Ion Chromatography
Instrumentation, Techniques and Applications
- 1st Edition, Volume 13 - August 27, 2021
- Editors: Christopher A. Pohl, Satinder Ahuja, Nebojsa Avdalovic, Kannan Srinivasan
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 1 3 0 7 5 - 9
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 3 0 7 6 - 6
Ion Chromatography: Instrumentation, Techniques and Applications, Volume 13 in the series Separation Science and Technology, provides a modern overview of all aspects of ion c… Read more
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Request a sales quoteIon Chromatography: Instrumentation, Techniques and Applications, Volume 13 in the series Separation Science and Technology, provides a modern overview of all aspects of ion chromatography instrumentation and chemistry techniques, including the historical backdrop of some of the key developments. Most existing books on ion chromatography are focused on single column ion chromatography (rarely used today) or applications, or are outdated. This book covers the broad range of technologies in use and explains the advantages of each, helping both experienced and new practitioners to choose the method they need.
The editors of this book have all played a key role in the success of ion chromatography at Dionex Corporation, the undisputed leader in ion chromatography for more than 40 years, and are in a unique position to describe both the technology and its applications. Ion chromatography is the technique of choice for analyzing ionic or ionizable compounds in various industries, such as pharmaceuticals and food. In addition, it is very useful for monitoring cationic or anionic impurities in drinking water.
- Covers the broad range of technologies currently used in ion chromatography, with an explanation of not only how the technology works, but also which commonly used approaches represent the best options
- Provides a solid introduction for new practitioners to improve background knowledge on troubleshooting skills
- Serves as a comprehensive overview of all approaches in ion chromatography, describing the advantages of various newer technology options over older methodologies still in wide use
Analytical chemists who are either new to the subject or need a refresher on the current technology
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Contributors
- Preface
- Foreword
- Chapter 1: The invention and early development of ion chromatography
- Abstract
- The resin-clumping problem
- 1971—Breakthrough
- A new route to low capacity anion exchangers
- 1972–73 expansion and acceptance
- Colloidal form anion exchangers
- The carbonate eluent system
- Patenting and licensing
- Dow research post-1975
- Intangibles
- Chapter 2: Stationary phases and suppressors in ion chromatography, 1975–2000
- Abstract
- Conclusion
- Chapter 3: Stationary phases in ion chromatography
- Abstract
- Introduction
- Columns for separation of suppressor compatible cations
- Columns for separation of suppressor compatible anions
- Columns for separation of carbohydrates
- Mixed-mode columns
- Columns for separation of amino acids
- Columns for separation of transition metals
- Ion exclusion and Ion-exclusion phases
- Mobile phase ion chromatography (MPIC) and MPIC phases
- Column cleanup and regeneration
- Chapter 4: Suppressors in ion chromatography
- Abstract
- Introduction
- Flat membrane chemical suppressor
- Flat membrane electrolytic suppressor
- Suppressor practical use recommendations
- Suppressor form and continuous suppression
- Retention in the suppressor
- Dynamic suppression capacity
- Need for hydration
- Suppressor selection
- Suppressor installation
- Chemical suppressor operation
- Electrolytic suppressor operation
- Role of the sample matrix
- Conclusions
- Chapter 5: Electrolytic eluent generators and their applications in ion chromatography
- Abstract
- Introduction
- Earlier studies of electrochemistry involving ion-exchange membranes and resins
- Large-capacity electrolytic base and acid eluent generators
- Electrolytic salt eluent generators
- Higher pressure electrolytic eluent generators
- Capillary-scale electrolytic base and acid generators
- Continuously regenerated trap columns (CR-TC)
- RFIC systems and their applications
- A practical guide for successful use of eluent generator cartridges in RFIC systems
- Conclusions
- Chapter 6: Electrolysis-based accessories in ion chromatography
- Abstract
- Introduction
- CR-TC practical use recommendations
- Salt converter cation suppressor
- Salt converter practical use recommendations
- Electrolytic regenerant concentrator (ERC) for carbonate removal device (CRD)
- Electrolysis-based buffer generators
- Chapter 7: Eluent regeneration and ion reflux devices and their applications in ion chromatography
- Abstract
- Introduction
- Ion chromatography systems with eluent regeneration
- Ion chromatography systems with ion reflux
- Conclusions
- Chapter 8: A practical guide for carbohydrate determinations by high-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD)
- Abstract
- Introduction
- Liquid chromatography system for HPAE-PAD
- Eluents for HPAE-PAD
- Water
- Sodium hydroxide
