerative Disorders
- Chapter 24. Drugs for Parkinson Disease
- Pathophysiology That Underlies Motor Symptoms
- Overview of Motor Symptom Management
- Pharmacology of Drugs Used for Motor Symptoms
- Nonmotor Symptoms and Their Management
- Chapter 25. Drugs for Alzheimer Disease
- Pathophysiology
- Risk Factors and Symptoms
- Drugs for Cognitive Impairment
- Drugs for Neuropsychiatric Symptoms
- Can We Prevent Alzheimer Disease Or Delay Cognitive Decline?
- Chapter 26. Drugs for Multiple Sclerosis
- Overview of MS and ITS Treatment
- Disease-Modifying Drugs I: Immunomodulators
- Disease-Modifying Drugs II: Immunosuppressants
- Drugs Used to Manage MS Symptoms
- Section 6: Neurologic Drugs
- Chapter 27. Drugs for Seizure Disorders
- Generation of Seizures
- Types of Seizures
- How Antiseizure Drugs Work
- Basic Therapeutic Considerations
- Classification of Antiseizure Drugs
- Traditional Antiseizure Drugs
- New Generation Antiseizure Drugs
- Management of Generalized Convulsive Status Epilepticus
- Chapter 28. Drugs for Muscle Spasm and Spasticity
- Drugs for Spasticity
- Drugs for Localized Muscle Spasm
- Other Centrally Acting Muscle Relaxants
- Section 7: Drugs for Pain
- Chapter 29. Local Anesthetics
- Basic Pharmacology of Local Anesthetics
- Properties of Individual Local Anesthetics
- Clinical use of Local Anesthetics
- Chapter 30. General Anesthetics
- Inhalation Anesthetics
- Intravenous Anesthetics
- Chapter 31. Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics
- Opioid Analgesics
- Opioid Antagonists
- Chapter 32. Pain Management in Patients With Cancer
- Pathophysiology of Pain
- Management Strategy
- Assessment and Ongoing Evaluation
- Drug Therapy
- Nondrug Therapy
- Pain Management in Special Populations
- Patient Education
- Chapter 33. Drugs for Headache
- Migraine Headache
- Overview of Treatment
- Cluster Headaches
- Section 8: Psychotherapeutic Drugs
- Chapter 34. Antipsychotic Agents and Their Use in Schizophrenia
- Schizophrenia: Clinical Presentation and Etiology
- First-Generation (Conventional) Antipsychotics
- Second-Generation (Atypical) Antipsychotics
- Depot Antipsychotic Preparations
- Management of Schizophrenia
- Chapter 35. Antidepressants
- Major Depression: Clinical Features, Pathogenesis, and Treatment Overview
- Drugs Used for Depression
- Peripartum Depression
- Chapter 36. Drugs for Bipolar Disorder
- Characteristics of Bipolar Disorder
- Treatment of Bipolar Disorder
- Mood-Stabilizing Drugs
- Antipsychotic Drugs
- Chapter 37. Sedative-Hypnotic Drugs
- Benzodiazepines
- Benzodiazepine-Like Drugs
- Ramelteon: A Melatonin Agonist
- Suvorexant: An Orexin Antagonist
- Barbiturates
- Management of Insomnia
- Chapter 38. Management of Anxiety Disorders
- Generalized Anxiety Disorder
- Panic Disorder
- Obsessive-Compulsive Disorder
- Social Anxiety Disorder
- Post-Traumatic Stress Disorder
- Chapter 39. Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder
- Central Nervous System Stimulants
- Attention-Deficit/Hyperactivity Disorder
- Section 9: Substance Use Disorders
- Chapter 40. Substance Use Disorders I: Basic Considerations
- Definitions
- Diagnostic Criteria Regarding Substance Use Disorder
- Factors That Contribute To Substance Use Disorder
- Neurobiology of Substance Use Disorders
- Principles of Substance Use Disorder Treatment
- The Controlled Substances Act
