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Elsevier

Kelley and Firestein's Textbook of Rheumatology, 2-Volume Set

  • 10th Edition - June 21, 2016
  • Latest edition
  • Authors: Gary S. Firestein, Ralph C. Budd, Sherine E Gabriel, Iain B. McInnes, James R. O'Dell
  • Language: English

Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firest… Read more

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Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein’s Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases.

Key features

  • An ideal bal
    • ance of the basic science you need to know and how to apply that information to clinical practice.

  • An integrated chapter format

    •  allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes.

  • Videos online

    •  demonstrate the complete musculoskeletal exam, including abnormal findings and the arthroscopic presentation of diseased joints.

Table of contents

1 Biology of the Normal Joint

2 Synovium

3 Cartilage and Chondrocytes

4 Biology, Physiology, and Morphology of Bone

5 Muscle: Anatomy, Physiology, and Biochemistry

6 Biomechanics

7 Tissue Engineering

8 Proteinases and Matrix Degradation

9 Dendritic Cells

10 MACROPHAGES

11 Neutrophils

12 T Lymphocytes

13 B Cells

14 Fibroblasts and Fibroblast-like Synoviocytes

15 Mast Cells

16 Platelets and Rheumatic Diseases

17 Innate Immunity

18 ADAPTIVE IMMUNITY and Organization of Lymphoid Tissues

19 Autoimmunity

20 METABOLIC REGULATION IN IMMUNITY

21 Genetics of Rheumatic Diseases

22 Epigenetics of rheumatic diseases

23 Complement System

24 Prostaglandins, Leukotrienes, and Related Compounds

25 Cell Recruitment and Angiogenesis

26 Cytokines

27 PRINCIPLES OF SIGNALING

28 Cell Survival and Death in Rheumatic Diseases

29 Animal Models of Rheumatic Diseases

30 Neural regulation of Pain and Inflammation

31 RESEARCH METHODS IN THE RHEUMATIC DISEASES

32 BURDEN OF THE RHEUMATIC DISEASE

33 Assessment of Health Outcomes IN RHEUMATIC DISEASES

34 Biologic Markers

35 Occupational and Recreational MSK Disorders

36 Cardiovascular Risk in Rheumatic Disease

37 Cancer Risk in Rheumatic Diseases

38 Introduction to Physical Medicine, Physical Therapy and Rehabilitation

39 Pregnancy and Rheumatic Diseases

40 History and Physical Examination of the Musculoskeletal System

41 EVALUATION AND DIFFERENTIAL DIAGNOSIS OF Monoarticular Arthritis

42 EVALUATION AND DIFFERENTIAL DIAGNOSIS OF Polyarticular Arthritis

43 The Skin and Rheumatic Diseases

44 The Eye and Rheumatic Diseases

45 Neck Pain

46 Shoulder Pain

47 Low Back Pain

48 Hip and Knee Pain

49 Ankle and Foot Pain

50 Hand and Wrist Pain

51 Temporomandibular Joint Pain

52 Fibromyalgia

53 Synovial Fluid Analysis, Synovial Biopsy, and Synovial Pathology

54 Arthrocentesis and Injection of Joints and Soft Tissue

55 Antinuclear Antibodies

56 Autoantibodies in rheumatoid arthritis

57 Acute Phase Reactants

58 Imaging Modalities in Rheumatic Disease

59 Prostanoid Biology and its Therapeutic Targeting

60 Glucocorticoid Therapy

61 Traditional DMARDS: Methotrexate, Leflunomide, Sulfasalazine, and Hydroxychloroquine and Combination Therapies

62 TRADITIONAL Immunoregulatory Drugs

63 Anticytokine Therapies

64 Cell Targeted Biologics

65 NOVEL INTRACELLULAR TARGETING AGENTS

66 Urate Lowering Therapy

67 Analgesic Agents in Rheumatic Diseases

68 Nutrition and Rheumatic Disease

69 Etiology and Pathogenesis of Rheumatoid Arthritis

70 Clinical Features of Rheumatoid Arthriti

71 Treatment of Rheumatoid Arthritis

72 Early Synovitis and Early Undifferentiated Arthritis

73 Sjogren's Syndrome

74 Etiology and Pathogenesis of Spondyloarthropathies

75 Ankylosing Spondylitis

76 Undifferentiated Spondyloarthritis and Reactive Arthritis

77 Psoriatic Arthritis

78 Enteropathic Arthritis

79 Etiology and Pathogenesis of SLE

80 Clinical Features of SLE

81 Treatment of SLE

82 Antiphospholipid Syndrome

83 Etiology and Pathogenesis of Scleroderma

84 Clinical Features and Treatment of Scleroderma

85 Inflammatory Diseases of Muscle and Other Myopathies

86 Overlap Syndromes

87 Classification and Epidemiology of Systemic Vasculitis

88 Giant Cell Arteritis, Polymyalgia Rheumatica, and Takayasu's Arteritis

89 Antineutrophil Cytoplasmic Antibody-Associated Vasculitis

90 Polyarteritis and Related Disorders

91 Immune Complex-Mediated Small Vessel Vasculitis

92 Isolated Angiitis of the Nervous System

93 Bechet's Disease

94 Etiology and Pathogenesis of Gout and Hyperuricemia

95 Clinical Features and Treatment of Gout

96 Calcium Crystal Diseases: Calcium Pyrophosphate Dihydrate and Basic Calcium Phosphate

97 Familial Autoinflammatory Syndromes

98 Etiology and Pathogenesis of Osteoarthritis

99 Clinical Features of Osteoarthritis

100 Treatment of Osteoarthritis

101 Metabolic Bone Disease

102 Proliferative Bone Disease

103 Osteonecrosis

104 Relapsing Polychondritis

105 Heritable Diseases of Connective Tissue

106 Etiology and Pathogenesis of Juvenile Idiopathic Arthritis

107 Treatment of Juvenile Inflammatory Arthritis

108 SLE, Juvenile Dermatomyositis, Scleroderma and Vasculitis

109 Bacterial Arthritis

110 Lyme Disease

111 Mycobacterial Infections of Bones and Joints

112 Fungal Infections of Bones and Joints

113 Rheumatic Manifestations of HIV Infection

114 Viral Arthritis

115 Rheumatic Fever and Post-Streptococcal Arthritis

116 Amyloidosis

117 Sarcoidosis

118 Hemachromotosis

