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Innovation in Health Informatics

A Smart Healthcare Primer

  • 2nd Edition - June 12, 2026
  • Latest edition
  • Editors: Miltiadis Lytras, Akila Sarirete, Patricia Ordonez de Pablos
  • Language: English

Innovation in Health Informatics: Driving Value-Based Healthcare through Economic Efficiency, Second Edition addresses rapid advancements in health informatics by integr… Read more

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Description

Innovation in Health Informatics: Driving Value-Based Healthcare through Economic Efficiency, Second Edition addresses rapid advancements in health informatics by integrating the latest technologies and methodologies. The revised edition includes new chapters on Digital Twins, Blockchain, AI Applications for Personalized Medicine, and Health Analytics Dashboards, enriching foundational topics. The book delves into the economic implications and practical applications of these technologies, offering evidence-based strategies for their integration into healthcare systems. For the academic audience, this book bridges the gap between theory and practice, featuring practical case studies, end-of-chapter summaries, and interactive components like QR codes linking to online resources and simulation videos.

The primary goals of this revision are to update the book with the latest technological advancements, expand the scope to include emerging topics, and enhance existing chapters, ensuring it remains a comprehensive resource for professionals and students. This updated edition equips readers with up-to-date knowledge and tools to navigate and innovate within the evolving landscape of health informatics.

Key features

  • Includes new chapters on cutting-edge topics such as digital twins, blockchain, AI applications for personalized medicine, and health analytics dashboards
  • Provides actionable insights and real-world applications, making complex concepts accessible and practical for implementation through updated case studies, examples, and interactive components like QR codes
  • Equips readers with the knowledge and strategies needed to stay ahead in the rapidly evolving field of health informatics, ensuring relevance across various regions

Readership

Researchers, faculty, and students in the fields of health informatics, healthcare management, biomedical engineering, public health, medical informatics, and health policy

Table of contents

Section I: Smart healthcare in the era of big data and data science

1. Artificial intelligence-driven health informatics: Setting the new landscape for personalized and value-based healthcare
Miltiadis Lytras, Akila Sarirete, Patricia Ordonez De Pablos, Fotini Koutroumpa


2. Smart healthcare: Emerging technologies, best practices and sustainable policies
Miltiadis Lytras, Akila Sarirete, Paraskevi Papadopoulou


3. Syndromic surveillance using web data: A systematic review
Loukas Samaras, Elena García-Barriocanal, Miguel-Angel Sicilia


4. Digital twin technology: Foundations, applications and implications for next generation healthcare
Miltiadis Lytras, Dimitrios Lytras, Akila Sarirete


5. Natural language processing, sentiment analysis and clinical analytics: From traditional approaches to large language models
Adil Rajput

Section II: Advanced decision making and artificial intelligence for smart healthcare

6. Clinical decision support for infection control in surgical care
Marco Spruit, Sander Van Der Rijnst


7. Human activity recognition using artificial intelligence and machine learning in Internet of Things–enabled healthcare systems
Abdulhamit Subasi, Tayeb Brahimi, Akila Sarirete, Kholoud Khateeb


8. Application of machine learning and image processing for detection of breast cancer
Muhammad Kashif, Kaleem Razzaq Malik, Sohail Jabbar, Junaid Chaudhry


9. Preserving critical health information: Challenges and innovations in healthcare systems
Ramzi A. Haraty, Omar Zarif

Section III: Emerging technologies and systems for smart healthcare

10. The foundations of artificial intelligence: Towards new models of healthcare delivery and innovative services
Patricia Ordonez De Pablos, Miltiadis Lytras, Dimitrios Lytras


11. Security and privacy solutions for smart healthcare systems
Yang Lu, Richard O. Sinnott


12. Cloud-based health monitoring framework using smart sensors and smartphone
Abdulhamit Subasi, Lejla Bandic, Saeed Mian Qaisar


13. Artificial intelligence–assisted detection of diabetic retinopathy on digital fundus images: Concepts and applications in the National Health Service
Michael Kouroupis, Nikolaos Korfiatis, James Cornford


14. The next generation of medical applications based on virtual reality and sensors
Félix Mata, Miguel Torres-Ruiz, Roberto Zagal-Flores, Marco Moreno-Ibarra


15. A smart portable diagnostic solution for early-stage detection of diabetic retinopathy
Nighat Mir, Mohammad A.U. Khan, Mome Gul Hussain, Omar Alomeir


16. Improved nodule detection in chest X-rays using principal component analysis filters
Mohammad A.U. Khan, Nighat Mir, Omar Alomeir, Fahad Hameed Ahmad


17. The Internet of Medical Things and personal area networks: Standards, challenges, and applications in smart healthcare
Adil Rajput, Tayeb Brahimi

Section IV: Social issues and policy making for smart healthcare

18. Threats to patients’ privacy in smart healthcare environment: From traditional vulnerabilities to blockchain and quantum-era challenges
Samara M. Ahmed, Adil Rajput


19. Policy implications for smart healthcare: The international collaboration dimension
Miltiadis Lytras, Akila Sarirete, Vassilios Stasinopoulos


20. Health Informatics 2040: A robust and sustainable pathway to super intelligence
Miltiadis Lytras, Dimitrios Lytras, Patricia Ordonez De Pablos, Akila Sarirete

Product details

  • Edition: 2
  • Latest edition
  • Published: June 17, 2026
  • Language: English

About the editors

ML

Miltiadis Lytras

Miltiadis D. Lytras is a Professor of Artificial Intelligence, Digital Transformation, and Knowledge Management at Effat University (Saudi Arabia) and The American College of Greece. He is an internationally recognized researcher with extensive experience in AI, data science, smart systems, and digital innovation across healthcare, education, government, and business. He has served as Principal Investigator and Senior Researcher in numerous international and national research projects and has published more than 100 peer-reviewed articles and over 40 books with leading international publishers. His work focuses on responsible and human-centered AI, advanced decision-making systems, and the strategic impact of emerging technologies on organizations and society.
Affiliations and expertise
Professor, Effat University, College of Engineering, Saudi Arabia

AS

Akila Sarirete

Dr. Akila Sarirete is Dean of Graduate Studies and Research at Effat University. She received her PhD degree in Computer Science and Knowledge Management. Her main research interests are in artificial intelligence, knowledge management, communities of practice, machine learning, big data, and service-oriented architectures. She presented her research work in several conferences in different countries. Dr. Sarirete has a vast experience in software development industry and software engineering. She is interested in engineering education, innovation, smart cities and villages especially, the human aspect and the collaborative work.
Affiliations and expertise
Assistant Professor, Computer Science Department, College of Engineering, Deree College, The American College of Greece, Greece and Dean of Graduate Studies and Research, Effat University, Kingdom of Saudi Arabia

Pd

Patricia Ordonez de Pablos

Patricia de Pablos is a Professor of Business Administration at the University of Oviedo in Spain. Her field of research focuses on knowledge management, healthcare sector, innovation, information technologies and technological disruption. She has contributed to numerous academic publications. She has wide editorial experience in journals, books and book series. She serves as Editor in Chief of International Journal of Asian Business and Information and Journal of Science and Technology Policy Management.

Affiliations and expertise
Professor, Faculty of Economics and Business, The University of Oviedo,  Spain

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