- Chapter 41. Substance Use Disorders II: Alcohol
- Basic Pharmacology of Alcohol
- Alcohol Use Disorder
- Drugs for Alcohol Use Disorder
- Chapter 42. Substance Use Disorders III: Nicotine
- Basic Pharmacology of Nicotine
- Pharmacologic AIDS to Smoking Cessation
- Chapter 43. Substance Use Disorders IV: Major Drugs of Abuse Other Than Alcohol and Nicotine
- Heroin, Oxycodone, and Other Opioids
- Kratom
- General Central Nervous System Depressants
- Psychostimulants
- Marijuana and Related Preparations
- Psychedelics
- Dissociative Drugs
- Dextromethorphan
- 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)
- Inhalants
- Anabolic Steroids
- Unit VI: Drugs That Affect Fluid and Electrolyte Balance
- Chapter 44. Diuretics
- Review of Renal Anatomy and Physiology
- Introduction to Diuretics
- Loop Diuretics
- Thiazides and Related Diuretics
- Potassium-Sparing Diuretics
- Mannitol: An Osmotic Diuretic
- Chapter 45. Agents Affecting the Volume and Ion Content of Body Fluids
- Disorders of Fluid Volume and Osmolality
- Acid-Base Disturbances
- Potassium Imbalances
- Magnesium Imbalances
- Unit VII: Drugs That Affect The Heart, Blood Vessels, and Blood
- Chapter 46. Review of Hemodynamics
- Overview of the Circulatory System
- Regulation of Cardiac Output
- Regulation of Arterial Pressure
- Chapter 47. Drugs Acting on the Renin-Angiotensin-Aldosterone System
- Physiology of the Renin-Angiotensin-Aldosterone System
- Angiotensin-Converting Enzyme Inhibitors
- Angiotensin II Receptor Blockers
- Aliskiren: A Direct Renin Inhibitor
- Aldosterone Antagonists
- Chapter 48. Calcium Channel Blockers
- Calcium Channels: Physiologic Functions and Consequences of Blockade
- Calcium Channel Blockers: Classification and Sites of Action
- NonDihydropyridines: Verapamil and Diltiazem: Agents That Act on Vascular Smooth Muscle and the Heart
- Dihydropyridines: Agents That Act Mainly on Vascular Smooth Muscle
- Chapter 49. Vasodilators
- Basic Concepts in Vasodilator Pharmacology
- Pharmacology of Individual Vasodilators
- Chapter 50. Drugs for Hypertension
- Basic Considerations in Hypertension
- Management of Chronic Hypertension
- Drugs For Hypertensive Emergencies
- Drugs For Hypertensive Disorders of Pregnancy
- Chapter 51. Drugs for Heart Failure
- Pathophysiology of Heart Failure
- Overview of Drugs Used to Treat Heart Failure
- Digoxin: A Cardiac Glycoside
- Management of Heart Failure
- Chapter 52. Antidysrhythmic Drugs
- Cardiac Electrophysiology, Dysrhythmias, and the Antidysrhythmic Drugs
- Pharmacology of the Antidysrhythmic Drugs
- Chapter 53. Drugs That Help Normalize Cholesterol and Triglyceride Levels
- Cholesterol
- Plasma Lipoproteins
- Role of LDL Cholesterol in Atherosclerosis
- 2018 ACC/AHA Guidelines on the Management of Blood Cholesterol
- Drugs and other Products used to Improve Plasma Lipid Levels
- Chapter 54. Drugs for Angina Pectoris
- Determinants of Cardiac Oxygen Demand and Oxygen Supply
- Angina Pectoris: Pathophysiology and Treatment Strategy
- Organic Nitrates
- Beta Blockers
- Calcium Channel Blockers
- Ranolazine
- Treatment Measures
- Chapter 55. Anticoagulant, Antiplatelet, and Thrombolytic Drugs
- Coagulation: Physiology and Pathophysiology
- Overview of Drugs for Thromboembolic Disorders
- Chapter 56. Management of ST-Elevation Myocardial Infarction
- Pathophysiology of STEMI
