Human Molecular Genetics
- 1st Edition, Volume 8 - May 23, 1996
- Latest edition
- Editor: Kenneth W. Adolph
- Language: English
Human Molecular Genetics is a practical guide to the applications of molecular biology and genetics techniques to human cells. A wide range of experimental procedures for… Read more
Human Molecular Genetics is a practical guide to the applications of molecular biology and genetics techniques to human cells. A wide range of experimental procedures for investigating human genes and genomes are presented.
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* Mutation Detection in Human Genes - chemical mismatch cleavage, DNA mini-sequencing, SSCP method, RT-PCR, electrophoretic mobility shift assay (EMSA), protein truncation test, chromosome deletion analysis.
* Gene Mapping, Cloning, Sequencing - gene linkage determination, large-capacity cloning system, cDNA isolation, differential display method, primer-based DNA sequencing.
* Transcription: Promoters, Transcription Factors, mRNA, - promotor mutation analysis, transcription factor identification, mRNA-protein interaction characterization.
* RNA Editing, Ribozymes, Antisense RNA-mammalian RNA editing assays, ribozymes as genetic tools, antisense RNA technology.
* Genome Recombination, Amplification - recombination assays for mammalian cells, gene amplification measurement.
* Receptors, Signal Transduction - intra-cellular receptor characterization, analysis of signal transduction genes.
* The Mouse as a Model System for Human Molecular Genetics - mouse genome methods (mouse crosses, somatic cell hybrids, YACs), mouse model for cardiovascular disease.
* Mutation Detection in Human Genes - chemical mismatch cleavage, DNA mini-sequencing, SSCP method, RT-PCR, electrophoretic mobility shift assay (EMSA), protein truncation test, chromosome deletion analysis.
* Gene Mapping, Cloning, Sequencing - gene linkage determination, large-capacity cloning system, cDNA isolation, differential display method, primer-based DNA sequencing.
* Transcription: Promoters, Transcription Factors, mRNA, - promotor mutation analysis, transcription factor identification, mRNA-protein interaction characterization.
* RNA Editing, Ribozymes, Antisense RNA-mammalian RNA editing assays, ribozymes as genetic tools, antisense RNA technology.
* Genome Recombination, Amplification - recombination assays for mammalian cells, gene amplification measurement.
* Receptors, Signal Transduction - intra-cellular receptor characterization, analysis of signal transduction genes.
* The Mouse as a Model System for Human Molecular Genetics - mouse genome methods (mouse crosses, somatic cell hybrids, YACs), mouse model for cardiovascular disease.
Mutation Detection in Human Genes. Gene Mapping, Cloning, Sequencing. Transcription: Promoters, Transcription Factors, Mrna. RNA Editing, Ribozymes, Antisense RNA. Genome Recombination Amplification. Receptors, Signal Transduction. The Mouse as a Model System for Human Molecular Genetics.
- Edition: 1
- Latest edition
- Volume: 8
- Published: May 23, 1996
- Language: English
KA
Kenneth W. Adolph
Affiliations and expertise
University of Minnesota Medical School, Minneapolis, Minnesota, USARead Human Molecular Genetics on ScienceDirect