
Kumar & Clark's Cases in Clinical Medicine
- 5th Edition - March 18, 2025
- Imprint: Elsevier
- Authors: Philip Xiu, Nicholas Aveyard
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 6 1 8 9 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 6 1 9 0 - 9
This award-winning book provides a comprehensive collection of over 200 real-life clinical cases designed to support clinical reasoning and enhance diagnostic and management skills… Read more

Purchase options

Institutional subscription on ScienceDirect
Request a sales quoteThis award-winning book provides a comprehensive collection of over 200 real-life clinical cases designed to support clinical reasoning and enhance diagnostic and management skills through case-based learning.
The cases cover a wide range of acute symptoms and conditions encountered in medicine, with clear and concise advice on diagnosis and management. The level of detail is ideal for exam revision as well as to support junior doctors and other healthcare professionals on the wards.
Now in its fifth edition, this latest Kumar & Clark has been fully updated by new editors who bring a wealth of clinical experience as well as a recent junior doctor perspective to this highly useful book.
The cases cover a wide range of acute symptoms and conditions encountered in medicine, with clear and concise advice on diagnosis and management. The level of detail is ideal for exam revision as well as to support junior doctors and other healthcare professionals on the wards.
Now in its fifth edition, this latest Kumar & Clark has been fully updated by new editors who bring a wealth of clinical experience as well as a recent junior doctor perspective to this highly useful book.
- More than 200 clinical cases covering various acute symptoms and conditions
- Includes the most common MLA conditions
- Concise, relevant, and fully updated with evidence-based information and the latest guidelines
- Clear advice on immediate and further management, complications, differential diagnoses, history-taking, tips, pitfalls, alerts, investigations, and prioritisation
- Key points reinforced through ‘Remember’, ‘Investigations’ and ‘Information’ boxes
- High-quality diagrams, tables, and photographs throughout
- An enhanced eBook version is included with purchase. The eBook allows you to access all the text, figures and references, with the ability to search, customise your content, make notes and highlights, and have content read aloud
Medical Students/ Trainees
- Cover Image
- Title Page
- Copyright
- Contents
- Acknowledgements
- Preface
- CHAPTER 1 Emergency Medicine and Toxicology
- Shock
- Anaphylaxis
- Acute Respiratory Distress Syndrome (ARDS)
- Self-Poisoning
- Paracetamol (Acetaminophen) Poisoning
- Salicylate Overdose
- Tricyclic Antidepressant Overdose
- Cocaine
- Ecstasy (See Fig. 1.6)
- Gamma Hydroxybutyric Acid (GHB)
- Significant Websites
- Further Reading
- CHAPTER 2 Cardiology
- Syncope
- A Clinical Approach to Patients With Tachycardia
- Atrial Fibrillation
- Bradycardia and Pacing
- Cardiac Arrest and Basic Life Support
- Chest Pain and Acute Coronary Syndromes
- Cardiogenic Shock
- Right Ventricular Infarction
- Heart Failure Following Myocardial Infarction
- Post-Infarction Arrhythmias and Heart Block
- Myocardial Infarction – Secondary Prevention
- Heart Failure Recognition and Acute Management
- Pericardial Disease
- Valvular Heart Disease
- Infective Endocarditis
- Pulmonary Hypertension
- Cardiomyopathies
- Hypertension (HTN)
- The Swollen/Painful Leg
- Further Reading
- CHAPTER 3 Respiratory Disorders
- Acute Breathlessness
- Cough
- Breathlessness and Wheeze
- Hyperventilation
- Haemoptysis
- Approach to Chest Pain
- Bronchiolitis
- Respiratory Failure
- COPD – Acute Exacerbation
- Pneumonia
- Lung Abscess
- Tuberculosis (TB)
- Pleural Effusion
- Pulmonary Embolism (and Deep Vein Thrombosis)
- Pneumothorax
- Carcinoma of the Bronchus
- Sarcoidosis
- Further Reading
- CHAPTER 4 Gastroenterology
- Vomiting
- Hiccups
- Weight Loss
- Dysphagia
- Constipation
- Diarrhoea
- Abdominal Pain
- Gastro-Oesophageal Reflux Disease (GORD)
- Barrett Oesophagus
- Peptic Ulcer Disease
- Iron Deficiency Anaemia
- Rectal Bleeding
- Family History of Colon Cancer
- Functional Bowel Disease
- Pseudomembranous Colitis
- Food Poisoning: E. coli O157
- Typhoid
- Further Reading
- CHAPTER 5 Liver and Biliary Tract Disorders
- Abnormal Liver Biochemistry
- Jaundice
- Acute Liver Disease
- Ascites
- Haematemesis and Melaena
- Nonalcoholic Fatty Liver Disease (NAFLD)
- Liver Failure
- Excess Alcohol Use
- Cholecystitis
- Acute Cholangitis
- Further Reading
- CHAPTER 6 Kidney and Urinary Tract Disease
- Presentation of Kidney and Urinary Tract Disease
- Fluid Balance and Electrolytes: Assessing Fluid Status