- Diagnosis of STEMI
- Management of STEMI
- Complications of STEMI
- Secondary Prevention of STEMI
- Chapter 57. Drugs for Hemophilia
- Basic Considerations
- Preparations Used to Treat Hemophilia
- Chapter 58. Drugs for Deficiency Anemias
- Red Blood Cell Development
- Iron Deficiency
- Biochemistry And Physiology of Iron
- Iron Deficiency: Causes, Consequences, And Diagnosis
- Oral Iron Preparations
- Parenteral Iron Preparations
- Guidelines For Treating Iron Deficiency
- Vitamin B12 Deficiency
- Biochemistry and Physiology of Vitamin B12
- Vitamin B12 Deficiency: Causes, Consequences, And Diagnosis
- Vitamin B12 Preparations: Cyanocobalamin
- Guidelines for Treating Vitamin B12 Deficiency
- Folic Acid Deficiency
- Physiology And Biochemistry of Folic Acid
- Folic Acid Deficiency: Causes, Consequences, And Diagnosis
- Folic Acid Preparations
- Guidelines For Treating Folic Acid Deficiency
- Chapter 59. Hematopoietic Agents
- Hematopoietic Growth Factors
- Erythropoietic Growth Factors
- Leukopoietic Growth Factors
- Drugs That Mimic Hematopoietic Growth Factors Or Enhance Their Actions
- Thrombopoietin Receptor Agonists
- Unit VIII: Drugs for Endocrine Disorders
- Chapter 60. Drugs for Diabetes Mellitus
- Diabetes Mellitus
- Insulin
- Physiology
- Preparations and Administration
- Therapeutic Use
- Noninsulin Medications for the Treatment Of Diabetes
- Oral Drugs
- Adjunctive Agents
- Noninsulin Injectable Agents
- Acute Complications of Poor Glycemic Control
- Diabetic Ketoacidosis
- Hyperosmolar Hyperglycemic State
- Glucagon for Treatment of Severe Hypoglycemia
- Chapter 61. Drugs for Thyroid Disorders
- Thyroid Physiology
- Thyroid Function Tests
- Thyroid Pathophysiology
- Thyroid Hormone Preparations for Hypothyroidism
- Drugs for Hyperthyroidism
- Chapter 62. Drugs Related to Hypothalamic and Pituitary Function
- Overview of Hypothalamic and Pituitary Endocrinology
- Growth Hormone
- Prolactin
- Antidiuretic Hormone (Vasopressin)
- Drugs for Acromegaly
- Chapter 63. Drugs for Disorders of the Adrenal Cortex
- Physiology of the Adrenocortical Hormones
- Pathophysiology of the Adrenocortical Hormones
- Agents for Replacement Therapy in Adrenocortical Insufficiency
- Agents for Diagnosing Adrenocortical Disorders
- Unit IX: Women’s Health
- Chapter 64. Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications
- The Menstrual Cycle
- Estrogens
- Selective Estrogen Receptor Modulators
- Phytoestrogens
- Progestins
- Menopausal Hormone Therapy
- Chapter 65. Birth Control
- Effectiveness of Birth Control Methods
- Selecting a Birth Control Method
- Oral Contraceptives
- Combination Contraceptives with Novel Delivery Systems
- Long-Acting Contraceptives
- Spermicides
- Drugs for Medical Abortion
- Chapter 66. Drug Therapy for Infertility
- Infertility: Causes and Treatment Strategies
- Drugs Used to Treat Female Infertility
- Chapter 67. Drugs That Affect Uterine Function
- Drugs for Preterm Labor
- Drugs for Cervical Ripening and Induction of Labor
- Drugs for Postpartum Hemorrhage
- Drugs for Menorrhagia
- Unit X: Men’s Health
- Chapter 68. Androgens
- Testosterone
- Clinical Pharmacology of the Androgens
- Androgen Preparations for Male Hypogonadism
- Androgen (Anabolic Steroid) Abuse
- Chapter 69. Drugs for Male Sexual Dysfunction and Benign Prostatic Hyperplasia
- Male Sexual Dysfunction
