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Elsevier

Immune Landscape of Pancreatic Cancer Development and Drug Resistance

  • 1st Edition, Volume 5 - June 7, 2024
  • Latest edition
  • Editors: Batoul Farran, Ganji Purnachandra Nagaraju
  • Language: English

Immune Landscape of Pancreatic Cancer Development and Drug Resistance explores advances in immune-based therapies aimed at harnessing the power of the immune system against p… Read more

Description

Immune Landscape of Pancreatic Cancer Development and Drug Resistance explores advances in immune-based therapies aimed at harnessing the power of the immune system against pancreatic cancer and rewiring tumor microenvironments to eradicate pancreatic cells. With a strong focus on the development of therapeutic methods to improve the survival rates of pancreatic cancer, this book also shows the latest trends in immune targeted approaches for pancreatic cancer treatment. In 12 chapters, the book discusses our current understanding of PC development and its various mutational and immune features and explore some of the new immune-based therapies aimed at targeting pancreatic cancer.

This book is a valuable resource for health professionals, scientists and researchers, students, and all those who wish to broaden their knowledge of advances in immunotherapy in pancreatic cancer.

Key features

  • Summarizes the potential combination strategies and latest clinical trials in pancreatic cancer
  • Provides an in-depth overview of our current understanding of pancreatic cancer development, including its mutational and immune features
  • Explores some of the new immune-based therapies aimed at targeting PC
  • Shows pancreatic cancer progression and basic elements in tumor microenvironments and their role in PC progression, also covering immunotherapy strategies

Readership

Graduate students and researchers in cancer research Oncologists, clinicians

Table of contents

1. Introduction

2. Molecular profiling and mutational landscape of pancreatic cancer

3. Tumor microenvironment and immune components interaction in pancreatic ductal adenocarcinoma

4. Identification of immune targeted molecules in pancreatic ductal adenocarcinoma

5. Targeting macrophages for pancreatic cancer therapy

6. Targeting cancer-associated fibroblasts in pancreatic ductal adenocarcinoma

7. Targeting short-lived immunosuppressive myeloid cells for PDAC therapy

8. Targeting T-regs in PDAC

9. Immune-modulators for PDAC therapy

10. Current clinical trials in PDAC immunotherapy

11. Precision medicine in PDAC immunotherapy

12. Artificial intelligence in pancreatic cancer immunotherapy

Product details

  • Edition: 1
  • Latest edition
  • Volume: 5
  • Published: June 14, 2024
  • Language: English

About the editors

BF

Batoul Farran

Batoul Farran is an associate scientist in the Department of Oncology at the Albert Einstein College of Medicine, USA. She obtained her PhD in Structural and Molecular Biology from University College London, UK. She completed her postdoctoral fellowship at the Department of Hematology and Medical Oncology at the Winship Cancer Institute, Emory University School of Medicine, USA. Her work focuses on translational cancer research, specifically on targeted and immune therapies in colorectal, pancreatic and lung cancers. She has authored several publications in highly reputed international journals.
Affiliations and expertise
Associate scientist,Department of Oncology, Albert Einstein College of Medicine, Bronx, USA

GN

Ganji Purnachandra Nagaraju

Dr. Nagaraju obtained his MSc and his PhD, both in Biotechnology, from Sri Venkateswara University in Tirupati, Andhra Pradesh, India. He received his DSc from Berhampur University in Berhampur, Odisha, India. Dr. Nagaraju’s research focuses on translational projects related to gastrointestinal malignancies. He has published over 100 research papers in highly reputed international journals and has presented more than 50 abstracts at various national and international conferences. Dr. Nagaraju is author and editor of several published books for Elsevier and Springer Nature. He serves as editorial board member of several internationally recognized academic journals. Dr. Nagaraju has received several international awards including FAACC. He also holds memberships with the Association of Scientists of Indian Origin in America (ASIOA), the Society for Integrative and Comparative Biology (SICB), The Science Advisory Board, The RNA Society, The American Association for Clinical Chemistry (AACC) and the American Association of Cancer Research (AACR).
Affiliations and expertise
Assistant Professor, School of Medicine, Division of Hematology and Oncology, University of Alabama, Birmingham, AL, USA

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