- Fluid Balance and Electrolytes: Sodium
- Low Urine Output
- Acute Heart Failure
- Hyperkalaemia
- The Acidotic Patient
- Acute Kidney Injury
- Chronic Kidney Disease
- Multisystem Vasculitis/Acute Glomerulonephritis
- Intercurrent Illness in Dialysis and Transplant Patients
- Nephrotic Syndrome
- Haematuria Without Albuminuria
- Urinary Tract Infection (UTI)
- Renal and Ureteric Colic
- Further Reading
- CHAPTER 7 Neurologia
- Diplopia
- Acute Loss of Vision
- Gradual Loss of Vision
- Red Eye
- Bell’s Palsy
- Vertigo
- Stroke
- Subdural Haemorrhage
- Encephalitis
- Meningococcal Meningitis and Septicaemia
- Meningitis
- Brain Abscess
- Traumatic Brain Injury
- Severe Brain Injury
- Fits and Faints
- Headaches
- Falls
- Difficulty Walking
- Movement Disorders
- Parkinson’s Disease
- Multiple Sclerosis (MS)
- Guillain–Barré Syndrome
- Spinal Cord Compression
- Further Reading
- CHAPTER 8 Psychiatry
- Dementia
- Delirium Tremens
- Depression
- Suicide and Deliberate Self-Harm (DSH)
- Acute Anxiety
- Opiate Dependence
- The Disturbed Patient
- Further Reading
- CHAPTER 9 Rheumatology and Bone Disease
- Osteoarthritis (OA)
- Rheumatoid Arthritis (RA)
- Systemic Lupus Erythematosus (SLE) and Vasculitis
- Acute Autoimmune Rheumatic Disease
- Reactive Arthritis
- Crystal Arthritis
- Polymyalgia Rheumatica/Giant Cell Arteritis
- Polymyositis and Dermatomyositis
- Acute Back Pain
- Severe Back Pain/Osteoporosis
- Osteomyelitis
- Septic Arthritis
- Metabolic Bone Diseases
- Further Reading
- CHAPTER 10 Endocrinology and Diabetes
- Diabetes Mellitus
- Diabetic Ketoacidosis (DKA)
- Hyperosmolar Hyperglycaemic State
- Hypoglycaemic Coma
- The Sick Diabetic Patient
- Management of Diabetic Patients Presenting for Surgery
- The Diabetic Foot
- Diabetes in Pregnancy
- Cushing Syndrome
- Hyperthyroidism
- Amiodarone and Thyroid Function
- Hypothyroidism
- Addison Disease
- Patients on Steroids for Surgery
- Hypercalcaemia
- Severe Hypercalcaemia
- Hypocalcaemia
- Phaeochromocytoma and Paraganglioma
- Hypopituitarism
- Diabetes Insipidus
- Syndrome of Inappropriate Antidiuretic Hormone (SIADH)
- Further Reading
- CHAPTER 11 Haematology and Oncology
- Microcytic and Macrocytic Anaemia
- Haemolytic Anaemia
- Elevated Haemoglobin (Polycythaemia)
- Elevated White Blood Cell Count
- Elevated Platelet Count
- Platelet Disorders
- Bleeding Disorders
- Disseminated Intravascular Coagulation (DIC)
- Thrombosis
- Thrombosis and the Antiphospholipid Syndrome
- Sickle-Cell Disease
- Types of Sickle-Cell Disease
- Glucose-6-Phosphate Dehydrogenase Deficiency
- Direct Orally Active Anticoagulant Drugs (DOACs)
- Splenomegaly, Splenectomy and Hyposplenism
- Blood Transfusion
- Haematological Oncology
- Anaemia in Rheumatoid Arthritis, Chronic Kidney Disease and Liver Disease
- Anaemia in Cancer
- Infection/Sepsis
- Further Reading
- CHAPTER 12 Dermatology
- A Swollen Red Leg
- Leg Ulceration
- Generalised Rash or Eruption
- Pruritus
- Eczema
- Psoriasis
- Urticaria and Angio-Oedema
- Hereditary Angio-Oedema (HAE)
- Cutaneous Adverse Drug Reaction (ADR)
- Sun-Induced Rash
- Erythema Nodosum
- Shingles
- Skin Lesions (see Box 12.2)
- Further Reading
- CHAPTER 13 Infectious Diseases
- Viral Infections
- Sepsis and Septic Shock
- Malaria
- Pyrexia of Unknown Origin (PUO)
- Epstein–Barr Virus
- Helminthic Infections/Parasitic Infections
- Further Reading
- CHAPTER 14 Sexually Transmitted Infections
- HIV/AIDS
- HIV and the Skin
- Vaginal Discharge
- Urethritis
- Anogenital Warts
- Further Reading
- CHAPTER 15 Care of the Elderly and Palliative Care
- Blackouts
- Falls in the Elderly
- Benign Paroxysmal Positional Vertigo (BPPV)
- Delirium
- Dementia
- Depression
- Nonspecific Presentation of Illness in the Elderly
- Appropriate Assessment Scales
- Stroke
- Heart Disease in the Elderly
- Transient Ischaemic Attack (TIA)
- Hypothermia
- Pressure Ulcers
- Urinary Tract Infection and Incontinence
- Arteritis
- Parkinson Disease (PD)
- Drugs as a Cause of Illness, Admission to Hospital and Delayed Discharge
- Do Not Attempt Resuscitation (DNAR) Decision-Making
- Palliative Care
- Further Reading
- Index
- Edition: 5
- Published: March 18, 2025
- Imprint: Elsevier
- No. of pages: 536
- Language: English
- Paperback ISBN: 9780443261893
- eBook ISBN: 9780443261909
PX
Philip Xiu
Philip Xiu a GP Registrar, Yorkshire Deanery, Leeds, UK.
Affiliations and expertise
GP Registrar, Yorkshire Deanery, Leeds, UKNA
Nicholas Aveyard
Nicholas Aveyard is Anaesthetic Registrar, Royal Devon University Healthcare NHS Foundation Trust NIHR Academic Clinical Fellow, University of Exeter.
Affiliations and expertise
Anaesthetic Registrar, Royal Devon University Healthcare NHS Foundation Trust NIHR Academic Clinical Fellow, University of Exeter, UK