- Erectile Dysfunction
- Physiology Of Erection
- Oral Drugs For Erectile Dysfunction: PDE5 Inhibitors
- Nonoral Drugs For Erectile Dysfunction
- Premature Ejaculation
- Pathophysiology
- Drug Therapy For Premature Ejaculation
- Benign Prostatic Hyperplasia
- Pathophysiology
- Treatment Modalities
- Unit XI: Antiinflammatory, Antiallergic, and Immunologic Drugs
- Chapter 70. Review of the Immune System
- Introduction to the Immune System
- Antibody-Mediated (Humoral) Immunity
- Cell-Mediated Immunity
- Chapter 71. Childhood Immunization
- General Considerations
- Target Diseases
- Specific Vaccines and Toxoids
- Experimental Vaccines
- Chapter 72. Immunosuppressants
- Calcineurin Inhibitors
- mTOR Inhibitors
- Glucocorticoids
- Cytotoxic Drugs
- Antibodies
- Chapter 73. Antihistamines
- Histamine
- The Two Types of Antihistamines: H1 Antagonists and H2 Antagonists
- Histamine1 Antagonists I: Basic Pharmacology
- Histamine1 Antagonists II: Preparations
- Chapter 74. Cyclooxygenase Inhibitors: Nonsteroidal Antiinflammatory Drugs and Acetaminophen
- Mechanism of Action
- Classification of Cyclooxygenase Inhibitors
- First-Generation NSAIDs
- Second-Generation NSAIDs (COX-2 Inhibitors, Coxibs)
- Acetaminophen
- AHA Statement on the use of COX Inhibitors for Chronic Pain
- Chapter 75. Glucocorticoids in Nonendocrine Disorders
- Review of Glucocorticoid Physiology
- Pharmacology of Glucocorticoids
- Unit XII: Drugs for Bone and Joint Disorders
- Chapter 76. Drug Therapy for Rheumatoid Arthritis
- Pathophysiology of Rheumatoid Arthritis
- Overview of Therapy
- Nonsteroidal Antiinflammatory Drugs
- Glucocorticoids
- Conventional (Traditional) Disease-Modifying Antirheumatic Drugs
- Biologic Disease-Modifying Antirheumatic Drugs
- Interleukin-6 Receptor Antagonists
- Chapter 77. Drug Therapy for Gout
- Pathophysiology of Gout
- Overview of Drug Therapy
- Drugs for Acute Gout Flares
- Drugs For Hyperuricemia (Urate-Lowering Therapy)
- Chapter 78. Drugs Affecting Calcium Levels and Bone Mineralization
- Calcium Physiology
- Calcium-Related Pathophysiology
- Drugs for Disorders Involving Calcium and Bone Mineralization
- Osteoporosis
- Unit XIII: Respiratory Tract Drugs
- Chapter 79. Drugs for Asthma and Chronic Obstructive Pulmonary Disease
- Basic Considerations
- Antiinflammatory Drugs
- Bronchodilators
- Combination Drugs
- Management of Asthma and Chronic Obstructive Pulmonary Disease
- Management of Chronic Obstructive Pulmonary Disease
- Chapter 80. Drugs for Allergic Rhinitis, Cough, and Colds
- Drugs for Allergic Rhinitis
- Drugs for Cough
- Cold Remedies: Combination Preparations
- Unit XIV: Gastrointestinal Drugs
- Chapter 81. Drugs for Peptic Ulcer Disease
- Pathogenesis of Peptic Ulcers
- Overview of Treatment
- Antibacterial Drugs
- Histamine2 Receptor Antagonists
- Proton Pump Inhibitors
- Other Antiulcer Drugs
- Chapter 82. Laxatives
- General Considerations
- Basic Pharmacology of Laxatives
- Laxative Abuse
- Chapter 83. Other Gastrointestinal Drugs
- Antiemetics
- Drugs for Motion Sickness
- Antidiarrheal Agents
- Drugs for Irritable Bowel Syndrome
- Drugs for Inflammatory Bowel Disease
- Prokinetic Agents
- Palifermin
- Pancreatic Enzymes
- Drugs used to Dissolve Gallstones
- Anorectal Preparations
- Unit XV: Nutrition and Complementary Therapy
- Chapter 84. Vitamins
- What are Vitamins?
