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Inflammation and Natural Products

1st Edition - January 19, 2021

Editors: Sreeraj Gopi, Augustine Amalraj, Ajaikumar B. Kunnumakkara, Sabu Thomas

Paperback ISBN:

9 7 8 - 0 - 1 2 - 8 1 9 2 1 8 - 4

eBook ISBN:

9 7 8 - 0 - 1 2 - 8 1 9 2 1 9 - 1

Inflammation and Natural Products brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products,… Read more

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Inflammation and Natural Products brings together research in the area of the natural products and their anti-inflammatory action in medical, nutraceutical and food products, addressing specific chronic inflammatory diseases like cancer and the mechanistic aspects of the mode of action of some key natural products. Inflammation is a complicated process, driven by infection or injury or genetic changes, which results in triggering signalling cascades, activation of transcription factors, gene expression, increased levels of inflammatory enzymes, and release of various oxidants and pro-inflammatory molecules in inflammatory cells. Excessive oxidants and inflammatory mediators have a harmful effect on normal tissue, including toxicity, loss of barrier function, abnormal cell proliferation, inhibiting normal function of tissues and organs and finally leading to systemic disorders. The emerging development of natural product formulations utilizing the unique anti-inflammatory compounds such as polyphenols, polysaccharides, terpenes, fatty acids, proteins and several other bioactive components has shown notable successes. Inflammation and Natural Products: Recent Development and Current Status provides a comprehensive resource, ranging from detailed explanation on inflammation to molecular docking strategies for naturally occurring compounds with anti-inflammatory activity. It is useful for graduate students, academic and professionals in the fields of pharmaceutical and medical sciences and specialists from natural product-related industries.

Sreeraj Gopi

Dr. Sreeraj Gopi is Chief Scientist at Plant Lipids Pvt Ltd. and Chief Scientific Officer at Aurea Biolabs Pvt Ltd., and has also served as an adjunct professor at universities including Stockholm University, Sweden, Siberian Federal University, Russia, and Mahatma Gandhi University, India. He completed his doctorate in organic chemistry and nanotechnology, working in the area of natural products, isolation, and biological activities. He has published more than 75 international articles and filed more than 70 patents, including in the US and Europe. In his work at Plant Lipids, he has developed many innovative products and technologies, and is responsible for driving the research team to excellence, as well as the generation, implementation of new projects, and the presentation of scientific seminars to various customers.

Affiliations and expertise

Chief Scientist, Plantlipids Pvt Ltd and Chief Scientific Officer, Aurea Biolabs Pvt Ltd. Cochin, India

Augustine Amalraj

Dr. Augustine Amalraj is currently working as an Assistant Manager in the Department of Research and Development at Plant Lipids Private Limited, Cochin, India. He obtained his Doctoral degree in Chemistry from Gandhigram Rural Institute – Deemed University, Gandhigram, Tamil Nadu, India. His research interests are in applied chemistry, food chemistry, natural product chemistry, environmental chemistry, chemosensors, and polymer and nanocomposite materials. He has published more than 40 research articles in international journals, as well as 6 book chapters.

Affiliations and expertise

Aurea Biolabs Private Ltd, India

Ajaikumar B. Kunnumakkara

Prof. Ajaikumar Kunnumakkara, is a faculty member in the Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Assam, India. He is also an Honorary Chair Professor in Nanoscience and Nanotechnology. He is the principal investigator of Unit of Excellence in cancer drug discovery (DBT, Govt. of India) and the coordinator of DBT (India) - AIST (Japan) International Laboratory for Advanced Biomedicine. He earned his doctorate in 2006 from Amala Cancer Research Center, Thrissur, affiliated with University of Calicut, Kerala, India. Dr. Kunnumakkara did postdoctoral work at the University of Texas MD Anderson Cancer Center, Houston, Texas, USA (2005–2008) and the National Cancer Institute of National Institutes of Health (2008–2010) where he was subsequently employed as an NIH Scientist until 2012. Dr. Kunnumakkara has also edited four monographs. He is an elected Fellow of Royal Society of Medicine, UK as well as belonging to many other esteemed institutions.

Affiliations and expertise

Indian Institute of Technology Guwahati, India

Sabu Thomas

Professor Sabu Thomas is currently the Vice Chancellor of Mahatma Gandhi University and Director of the School of Energy Materials. He is also a full professor of Polymer Science and Engineering at the School of Chemical Sciences of Mahatma Gandhi University, Kottayam, Kerala, India, and the Founder Director and Professor of the International and Interuniversity Centre for Nanoscience and Nanotechnology. Prof. Thomas has received international acclaim for his work in Nanoscience, Polymer Science and Engineering, Polymer Nanocomposites, Elastomers, Polymer Blends, Interpenetrating Polymer Networks, Polymer Membranes, Green Composites and Nanocomposites, Nanomedicine and Green Nanotechnology.

Affiliations and expertise

Vice-chancellor, Mahatma Gandhi University, Kottayam, Kerala, India