Isozymes

Organizing Committee

List of Contributors

Preface

Acknowledgments

Biology of Isozymes

Biochemistry of Isozymes

Multiple Forms of Mammalian DNA-Dependent DNA Polymerases

The RNA Polymerases of the Nucleus and Chloroplasts of Maize

The RNA Polymerases of Fungi. Glutarimides and the Regulation of RNA Polymerase I.

RNA Polymerase II of Escherichia coli

The Role of Subunit Interactions in the Genesis of Non-binomial Lactate Dehydrogenase Isozyme Distributions

Subunit Interaction in Lactate Dehydrogenase

A Structural Comparison of Porcine B4 and Dogfish A4 Isozymes of Lactate Dehydrogenase

The Two-Stage Reversible Denaturation of Lactate Dehydrogenase at Low pH

Mechanism of Isozyme Formation as Related to Subunit Interactions

Biochemical and Genetic Studies of Peroxisomal Multiple Enzyme Systems: α-Hydroxyacid Oxidase and Catalase

Studies on the Electrophoretic Variants of Human Hypoxanthine-Guanine Phosphoribosyltransferase

Heterogeneity of Human Erythrocyte Catalase

Affinity Chromatography Resolution of Plasminogen Isozymes

Multiple Molecular Forms of Transglutaminases in Human and Guinea Pig

The Isozymes of Two Human Adipose Tissue Lipolytic Activities

New Chromatographie Approaches to the Separation of Human Alkaline Phosphatase Isozymes

Alkaline Phosphatase Isozymes in the Alimentary Canal of the Silkworm

Differences in the Structure, Function, and Formation of Two Isozymes of Escherichia coli Alkaline Phosphatase

Hormonally Induced Modification of HeLa Alkaline Phosphatase with Increased Catalytic Activity

Genetic and Non-genetic Variation of Human Acid Phosphatases

Phosphoglucomutase Isozymes Caused by Sulfhydryl Oxidation

Carboxylesterase Isozymes in the Rabbit Liver: Physicochemical Properties

Structural Classes of Jackbean Urease Variants and Their Relation to a Structural Classification of Isozymes

Rat Liver Tyrosine Aminotransferase: Problems of Interpreting Changes in Multiple Form Patterns

Molecular Forms of Hepatic Tyrosine Aminotransferase Activity

The Different Origins of Multiple Molecular Forms of Phosphoglucose Isomerase

Nature of the Multiple Forms of Glucosephosphate and Triosephosphate Isomerases

The Use of Thiol Reagents in the Analysis of Isozyme Patterns

Sulfhydryl Oxidation and Multiple Forms of Human Erythrocyte Pyruvate Kinase

Bovine and Chicken Pyruvate Kinase Isozymes Intraspecies and Interspecies Hybrids

Properties of Rat Pyruvate Kinase Isozymes

Multiple Molecular Forms of Neurospora Mitochondrial Malate Dehydrogenase

Structural Relationship of Human Erythrocyte Carbonic Anhydrase Isozymes B and C

Multiplicity of Isozymes of Lipoamide Dehydrogenase and Phospholipase A

Properties of Multiple Molecular Forms of Lipoamide Dehydrogenase

Multiple Forms of ß-Glucuronidase: Molecular Nature, Transformation, and Subcellular Translocation

Gel Isoelectric Focusing and the Microheterogeneity of Human Glucose-6-Phosphate Dehydrogenase

Investigations on the Quaternary Structure and Function of Oligomeric Proteins by Hybridization with Variants Produced by Chemical Modification

Radiochemical Assay of Electrophoretically Separated Phosphotransferases Using Lanthanum Precipitation

Presence of a Diphosphoglycerate Phosphatase Activity in the Multiple Molecular Forms of 3-Phosphoglycerate Mutase

Heterogeneity, Polymorphism, and Substrate Specificity of Alcohol Dehydrogenase from Horse Liver

Drosophila Alcohol Dehydrogenase: Origin of the Multiple Forms

Multiple Molecular Forms of Pneumococcal Neuraminidase

Isozymes of the Pentose Phosphate Pathway

Post-Translational Alterations of Human Erythrocyte Enzymes

A New Purification Procedure for Pig Heart Fumarase

Multiple Forms of Pig Heart and Herellea vaginicola Succinate Thiokinase, Effects of Sulfhydral Groups and Ligands

Subtilisin-Like Isozyme in Pronase

Implications of Macromolecule-Small Molecule Interactions and Kinetically Controlled Reactions for Separation of Proteins by Mass Transport

Index