- Basic Considerations
- Fat-Soluble Vitamins
- Water-Soluble Vitamins
- Chapter 85. Drugs for Weight Loss
- Assessment of Weight-Related Health Risk
- Pathophysiology
- Overview of Obesity Treatment
- Weight-Loss Drugs
- A Note Regarding Drugs for Weight Loss
- Chapter 86. Complementary and Alternative Therapy
- Regulation of Dietary Supplements
- Private Quality Certification Programs
- Standardization of Herbal Products
- Adverse Interactions with Conventional Drugs
- Some Commonly Used Dietary Supplements
- Harmful Supplements to Avoid
- Unit XVI: Drugs for Infectious Diseases
- Chapter 87. Basic Principles of Antimicrobial Therapy
- Selective Toxicity
- Classification of Antimicrobial Drugs
- Acquired Resistance to Antimicrobial Drugs
- Selection of Antibiotics
- Host Factors that Modify Drug Choice, Route of Administration, or Dosage
- Dosage and Duration of Treatment
- Therapy with Antibiotic Combinations
- Prophylactic use of Antimicrobial Drugs
- Misuses of Antimicrobial Drugs
- Monitoring Antimicrobial Therapy
- Chapter 88. Drugs That Weaken the Bacterial Cell Wall I: Penicillins
- Introduction to the Penicillins
- Properties of Individual Penicillins
- Chapter 89. Drugs That Weaken the Bacterial Cell Wall II: Other Drugs
- Cephalosporins
- Carbapenems
- Other Inhibitors of Cell Wall Synthesis
- Lipoglycoproteins
- Chapter 90. Bacteriostatic Inhibitors of Protein Synthesis: Tetracyclines, Macrolides, and Others
- Tetracyclines
- Macrolides
- Other Bacteriostatic Inhibitors of Protein Synthesis
- Chapter 91. Aminoglycosides: Bactericidal Inhibitors of Protein Synthesis
- Basic Pharmacology of the Aminoglycosides
- Properties of Individual Aminoglycosides
- Chapter 92. Sulfonamide Antibiotics and Trimethoprim
- Sulfonamides
- Trimethoprim
- Trimethoprim/Sulfamethoxazole
- Chapter 93. Drug Therapy for Urinary Tract Infections
- Organisms that Cause Urinary Tract Infections
- Specific Urinary Tract Infections and Their Treatment
- Urinary Tract Antiseptics
- Chapter 94. Antimycobacterial Agents
- Drugs for Tuberculosis
- Drugs for Leprosy (Hansen Disease)
- Drugs for Mycobacterium Avium Complex Infection
- Chapter 95. Miscellaneous Antibacterial Drugs
- Fluoroquinolones
- Additional Antibacterial Drugs
- Chapter 96. Antifungal Agents
- Drugs for Systemic Mycoses
- Drugs for Superficial Mycoses
- Chapter 97. Antiviral Agents I: Drugs for Non-HIV Viral Infections
- Drugs for Infection with Herpes Simplex Viruses and Varicella-Zoster Virus
- Drugs for Cytomegalovirus Infection
- Viral Hepatitis
- Drugs for Influenza
- Drugs for Respiratory Syncytial Virus Prophylaxis
- Chapter 98. Antiviral Agents II: Drugs for HIV Infection and Related Opportunistic Infections
- Pathophysiology
- Classification of Antiretroviral Drugs
- Drug Interactions
- Nucleoside/Nucleotide Reverse Transcriptase Inhibitors
- Nonnucleoside Reverse Transcriptase Inhibitors
- Protease Inhibitors
- Integrase Strand Transfer Inhibitors
- HIV Fusion Inhibitors
- CCR5 Antagonists
- Post-Attachment Inhibitors
- Management of HIV Infection
- Preventing HIV Infection with Drugs
- Prophylaxis and Treatment of Opportunistic Infections
- Herpes Simplex Virus Infection
- HIV Vaccines
- Keeping Current
- Chapter 99. Drug Therapy for Sexually Transmitted Infections
- Chlamydia Trachomatis Infections
- Gonococcal Infections
- Nongonococcal Urethritis
- Pelvic Inflammatory Disease
- Acute Epididymitis
- Syphilis
- Acquired Immunodeficiency Syndrome
- Bacterial Vaginosis
- Trichomoniasis
- Chancroid
- Herpes Simplex Virus Infections
- Proctitis
- Anogenital Warts
- Making Sense of Treatment
- Chapter 100. Antiseptics and Disinfectants
- General Considerations
- Properties of Individual Antiseptics and Disinfectants
- Hand Hygiene for Healthcare Workers
- Unit XVII: Drugs for Parasitic Diseases
- Chapter 101. Anthelmintics
- Classification of Parasitic Worms
- Helminthic Infestations
- Drugs of Choice for Helminthiasis
- Chapter 102. Antiprotozoal Drugs I: Antimalarial Agents
- Life Cycle of the Malaria Parasite
- Types of Malaria
- Principles of Antimalarial Therapy
- Pharmacology of the Major Antimalarial Drugs
- Chapter 103. Antiprotozoal Drugs II: Miscellaneous Agents
- Protozoal Infections
- Drugs of Choice for Protozoal Infections
- Chapter 104. Ectoparasiticides
- Ectoparasitic Infestations
- Pharmacology of Ectoparasiticides
- Unit XVIII: Cancer Therapy
- Chapter 105. Basic Principles of Cancer Therapy
- What is Cancer?
