International Review of Cell and Molecular Biology

Series Page

Contributors

Chapter One. New Insights into Adhesion Signaling in Bone Formation

1 Introduction

2 Cell-Adhesion Receptors in Bone Cells

3 Lessons from Integrin and Integrin-Associated Proteins-Deficient Mice

4 Integrin-Dependent Signaling in Osteoblasts

5 Mechanotransduction in Bone Cells

6 Conclusion and Perspectives

Acknowledgments

References

Chapter Two. New Insights into Roles of Acidocalcisomes and Contractile Vacuole Complex in Osmoregulation in Protists

1 Introduction

2 Acidocalcisomes in Protists

3 Contractile Vacuole Complex

4 Volume Control in T. cruzi

5 Conclusions and Open Questions

Acknowledgments

References

Chapter Three. Functional Roles of Histone Modification, Chromatin Remodeling and MicroRNAs in Arabidopsis Flower Development

1 Introduction

2 Histone Modification in Flower Development

3 Chromatin Remodeling in Flower Development

4 Function of MicroRNAs in Flower Development

5 Concluding Remarks

References

Chapter Four. Thy-1-Interacting Molecules and Cellular Signaling in Cis and Trans

Abbreviations

1 Introduction

2 Thy-1 Molecule

3 Thy-1 Cis-Interacting Molecules and Signaling

4 Trans-Interacting Thy-1 Molecules and Signaling

5 Function of Thy-1 Molecule

6 Concluding Remarks

Acknowledgments

References

Chapter Five. Discovery of Survivin Inhibitors and Beyond: FL118 as a Proof of Concept

1 Introduction

2 Inhibitors That Disrupt Survivin Interactions with Other Proteins

3 Compounds That Inhibit Survivin Expression

4 Compounds with Controversial Effects on Survivin Expression

5 Survivin Inhibitors Discovered by HTS

6 Conclusion Remark

Acknowledgments

References

Chapter Six. New Insights into the Dynamics of Plant Cell Nuclei and Chromosomes

1 Introduction

2 Plant Nuclear Dynamics

3 Plant Chromosome Dynamics

4 Endoreduplication and Endomitosis

5 Concluding Remarks and Perspectives

Acknowledgments

References

Chapter Seven. Role of Cyclin B1 Levels in DNA Damage and DNA Damage-Induced Senescence

1 Introduction

2 Regulation of Cyclin B1

3 DNA-Damage Responses

4 DNA Damage-Induced Senescence

5 Cyclin B1 Levels as a Marker for Prognosis

6 Concluding Remarks

References

Chapter Eight. Transcription Factors in Alkaloid Biosynthesis

Abbreviations

1 Introduction

2 Transcription Factors in Alkaloid Biosynthesis

3 Upstream Signals: Jasmonate and Its Signaling Cascade

4 Evolution of Regulatory Mechanisms in Secondary Metabolism

5 Application of Transcription Factors to Natural Product Engineering

6 Conclusion

Acknowledgments

References

Chapter Nine. New Insights into the Transport Mechanisms in Plant Vacuoles

1 Introduction

2 Diversity of Mechanisms Involved in Vacuolar Transport

3 Classification of Transport Substances in Vacuolar Accumulation

4 Concluding Remarks and Future Perspectives

References

Index