Preface. Structure and function of G protein coupled receptors, T. Jackson. Structure and function of G proteins, J. Olate & J. E. Allende. The regulation of adenylyl cyclase by receptor-operated G proteins, A. Levitzki & A. Bar-Sinai. Receptor regulation of phosphoinositidase C, T. F. J. Martin. Guanylyl cyclase-linked receptors, D. L. Garbers. Prostaglandin and thromboxane biosynthesis, W. L. Smith et al. Cyclic nucleotide-dependent protein kinases, J. D. Scott. Protein kinase C, S. Stabel & P. J. Parker. Structure and function of inositol trisphosphate receptors, C. W. Taylor & A. Richardson. Receptor-regulated calcium entry, J. W. Putney, Jr. Regulatory functions of calmodulin, A. R. Meens et al. Cyclic nucleotide phosphodiesterases: pharmacology, biochemistry and function, W. J. Thompson. Regulation of the metabolism of 1,2 -diacylglycerols and inositol phosphates that respond to receptor activation, S. B. Shears. Ca2+ extrusion across plasma membrane and Ca2+ uptake by intracellular stores, L. Missiaen et al. Organization of intracellular calcium signals generated by inositol lipid-dependent hormones, T. A. Rooney & A. P. Thomas. Calcium signalling and the triggering of secretion in adrenal chromaffin cells, T. R. Cheek. Intracellular messengers and the control of protein synthesis, S. J. Morley & G. Thomas. Acknowledgements. References. Index.