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Klotho

  • 1st Edition, Volume 101 - April 25, 2016
  • Latest edition
  • Editor: Gerald Litwack
  • Language: English

Klotho is the latest edition of a series first published in 1943 on Vitamins and Hormones and the longest-running serial published by Academic Press. It provides up-to-date infor… Read more

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Description

Klotho is the latest edition of a series first published in 1943 on Vitamins and Hormones and the longest-running serial published by Academic Press. It provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic, with volumes focusing on a single molecule or on a disease that is related to vitamins or hormones that are interpreted broadly so that related substances, such as transmitters, cytokines, growth factors, and others can be reviewed.

Key features

  • Contains contributions from experts in the field of vitamins and hormones
  • Covers a vast array of subjects
  • In-depth, current information at the molecular to clinical levels

Readership

Researchers, faculty, and graduate students interested in cutting-edge reviews concerning the molecular and cellular biology of vitamins, hormones, and related factors and co-factors. Libraries and laboratories at institutes with strong programs in cell biology, biochemistry, molecular biology, gene regulation, hormone control, and signal transduction are likely to be interested.

Table of contents

1. Klotho-Related Protein KLrP: Structure and FunctionsYasuhiro Hayashi and Makoto Ito2. The FGF21 Receptor Signaling Complex: KLOTHO, FGFR1c and Other Regulatory InteractionsDawn M. Kilkenny and Jonathan V. Rocheleau3. Klotho-Dependent Cellular Transport RegulationMentor Sopjani and Miribane Dërmaku-Sopjani4. Klotho and the Growth Hormone/Insulin-like Growth Factor 1 Axis: Novel Insights Into Complex InteractionsTami Rubinek and Dalit Modan-Moses 5. Klotho Prevents Translocation of NFκBPaula Buendía, Rafael Ramírez, Pedro Aljama and Julia Carracedo6. The FGF23/KLOTHO Regulatory Network and its Roles in Human DisordersSaori Kinoshita and Masanobu Kawai7. MicroRNA-34a and Impaired FGF19/21 Signaling in ObesityTing Fu and Jongsook Kim Kemper8. The Role of Alpha-Klotho as a Universal Tumor SuppressorTami Rubinek and Ido Wolf9. Klotho is a Neuroprotective and Cognition-Enhancing ProteinCarmela R. Abraham, Patrick C. Mullen, Tracey Tucker Zhou, Cidi Chen and Ella Zeldich10. Function and Change with Aging of α-Klotho in the KidneyKeiko Akasaka-Manya, Hiroshi Manya and Tamao Endo11. αKlotho and Chronic Kidney DiseaseJavier A. Neyra and Ming Chang Hu12. Deficiency of Soluble α-Klotho as an Independent Cause of Uremic CardiomyopathyJian Xie, Yueh-Lin Wu and Chou-Long Huang

Product details

  • Edition: 1
  • Latest edition
  • Volume: 101
  • Published: April 27, 2016
  • Language: English

About the editor

GL

Gerald Litwack

Dr. Litwack has authored 3 textbooks on biochemistry and hormones (one with John Wiley & Sons and 2 with Academic Press/Elsevier) and he has edited more than 70 volumes in the Vitamins & Hormones series (Academic Press/Elsevier); he has edited 14 volumes entitled Biochemical Actions of Hormones (Academica Press); He has edited (with David Kritchevsky) Actions of Hormones on Molecular Processes (Academic Press)

Affiliations and expertise
Emeritus Founding Chair and Professor, Geisinger Commonwealth School of Medicine, United States Emeritus Professor, Rutgers University, United States

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