119 Hemophilic Arthropathy

120 Rheumatic Manifestations of Hemoglobinopathies

121 IgG4-RELATED DISEASES

122 Arthritis Accompanying Endocrine and Metabolic Disorders

123 Musculoskeletal Syndromes Associated with Malignancy

124 Tumors and Tumor-like Lesions of Joints and Related Structures

Review quotes

"an excellent 2-volume series ... I would highly recommend this book for rheumatology residents ... and practicing rheumatologists ... given its thorough yet succinct delivery of many topics"

"As a highly specialised text it ticks every box, and the editors should be commended"

"It is a tour de force in terms of knowledge and effort. This edition will retain a wide appeal among all those studying rheumatology. In addition, its high standing reputation for unambiguous advice will continue to make this textbook the reference of choice for practicing rheumatologists."

-Tamer A Gheita, MD (Professor of Rheumatology, Faculty of Medicine, Cairo University)

Product details

  • Edition: 10
  • Latest edition
  • Published: September 1, 2016
  • Language: English

About the authors

GF

Gary S. Firestein

Gary Firestein, MD, is a board-certified rheumatologist who diagnoses and treats patients with autoimmune conditions as well as diseases of the joints, muscles and bones. A professor at UC San Diego School of Medicine, Dr. Firestein is distinguished for his research and serves as director of the Altman Clinical and Translational Research Institute and the senior associate vice chancellor for health sciences. Dr. Firestein's research interest focuses on the pathogenesis and treatment of rheumatoid arthritis. Dr. Firestein is the recipient of many awards and honors, including the Arthritis Foundation's Jane Wyman Humanitarian Award in 2010 for his contributions to rheumatology; the Arthritis Foundation Lee C. Howley Sr. Prize for Arthritis Research; and the American College of Rheumatology Distinguished Investigator Award. He has been elected to the American Society for Clinical Investigation and the Association of American Physicians. He has served as an editor for the Textbook of Rheumatology for since the 7th edition (2004).
Affiliations and expertise
Distinguished Professor of Medicine, Senior Associate Vice Chancellor for Health Sciences, Director, Altman Clinical and Translational Research Institute, USA

RB

Ralph C. Budd

Affiliations and expertise
Professor of Medicine and Microbiology and Molecular Genetics, Director, Vermont Center for Immunology and Infectious Diseases, University of Vermont College of Medicine Distinguished University Professor, The University of Vermont College of Medicine, Burlington, Vermont

SG

Sherine E Gabriel

Affiliations and expertise
Professor and Dean, Rutgers Robert Wood Johnson Medical School, CEO, Robert Wood Johnson Medical Group, Emeritus Professor, Mayo Clinic, New Brunswick, New Jersey

IM

Iain B. McInnes

Iain McInnes is Director of the Institute of Infection, Immunity and Inflammation at the University of Glasgow, UK. He has extensive experience in leading multicenter programs nationally and internationally. He is Director of the Scottish MRC Clinical Pharmacology and Pathology Clinical PhD Training Program, Chief Investigator for the Scottish Early RA Cohort (SERA) and the related SMS-IC biomarker discovery program (PROMISERA), and chief investigator of numerous global phase II and III clinical trials of novel immune therapies. He has served as member or chair of numerous national grant-funding panels and as chair of several European League Against Rheumatism (EULAR) scientific committees – he is now Treasurer and President Elect of EULAR serving on its Steering Committee. He is formerly Chairman of the Foundation for European Rheumatology Research (Foreum) Scientific Committee and leads the EULAR-supported European Roadmap Program that is defining the research agenda for rheumatology for the next decade.
Affiliations and expertise
Muirhead Professor of Medicine, Arthritis Research UK Professor of Rheumatology, Director of Institute of Infection,Immunity, and Inflammation, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, Scotland, United Kingdom

JO

James R. O'Dell

James R. O’Dell, MD is the Stokes Shackleford Professor of Internal Medicine, Vice-Chairman of Internal Medicine and Chief of the Division of Rheumatology at the University of Nebraska Medical Center (UNMC) in Omaha. Dr. O’Dell founded and has directed the Rheumatoid Arthritis Investigational Network (RAIN) for the last 25 years. Dr. O’Dell is the PI of the large multinational RA research study based at the VA through their cooperative studies program. Dr. O’Dell has published extensively, mostly in the area of rheumatoid arthritis. He has presented frequently at national and international meetings and has more than 100 published articles in top-level rheumatology journals. He has served on numerous American College of Rheumatology (ACR) committees over the last 20 years, including time on both the ACR and REF BOD, as well as a two-year term as President of the Research and Education Foundation of the ACR and was President of the College (2011-2012). Additionally, he is Editor-in-Chief of Up To Date for Rheumatology.
Affiliations and expertise
Bruce Professor and Vice Chairman of Internal Medicine, University of Nebraska Medical Center, Chief of Rheumatology, Department of Medicine, Omaha Veterans Affairs, Omaha, Nebraska, USA

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