- Sodium acetate
- Installation of eluents
- Eluent generation for hydroxide eluents
- Other eluents
- Column choice, installation, and care
- Electrochemical detector and cell
- Additional autosampler considerations
- Sample considerations
- Other considerations
- Common HPAE-PAD applications
- Monosaccharide analysis of glycoproteins
- Sialic acid analysis of glycoproteins
- Carbohydrate analysis of biofuel-related samples
- Glycoprotein asparagine-linked oligosaccharide profiling
- HPAE-PAD analysis of N-linked oligosaccharides coupled to mass spectrometry
- Summary
- Acknowledgment
- Chapter 9: Multidimensional techniques in ion chromatography
- Abstract
- Introduction
- Multidimensional approach practical use recommendations
- Chapter 10: A practical guide for amino acid determinations by high-performance anion-exchange chromatography with integrated pulsed amperometric detection
- Abstract
- Introduction
- Liquid chromatography system for AAA-Direct
- Eluents for AAA-Direct
- Column installation and care
- Installation of the electrochemical cell
- Applications
- Additional recommendations
- Chapter 11: Ion chromatography methods that use electrochemical detection
- Abstract
- Introduction
- Ion chromatography system for electrochemical detection methods
- Eluents for IC with electrochemical detection methods
- Column installation and care
- The electrochemical cell
- Applications
- Acknowledgments
- Chapter 12: Capillary ion chromatography
- Abstract
- Introduction
- Capillary ion chromatography system design
- Operation of capillary RFIC systems
- Capillary electrolytic eluent generators and continuously regenerated trap columns
- Capillary ion chromatography columns
- Capillary electrolytic suppressors
- Capillary IC applications
- A practical guide for successful use of capillary ion chromatography
- Conclusion
- Index
- No. of pages: 348
- Language: English
- Edition: 1
- Volume: 13
- Published: August 27, 2021
- Imprint: Academic Press
- Paperback ISBN: 9780128130759
- eBook ISBN: 9780128130766
CP
Christopher A. Pohl
Christopher has 40 years of experience with ion exchange chromatography and has worked for Dionex, the industry leader in this field, for more than 35 years where he has been actively involved in ion chromatography research and development. He holds more than 80 US patents with numerous foreign equivalents, most of which are related to the field of ion chromatography. He is author or co-author of more than 120 published articles and eight chapters.
Affiliations and expertise
Formerly DionexSA
Satinder Ahuja
Satinder Ahuja is a leading expert on water quality improvement. He earned his PhD in analytical chemistry from the University of the Sciences in Philadelphia. He worked for Novartis Corp. in various leadership positions for over 25 years and taught as an adjunct professor at Pace University for over 10 years. As president of Ahuja Consulting, he advises on water quality issues relating to chemicals and pharmaceuticals. A member of the executive committee of the Rivers of the World Foundation (ROW), Dr. Ahuja has organized numerous global symposia on improving water quality, including presentations for the American Chemical Society and UNESCO. Dr. Ahuja has published numerous papers and more than 25 books. His latest books are Contaminants in Our Water (ACS, 2020); Evaluating Water Quality to Prevent Future Disasters (Elsevier, 2019); Advances in Water Purification Techniques (Elsevier, 2019); and Chemistry and Water (Elsevier, 2017).
Affiliations and expertise
President, Ahuja Consulting for Water Quality, Calabash, NC, USANA
Nebojsa Avdalovic
Nebojsa worked for Dionex Corporation as a Vice President of R&D and Chief Science Officer from 1990 to 2005. Before that he was Director of the Molecular Structure Products Division of SmithKline Beckman organization. He joined SKB organization from academia. He served as a professor at the Wistar Institute, University of Pennsylvania in Philadelphia from 1975 to 1985. He graduated from Medical School and then obtained a Ph.D. in physiology and biochemistry. His primary activity was in molecular biology and chemical carcinogenesis while working in academia. After joining industry he worked mostly in analytical chemistry and biochemistry, and he published more than 100 papers in peer reviewed Journals and holds more than 40 US issued patents.
Affiliations and expertise
Formerly, Professor, Wistar Institute, University of Pennsylvania, Philadelphia, USAKS
Kannan Srinivasan
Kannan holds a BS and an MS in Chemistry from University of Mumbai, India and a Ph.D. in Analytical Chemistry from American University. Kannan has over 25 years of experience working with chemistry and separation sciences. His expertise is in the field of chromatography and associated detection methodologies, electrically driven processes, water purification and related monitoring technologies, and extraction and multi-dimensional separations. He has over 40 U.S. patents issued and many of his inventions are currently used in IC instruments and consumables.
Affiliations and expertise
Thermo Fisher Scientific, USARead Ion Chromatography on ScienceDirect