Kelley's Textbook of Rheumatology
Expert Consult Premium Edition - Enhanced Online Features and Print, 2-Volume Set
- 9th Edition - September 21, 2012
- Latest edition
- Authors: Gary S. Firestein, Ralph C. Budd, Sherine E Gabriel, Iain B. McInnes, James R. O'Dell
- Language: English
Kelley's Textbook of Rheumatology delivers the state-of-the-art scientific and clinical know-how you need to offer your patients the most effective diagnosis and care. This rh… Read more
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Kelley's Textbook of Rheumatology delivers the state-of-the-art scientific and clinical know-how you need to offer your patients the most effective diagnosis and care. This rheumatology book’s sweeping updates highlight current advances and breakthroughs that impact your practice. With Kelley's Textbook of Rheumatology, you'll be ready to handle the toughest clinical challenges you face.
- Search the entire contents online at www.expertconsult.com, download all of images, and watch videos demonstrating the complete musculoskeletal exam, including abnormal findings and the arthroscopic presentation of diseased joints.
- Review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance with the integrated chapter format that readers of Kelley's Textbook of Rheumatology have always appreciated.
- Gain a thorough understanding of the "whys" and "hows" of rheumatic disease management with detailed coverage of the very latest breakthroughs and the newest clinical algorithms.
Rheumatologists
Orthopedics
VOLUME I
STRUCTURE AND FUNCTION OF
BONE, JOINTS, AND CONNECTIVE
TISSUE, 1
1
Biology of the Normal Joint, 12
Synovium, 203
Cartilage and Chondrocytes, 334
Biology, Physiology, and Morphologyof Bone, 61
5
Muscle: Anatomy, Physiology,and Biochemistry, 67
6
Biomechanics, 797
Regenerative Medicine and TissueEngineering, 90
8
Proteinases and MatrixDegradation, 97
CELLS INVOLVED IN
AUTOIMMUNE DISEASES
AND INFLAMMATION, 117
9
Dendritic Cells, 11710
Mononuclear Phagocytes in RheumaticDiseases, 134
11
Neutrophils, 15212
Eosinophils, 17013
T Lymphocytes, 17414
B Cells, 19115
Fibroblasts and Fibroblast-likeSynoviocytes, 215
16
Mast Cells, 23217
Platelets, 245EFFECTOR MECHANISMS IN
AUTOIMMUNITY AND
INFLAMMATION, 255
18
Innate Immunity, 25519
Adaptive Immunity and Organization of LymphoidTissues, 268
20
Autoimmunity, 28121
Genetics of Rheumatic Diseases, 29922
Epigenetics, 31623
Complement System, 32524
Prostaglandins, Leukotrienes, and RelatedCompounds, 340
25
Cell Recruitment and Angiogenesis, 35826
Cytokines, 36927
Cell Survival and Death in RheumaticDiseases , 382
28
Experimental Models for RheumatoidArthritis, 400
29
Neural Regulation of Pain and Infl ammation, 413BROAD ISSUES IN THE APPROACH TO
RHEUMATIC DISEASE, 431
30
Principles of Epidemiology in RheumaticDisease, 431
31
Economic Burden of RheumaticDiseases, 440
32
Clinical Trial Design and Analysis, 45233
Assessment of Health Outcomes, 46234
Biologic Markers, 47635
Occupational and Recreational MusculoskeletalDisorders, 493
36
Cardiovascular Risk in RheumaticDisease, 505
37
Cancer Risk in Rheumatic Diseases, 51538
Introduction to Physical Medicine, PhysicalTherapy, and Rehabilitation, 528
39
Pregnancy in the Rheumatic Diseases, 540EVALUATION OF GENERALIZED AND
LOCALIZED SYMPTOMS, 559
40
History and Physical Examination of theMusculoskeletal System, 559
41
Acute Monoarthritis, 57742
Polyarticular Arthritis, 58743
The Skin and Rheumatic Diseases, 59944
The Eye and Rheumatic Diseases, 617DIFFERENTIAL DIAGNOSIS OF REGIONAL
AND DIFFUSE MUSCULOSKELETAL
PAIN, 625
45
Neck Pain, 62546
Shoulder Pain, 63947
Low Back Pain, 66548
Hip and Knee Pain, 68349
Foot and Ankle Pain, 70050
Hand and Wrist Pain, 70851
Temporomandibular Joint Pain, 72152
Fibromyalgia, 733DIAGNOSTIC TESTS AND PROCEDURES IN
RHEUMATIC DISEASES, 753
53
Synovial Fluid Analyses, Synovial Biopsy,and Synovial Pathology , 753
54
Arthrocentesis and Injection of Joints and SoftTissue, 770
55
Antinuclear Antibodies, 78956
Autoantibodies in Rheumatoid Arthritis, 80457
Acute Phase Reactants and the Conceptof Infl ammation, 818
58
Imaging Modalities in Rheumatic Diseases , 830PHARMACOLOGY OF ANTIRHEUMATIC
DRUGS, 871
59
Prostanoid Biology and Its TherapeuticTargeting, 871
60
Glucocorticoid Therapy, 89461
Traditional DMARDs: Methotrexate, Lefl unomide,Sulfasalazine, Hydroxychloroquine, and
Combination Therapies, 917
62
Immunosuppressive Drugs, 94163
Anticytokine Therapies, 95764
Cell-Targeted Biologics and Targets:Rituximab, Abatacept, and Other
Biologics, 978
65
Antihyperuricemic Agents, 100166
Analgesic Agents in RheumaticDisease, 1014
67
Psychosocial Management of RheumaticDiseases, 1034
68
Nutrition and Rheumatic Diseases, 1044VOLUME II
RHEUMATOID ARTHRITIS, 1059
69
Etiology and Pathogenesis of RheumatoidArthritis , 1059
70
Clinical Features of RheumatoidArthritis , 1109
71
Treatment of Rheumatoid Arthritis, 113772
Early Synovitis and Early UndifferentiatedArthritis, 1161
73
Sjögren’s Syndrome, 1169SPONDYLOARTHROPATHIES, 1193
74
Pathogenesis of Ankylosing Spondylitis andReactive Arthritis, 1193
75
Ankylosing Spondylitis, 120276
Reactive Arthritis and UndifferentiatedSpondyloarthritis, 1221
77
Psoriatic Arthritis, 123278
Enteropathic Arthritis, 1251SYSTEMIC LUPUS ERYTHEMATOSUS AND
RELATED SYNDROMES, 1269
79
Etiology and Pathogenesis of Systemic LupusErythematosus, 1269
80
Clinical Features of Systemic LupusErythematosus, 1283
81
Treatment of Systemic LupusErythematosus, 1304
82
Antiphospholipid Syndrome, 1331SCLERODERMA, INFLAMMATORY
MYOPATHIES, AND OVERLAP
SYNDROMES, 1343
83
Etiology and Pathogenesis of Scleroderma, 134384
Clinical Features and Treatment ofScleroderma, 1366
85
Infl ammatory Diseases of Muscle and OtherMyopathies, 1404
86
Overlap Syndromes, 1431VASCULITIS, 1453
87
Classifi cation and Epidemiology of SystemicVasculitis, 1453
88
Giant Cell Arteritis, Polymyalgia Rheumatica, andTakayasu’s Arteritis, 1461
89
Antineutrophil Cytoplasm Antibody–AssociatedVasculitis, 1481
90
Polyarteritis Nodosa and Related Disorders, 149891
Immune Complex–Mediated Small VesselVasculitis, 1508
92
Primary Angiitis of the Central NervousSystem, 1518
93
Behçet’s Disease, 1525CRYSTAL-INDUCED AND
INFLAMMASOME-MEDIATED
INFLAMMATION, 1533
94
Etiology and Pathogenesis of Hyperuricemiaand Gout , 1533
95
Clinical Features and Treatment of Gout, 155496
Calcium Crystal Disease: CalciumPyrophosphate Dihydrate and Basic
Calcium Phosphate , 1576
97
Familial Autoinfl ammatory Syndromes, 1597CARTILAGE, BONE, AND HERITABLE
CONNECTIVE TISSUE DISORDERS, 1617
98
Pathogenesis of Osteoarthritis, 161799
Clinical Features of Osteoarthritis, 1636100
Treatment of Osteoarthritis , 1646101
Metabolic Bone Disease, 1660102
Proliferative Bone Diseases, 1680103
Osteonecrosis, 1692104
Relapsing Polychondritis , 1712105
Heritable Diseases of Connective Tissue, 1719RHEUMATIC DISEASES OF
CHILDHOOD, 1741
106
Etiology and Pathogenesis of JuvenileIdiopathic Arthritis, 1741
107
Treatment of Juvenile Idiopathic Arthritis, 1752108
Pediatric Systemic Lupus Erythematosus,Dermatomyositis, Scleroderma, and
Vasculitis, 1771
INFECTION AND ARTHRITIS, 1801
109
Bacterial Arthritis, 1801110
Lyme Disease, 1815111
Mycobacterial Infections of Bonesand Joints, 1829
112
Fungal Infections of Bones andJoints, 1841
113
Rheumatic Manifestations of HumanImmunodefi ciency Virus Infection, 1851
114
Viral Arthritis, 1865115
Poststreptococcal Arthritis and RheumaticFever, 1875
ARTHRITIS ACCOMPANYING
SYSTEMIC DISEASE, 1889
116
Amyloidosis, 1889117
Sarcoidosis , 1898118
Hemochromatosis, 1907119
Hemophilic Arthropathy, 1915120
Rheumatologic Manifestations ofHemoglobinopathies, 1924
121
Endocrine Diseases and the MusculoskeletalSystem, 1927
122
Musculoskeletal Syndromes in Malignancy, 1934123
Tumors and Tumor-like Lesions of Joints andRelated Structures, 1951
"The ninth edition has many positive changes, including in the presentation, such as color coding of sections and charts and diagrams, which have made the information easier to assimilate. The book also provides up-to-date information while keeping with the traditional feel of previous editions. In times where electronic media have taken over print media, <B><I>Kelley's</I></B> still draws readers. It is likely the most definitive rheumatology book not only in the U.S., but also in the rest of the world".- Deepali P Sen, M.D.(Washington University Medical Center) Doody 5 star review!
- Edition: 9
- Latest edition
- Published: September 21, 2012
- Language: English
GF
Gary S. Firestein
Gary Firestein, MD, is a board-certified rheumatologist who diagnoses and treats patients with autoimmune conditions as well as diseases of the joints, muscles and bones. A professor at UC San Diego School of Medicine, Dr. Firestein is distinguished for his research and serves as director of the Altman Clinical and Translational Research Institute and the senior associate vice chancellor for health sciences. Dr. Firestein's research interest focuses on the pathogenesis and treatment of rheumatoid arthritis.
Dr. Firestein is the recipient of many awards and honors, including the Arthritis Foundation's Jane Wyman Humanitarian Award in 2010 for his contributions to rheumatology; the Arthritis Foundation Lee C. Howley Sr. Prize for Arthritis Research; and the American College of Rheumatology Distinguished Investigator Award. He has been elected to the American Society for Clinical Investigation and the Association of American Physicians. He has served as an editor for the Textbook of Rheumatology for since the 7th edition (2004).
Affiliations and expertise
Distinguished Professor of Medicine, Senior Associate Vice Chancellor for Health Sciences, Director, Altman Clinical and Translational Research Institute, USARB
Ralph C. Budd
Affiliations and expertise
Professor of Medicine and Microbiology and Molecular Genetics, Director, Vermont Center for Immunology and Infectious Diseases, University of Vermont College of Medicine Distinguished University Professor, The University of Vermont College of Medicine, Burlington, VermontSG
Sherine E Gabriel
Affiliations and expertise
Professor and Dean, Rutgers Robert Wood Johnson Medical School, CEO, Robert Wood Johnson Medical Group, Emeritus Professor, Mayo Clinic, New Brunswick, New JerseyIM
Iain B. McInnes
Iain McInnes is Director of the Institute of Infection, Immunity and Inflammation at the University of Glasgow, UK. He has extensive experience in leading multicenter programs nationally and internationally. He is Director of the Scottish MRC Clinical Pharmacology and Pathology Clinical PhD Training Program, Chief Investigator for the Scottish Early RA Cohort (SERA) and the related SMS-IC biomarker discovery program (PROMISERA), and chief investigator of numerous global phase II and III clinical trials of novel immune therapies. He has served as member or chair of numerous national grant-funding panels and as chair of several European League Against Rheumatism (EULAR) scientific committees – he is now Treasurer and President Elect of EULAR serving on its Steering Committee. He is formerly Chairman of the Foundation for European Rheumatology Research (Foreum) Scientific Committee and leads the EULAR-supported European Roadmap Program that is defining the research agenda for rheumatology for the next decade.
Affiliations and expertise
Muirhead Professor of Medicine, Arthritis Research UK Professor of Rheumatology, Director of Institute of Infection,Immunity, and Inflammation, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, Scotland, United KingdomJO
James R. O'Dell
James R. O’Dell, MD is the Stokes Shackleford Professor of Internal Medicine, Vice-Chairman of Internal Medicine and Chief of the Division of Rheumatology at the University of Nebraska Medical Center (UNMC) in Omaha. Dr. O’Dell founded and has directed the Rheumatoid Arthritis Investigational Network (RAIN) for the last 25 years. Dr. O’Dell is the PI of the large multinational RA research study based at the VA through their cooperative studies program. Dr. O’Dell has published extensively, mostly in the area of rheumatoid arthritis. He has presented frequently at national and international meetings and has more than 100 published articles in top-level rheumatology journals. He has served on numerous American College of Rheumatology (ACR) committees over the last 20 years, including time on both the ACR and REF BOD, as well as a two-year term as President of the Research and Education Foundation of the ACR and was President of the College (2011-2012). Additionally, he is Editor-in-Chief of Up To Date for Rheumatology.
Affiliations and expertise
Bruce Professor and Vice Chairman of Internal Medicine, University of Nebraska Medical Center, Chief of Rheumatology, Department of Medicine, Omaha Veterans Affairs, Omaha, Nebraska, USARead Kelley's Textbook of Rheumatology on ScienceDirect