- The Growth Fraction and its Relationship to Chemotherapy
- Obstacles to Successful Chemotherapy
- Strategies for Achieving Maximum Benefits from Chemotherapy
- Major Toxicities of Chemotherapeutic Drugs
- Making the Decision to Treat
- Looking Ahead
- Chapter 106. Anticancer Drugs I: Cytotoxic Agents
- Introduction to the Cytotoxic Anticancer Drugs
- Alkylating Agents
- Platinum Compounds
- Antimetabolites
- Hypomethylating Agents
- Antitumor Antibiotics
- Mitotic Inhibitors
- Topoisomerase Inhibitors
- Miscellaneous Cytotoxic Drugs
- Chapter 107. Anticancer Drugs II: Noncytotoxic Agents
- Drugs for Breast Cancer
- Drugs for Prostate Cancer
- Targeted Anticancer Drugs
- Immunostimulants
- Unit XIX: Drugs For Eyes, Ears, And Skin
- Chapter 108. Drugs for Eye Conditions and Diseases
- Drugs for Glaucoma
- Cycloplegics and Mydriatics
- Drugs for Allergic Conjunctivitis
- Drugs for Age-Related Macular Degeneration
- Additional Ophthalmic Drugs
- Chapter 109. Drugs for Skin Conditions
- Anatomy of the Skin
- Topical Drug Formulations
- Topical Glucocorticoids
- Keratolytic Agents
- Acne
- Drugs for Rosacea
- Sunscreens
- Psoriasis
- Drugs for Actinic Keratoses
- Drugs for Atopic Dermatitis
- Agents for Wart Removal
- Drugs for Miscellaneous Skin and Hair Conditions
- Skin Infections and Infestations
- Local Anesthetics
- Chapter 110. Drugs for Ear Conditions
- Anatomy of the Ear
- Otitis Media and its Management
- Acute Otitis Externa
- Unit XX: Toxicology
- Chapter 111. Management of Poisoning
- Fundamentals of Treatment
- Drugs and Procedures used to Minimize Poison Absorption
- Drugs and Procedures used for Poison Removal
- Specific Antidotes
- Poison Control Centers
- Chapter 112. Potential Weapons of Biologic, Radiologic, and Chemical Terrorism
- Bacteria and Viruses
- Biotoxins
- Chemical Weapons
- Radiologic Weapons
- Appendix A. Canadian Drug Information*
- Canadian Drug Legislation
- Prescription Drugs (Schedule F)
- Cannabis in Canada
- Nonprescription Medications—National Drug Schedules
- New Drug Development in Canada
- Patent Laws
- Drug Advertising
- International System of Units
- Drug Serum Concentrations
- Further Reading
- Appendix B. Prototype Drugs and Their Major Uses
- Peripheral Nervous System Drugs
- Central Nervous System Drugs
- Diuretics
- Drugs That Affect the Heart, Blood Vessels, and Blood
- Drugs for Endocrine Disorders
- Women’s Health
- Men’s Health
- Antiinflammatory, Antiallergic, and Immunologic Drugs
- Drugs for Bone and Joint Disorders
- Respiratory Tract Drugs
- Gastrointestinal Drugs
- Drugs for Weight Loss
- Drugs for Bacterial Infections
- Drugs for Fungal Infections
- Drugs for Viral Infections
- Drugs for Parasitic Diseases
- Anticancer Drugs: Cytotoxic Agents
- Anticancer Drugs: Hormonal Agents, Targeted Drugs, and Other Noncytotoxic Anticancer Drugs
- Other Important Drugs
- Drugs for Hereditary Angioedema
- Index
- Special Interest Topics
- Language: English
- Edition: 11
- Published: September 10, 2021
- Imprint: Saunders
- eBook ISBN: 9780323825269
JB
Jacqueline Rosenjack Burchum
LR
Laura D. Rosenthal
Assistant Dean for DNP Programs, College of Nursing, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA