Human Genetics, 6e
- 6th Edition - April 14, 2021
- Imprint: Elsevier India
- Author: S D Gangane
- Language: English
- Paperback ISBN:9 7 8 - 8 1 - 3 1 2 - 6 2 0 9 - 2
- eBook ISBN:9 7 8 - 8 1 - 3 1 2 - 6 2 1 0 - 8
The sixth edition of this book is revised as per guidelines of National Medical Commission in accordance with the competency-based curriculum of Genetics. This book forms a con… Read more
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The sixth edition of this book is revised as per guidelines of National Medical Commission in accordance with the competency-based curriculum of Genetics. This book forms a concise version chiefly designed to cater to the needs of undergraduate students. The aim has been to offer the basic principles without superfluous details.
• Text is presented in a simple and precise manner, with complex information summarized in tables and line diagrams, which makes the learning easier for students.
• Presentation is visually more appealing with the insertion of clinical pictures along with the text.
• Recapitulation of summary at the end of chapters would also help students to quickly review and revise the subject before examination.
• Questions given at the end of each chapter along with answers for self-assessment of the topics studied.
• Prepares students for both theory and viva voce.
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Preface to the sixth edition
- Preface to the first edition
- Acknowledgements
- Competency map
- List of Tables
- List of Illustrations
- 1. Historical gleanings
- Mendel and mendelism
- Milestones in the development of genetics
- 2. Cytogenetics
- Mitosis
- Meiosis
- Gametogenesis
- Fertilisation
- Human chromosomes AN 73.1
- Sex chromatin
- 3. Molecular genetics
- Structure of nucleic acid
- Transcription and translation
- Gene
- Mutation AN 75.4
- Polymerase chain reaction
- Southern blot technique
- Northern blotting
- DNA fingerprinting technology
- DNA sequencing
- Microarray technology
- CRISPR-cas9
- Human genome project
- 4. Chromosomal aberrations
- Structural aberrations AN 75.1
- Autosomal abnormalities AN 75.1
- Sex chromosome abnormalities AN 75.1
- Sex development errors with normal chromosomes
- Chimaeras AN 75.2
- 5. Developmental genetics
- Fertilisation
- Factors influencing development
- Genes involved in development
- Multiple malformation syndromes
- Sex determination and differentiation
- Inactivation of X chromosome
- 6. Modes of inheritance
- Analysis of genetic disorders
- Mendelian inheritance (single gene disorders) AN 74.1
- 7. Biochemical genetics
- Inborn errors of metabolism
- Haemoglobins and haemoglobinopathies
- Pharmacogenetics and disorders related to drugs
- 8. Genetics of blood groups
- Clinical applications
- ABO blood group system
- Rhesus blood group system
- Other blood group systems
- Other polymorphisms in blood AN 75.4
- 9. Immunogenetics
- Immunoglobulins
- Hybridoma and monoclonal antibodies
- Transplantation
- Human leucocyte antigen (HLA) system
- Immune system disorders
- 10. Cancer genetics
- Retrovirus
- Oncogenes
- Chromosomal aberrations in cancer
- 11. Genetic component in common diseases
- Genetic susceptibility
- Demonstration of genetic susceptibility
- Hypertension
- Peptic ulcer
- Alzheimer disease
- 12. Population genetics
- Hardy–weinberg’s law
- Beanbag genetics
- Calculating gene frequency
- Eugenics
- Twins AN 80.4
- Abnormal twinning AN 80.4
- Cloning AN 80.4
- Dermatoglyphics
- 13. Prenatal diagnosis
- Amniocentesis AN 81.1, 81.2
- Chorion villous biopsy AN 81.1, 81.3
- Ultrasonography AN 81.1
- Foetoscopy AN 81.1
- Foetal blood sampling (FBS) AN 81.1
- Maternal serum sample AN 81.1
- Preimplantation diagnosis AN 81.1
- Recombinant DNA
- 14. Genetic counselling
- History AN 75.5
- Pedigree charting AN 75.5
- Estimation of risk AN 75.5
- Transmitting information AN 75.5
- Management AN 75.5
- Preventive aspects AN 75.5
- Follow-up in genetic clinics AN 75.5
- Genetic screening AN 75.5
- Screening programmes AN 75.5
- Legal implications AN 75.5
- 15. Gene therapy
- Governing bodies
- Gene delivery
- Gene transfer techniques
- Diseases amenable to gene therapy
- Future prospects
- 16. Stem cell therapy
- Stem cell
- Stem cell therapies today
- Synthetic cornea
- Ethical, legal and social issues
- Recent pandemic of COVID-19
- Future
- 17. Epigenetics
- Definition
- Effects of epigenetics on development
- Glossary
- Answers
- Bibliography
- Index
- Edition: 6
- Published: April 14, 2021
- Imprint: Elsevier India
- Language: English
- Paperback ISBN: 9788131262092
- eBook ISBN: 9788131262108