Immunity, Cancer, and Chemotherapy
Basic Relationship on the Cellular Level
- 1st Edition - January 1, 1967
- Editor: Enrico Mihich
- Language: English
- Paperback ISBN:9 7 8 - 1 - 4 8 3 2 - 5 0 8 7 - 8
- Hardback ISBN:9 7 8 - 1 - 4 8 3 2 - 2 7 6 2 - 7
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 5 9 0 0 - 0
Immunity, Cancer, and Chemotherapy focuses on the interference of drugs on antibody response and transplantation immunity. The selection first offers information on the effects… Read more

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Request a sales quoteImmunity, Cancer, and Chemotherapy focuses on the interference of drugs on antibody response and transplantation immunity. The selection first offers information on the effects of immunosuppressive drugs on cellular changes after antigenic stimulation and specialized cell function in the lymphoid and reticuloendothelial cell series. Topics include effects of immunosuppressive drugs on the sensitization process; cellular changes in lymphoid tissue following sensitization; and demonstration of differences in antigen handling among cells of the reticuloendothelial system. The text also takes a look at allogeneic inhibition and its possible relation to cell-bound immunity in vitro and the effects of immunosuppressive drugs at various stages of differentiation of immunologically competent cells. The publication examines a study of antibody-containing cells in the course of immunization and cellular differentiation during immune responses studied with electron microscope and radioautography. The text also elaborates on ambiguity in the translation of genetic code into proteins, induced by aminoglycoside antibiotics and immunosuppressive agents and cellular kinetics of immune response. The selection is a dependable source of information for readers interested in effects of drugs on antibody response and transplantation immunity.
articipants
List of Contributors
Foreword
Preface
The Effect Of Immunosuppressive Drugs On Cellular Changes After Antigenic Stimulation
I. Cellular Changes In Lymphoid Tissue Following Sensitization
II. Effect of Immunosuppressive Drugs on the Sensitization Process
III. Conclusions
References
Discussion
Specialized Cell Function In The Lymphoid And Reticuloendothelial Cell Series
I. Demonstration of Differences In Antigen Handling Among Cells of the Reticuloendothelial System
II. Specialization of Cells of the Lymphoid System
III. Concluding Remarks
References
Discussion
Allogeneic Inhibition And Its Possible Relation To Cell-Bound Immunity In Vitro
I. Attempts to Demonstrate Allogenic Inhibition in Vitro
II. Summary
Acknowledgments
References
Discussion
The Effect Of Immunosuppressive Drugs At Various Stages Of Differentiation Of Immunologically Competent Cells
I. Definition Of The Inductive Phase By The Use Of Metabolic Inhibitors
II. The Influence Of Metabolic Inhibitors On Antibody Production
III. The Influence Of Inhibitors On The Preparation For The Secondary Response
IV. The Influence Of Inhibitors On The Secondary Response
V. Studies On Immunological Inhibition (Tolerance) Using Metabolic Inhibitors
VI. Unitarian Concept Of Immune Reactions Based On The Model Of Immunological Cell Differentiation
References
Discussion
A Study Of Antibody-Containing Cells In The Course Of Immunization
I. Comparison Between The Results Obtained With The ICA And The Hemolysis Plaque Formation Techniques
II. Application Of The ICA Method To The Study Of Cells Producing Antibodies Against Haptens
III. Inhibition Of ICA By Heterologous Antibodies Against Immunoglobulins
IV. Kinetics Of The Appearance Of "Rosette"-Forming Cells In The Spleen Of Mice Immunized Intravenously With Sheep Erythrocytes
References
Discussion
Cellular Differentiation During Immune Responses Studied With The Electron Microscope And Radioautography
Text
References
Discussion
Concerning The Recognition Reaction And Transfer RNA In Protein Synthesis
Text
References
Discussion
Ambiguity In The Translation Of The Genetic Code Into Proteins, Induced By Aminoglycoside Antibiotics
Text
References
Discussion
Macrophage RNA And Antibody Synthesis
Text
References
Discussion
The Role Of Antigen In The Regulation Of Antibody Formation
I. Kinetics Of Antibody Formation To Bacteriophage φX 174 In Guinea Pigs
II. Immune Functions of Individual Antibody-Forming Cells
References
Discussion
Alteration Of Immunity By Antimetabolites
Text
References
Discussion
Immunosuppressive Agents And The Cellular Kinetics Of The Immune Response
I. Introduction
II. Materials And Methods
III. Results
IV. Discussion
V. Summary
References
Discussion
Immunochemical Studies Of Mammalian Cell Membranes
I. Introduction
II. The Immunochemical Problem
III. Methods For The Preparation Of Plasma Membranes
IV. Recognition Marker For Plasma Membrane
V. Composition Of Plasma Membrane Preparations
VI. General Discussion
References
Discussion
Tumor Antigens
Text
References
Discussion
Expression Of Antigens In Normal Mammalian Cells
I. Introduction
II. Cellular Antigens In Tissue Culture
III. Embryonic Differentiation Of Antigens
IV. Induction Of Antigens In The Thymus
V. Modification Of The Expression Of Normal Tissue Antigens In Vivo
VI. Differentiation Of Immunoglobulin-Producing Cells
VII. Closing Comments
References
Discussion
Mechanism Of Complement Action And Means Of Complement Depletion
I. Physiogenic And Pathogenic Role Of Complement
II. Mechanism Of Action Of Human Complement
III. Enhancement Of Complement
IV. Inhibition Of Complement
V. Inactivation Of C'3 By Cobra Factor
References
Discussion
Immunogenicity Of Synthetic Polymers Of Amino Acids; Role Of Carrier And Genetic Background
I. Introduction
II. Immunogenicity Of Linear Polymers Of α-L- And α-D-Amino Acids
III. Role Of Carrier In Influencing The Immune Response
IV. Genetic Control Of Immune Response
References
Discussion
Studies On Transplantation
I. Past Efforts
II. Causes Of Failure
III. Histocompatibility Matching
IV. Improved Immunosuppression
V. Other Organs
References
Discussion
Author Index
Subject Index
- No. of pages: 414
- Language: English
- Edition: 1
- Published: January 1, 1967
- Imprint: Academic Press
- Paperback ISBN: 9781483250878
- Hardback ISBN: 9781483227627
- eBook ISBN: 9781483259000
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