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Immunomodulation in Domestic Food Animals
Advances in Veterinary Science and Comparative Medicine
- 1st Edition - November 28, 1990
- Editor: Bernald Charley
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 4 3 1 6 8 4 - 3
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 5 4 8 8 - 8
Immunomodulation in Domestic Food Animals covers the developments in the immunology and regulation of the immune response in domestic food animals. This book is organized into f… Read more
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Request a sales quoteImmunomodulation in Domestic Food Animals covers the developments in the immunology and regulation of the immune response in domestic food animals. This book is organized into four parts encompassing 12 chapters that describe numerous factors affecting an immune response of animals and the management of these factors for food animal production. Part I provides an overview of the basic concepts of immunomodulation and the rationale for manipulating the immune response in food animals. Part II contains information on immunopotentiation using chemicals and a thorough discussion of adjuvant use. The molecular biology and in vivo use of cytokines in food animals is presented in Part III. Lastly, Part IV discusses physiologically regulated immunomodulation, including nutritional modulation of the immune response and neuroendocrine-immune interactions. This book is of great value to immunologists, microbiologists, and feed scientists and researchers.
Contributors
Foreword
Preface
Part I: Introduction
Rationale for Using Immunopotentiators in Domestic Food Animals
I. Introduction
II. Why Are Immunomodulators Needed?
ΙII. Specific versus Nonspecific Immunomodulation
IV. Summary
References
Model Systems to Study Immunomodulation in Domestic Food Animals
I. Introduction
II. Stress Models
III. Glucocorticoid Immunosuppression Models
IV. Infectious Disease Model Systems
V. Summary
References
Mechanisms of Action of Some Immunomodulators Used in Veterinary Medicine
I. Introduction
II. Structure and Function of the Immune System
III. Immunomodulation
IV. Physiologically Important Immunomodulators
V. Synthetic Compounds with Immunomodulatory Activity
VI. Microbial Products as Immunomodulators
VII. Liposomes
VIII. Concluding Comments
References
Part II: Chemical Immunomodulation
Chemically Induced Immunomodulation in Domestic Food Animals
I. Introduction
II. Chemin Immunomodulation in Domestic Food Animal Species
ΙII. Chemical Immunomodulators Which Have Apparently Not Been Evaluated in Domestic Food Animals
IV. Summary
References
Classical and New Approaches to Adjuvant Use in Domestic Food Animals
I. Introduction
II. Aluminum Salts
ΙII. Oil Emulsions
IV. Surface Active Agents
V. ISCOMS
VI. Muramyldipeptides
VII. Polymeric Adjuvants
VIII. General Conclusions
References
A Thymosin-Tuftsin Conjugate as a New Potential Immunomodulator in Cattle
I. Introduction
II. Tuftsin: A Macrophage Activator
ΙII. Thymosin-α: A Τ Cell Activator
IV. Thymosin-Tuftsin Conjugate (IMP-1)
V. Conclusion
References
Part III: Cytokine Immunomodulation
The Molecular Biology of Large Animal Cytokines
I. Cytokine Biology
II. Recombinant Bovine and Porcine Cytokines
ΙII. Conclusions
References
Interferon Immunomodulation in Domestic Food Animals
I. Introduction
II. Modulation of Nonspecific Antimicrobial Defense Mechanisms
ΙII. Modulation of the Specific Cellular Immune Response
IV. Enhancement of Antimicrobial Mechanisms in the Gut
V. Immunoenhancement in Noninfectious Diseases
VI. Concluding Remarks
References
In Vivo Use of Interleukins in Domestic Food Animals
I. Introduction
II. Rationale for Using Interleukins in Domestic Food Animals
ΙII. In Vivo Studies with Interleukins in Domestic Food Animals
IV. Conclusions and Prospects
References
Part IV: Physiologically Regulated Immunomodulation
Nutritional Modulation of Immunity in Domestic Food Animals
I. Introduction
II. Protein and Energy
ΙII. Fat-Soluble Vitamins
IV. Water-Soluble Vitamins
V. Minerals
VI. Conclusion
References
Neuroendocrine-Immune Interactions
I. Introduction
II. Characteristics of the Neuroendocrine-Immune System
ΙII. Conclusions
References
Potential for Improving Animal Health by Modulation of Behavior and Immune Function
I. Introduction
II. Behavior of Farm Animals
ΙII. Social Behavior and Immune Function
IV. Nonsocial Behaviors and Immune Function
V. Brain-Immune Interactions
VI. Concluding Remarks
References
Index
- No. of pages: 348
- Language: English
- Edition: 1
- Published: November 28, 1990
- Imprint: Academic Press
- Paperback ISBN: 9780124316843
- eBook ISBN: 9780323154888