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Elsevier

Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases

  • 1st Edition - December 16, 2013
  • Latest edition
  • Author: Christophe Wiart
  • Language: English

Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases is the second volume in the series, Pharmaceutical Leads from Medicinal Plants. This… Read more

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Description

Lead Compounds from Medicinal Plants for the Treatment of Neurodegenerative Diseases is the second volume in the series, Pharmaceutical Leads from Medicinal Plants. This book includes key pharmacological and chemical evidence to support the selection of promising pre-clinical candidates for the treatment of neurodegenerative diseases.

This important addition to the natural product and drug discovery literature contains the history, synonyms, medicinal uses, phytopharmacology, pre-clinical potential, and rationale for each plant selected. By providing critical evaluation of pharmacological data, mechanisms of action, and structural requirements for the development of future neuroprotective agents, this comprehensive reference is a beneficial resource for industry and academic scientists whose research focuses on neurodegenerative drug discovery and development.

Key features

  • Incorporates compelling biological activity data and preclinical structure-activity relationships to help you choose promising lead molecules for further research
  • Includes primary source references to the most recent natural product discoveries in the field of neuroprotection in order to promote new drug discovery in this area
  • Contains detailed discussions of important neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease
  • Each plant section includes a critical evaluation of pharmacological, chemical, and toxicological evidence to support the use of the compound in drug discovery research in neurodegeneration

Readership

Pharmaceutical scientists and neuroscientists involved in Central Nervous System drug discovery in both industry and academic settings

Table of contents

Foreword 1 by Atta-ur-Rahman

Foreword 2 by Derek J. McPhee

Foreword 3 by Cornelis J. Van der Schyf

Preface

About the Author

Chapter 1. Alkaloids

Introduction

Topic 1.1 Amide, Piperine, and Pyridine Alkaloids

Topic 1.2 Indole Alkaloids

Topic 1.3 Isoquinoline Alkaloids

Topic 1.4 Terpene Alkaloids

Chapter 2. Terpenes

Introduction

Topic 2.1 Monoterpenes

Topic 2.2 Sesquiterpenes

Topic 2.3 Diterpenes

Topic 2.4 Triterpenes

Chapter 3. Phenolics

Introduction

Topic 3.1 Benzopyrones

Topic 3.2 Quinones

Topic 3.3 Lignans

Index of Natural Products

Index of Pharmacological Terms

Index of Plants

Subject Index

Review quotes

"Wiart presents evidence that natural products are not only able to protect neurons and boost their activities, but also to induce neuritogenesis, raising the possibility that flowering plants helped apes evolve into Homo sapiens during the Tertiary period. In the near future, he says, they may also allow complete victory over neurodegenerative diseases…"—ProtoView.com, April 2014

Product details

  • Edition: 1
  • Latest edition
  • Published: January 22, 2014
  • Language: English

About the author

CW

Christophe Wiart

Dr. Christophe Wiart is a French pharmacist who for the last 25 years has traveled in various parts of Asia to study in situ the botany, the ancient traditional knowledge, and ethnopharmacology of medicinal plants to bring global awareness both in public and academia on the tremendous pharmaceutical value of medicinal plants of Asia and the Pacific. He has authored more than 14 academic books on this subject as well as peer-reviewed research papers. He was recently interviewed by BBC Radio Crowd Science (2020). He appeared on HBO's Vice (TV Series) in season 3, episode 6 (episode 28 of the series), titled "The Post-Antibiotic World & Indonesia's Palm Bomb." aired on April 17, 2015. Dr. Wiart was a guest in Aljazeera Inside Story " For only the fourth time in its 70-year history, the United Nations is holding a special meeting devoted to a health crisis." Dr. Christophe Wiart is a French pharmacist who for the last 25 years has traveled in various parts of Asia to study in situ the botany, the ancient traditional knowledge, and ethnopharmacology of medicinal plants to bring global awareness both in public and academia on the tremendous pharmaceutical value of medicinal plants of Asia and the Pacific. He has authored more than 14 academic books on this subject as well as peer-reviewed research papers. He was recently interviewed by BBC Radio Crowd Science (2020). He appeared on HBO's Vice (TV Series) in season 3, episode 6 (episode 28 of the series), titled "The Post-Antibiotic World & Indonesia's Palm Bomb." aired on April 17, 2015. Dr. Wiart was a guest in Aljazeera Inside Story " For only the fourth time in its 70-year history, the United Nations is holding a special meeting devoted to a health crisis."
Affiliations and expertise
Ethnopharmacologist and Associate Professor, School of Pharmacy, University of Nottingham, Malaysia Campus

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