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Hematology and Coagulation
A Comprehensive Review for Board Preparation, Certification and Clinical Practice
- 1st Edition - January 21, 2015
- Authors: Amer Wahed, Amitava Dasgupta
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 0 0 2 4 1 - 4
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 0 0 3 8 1 - 7
Hematology and Coagulation is a clear and easy-to-read presentation of core topics and detailed case studies that illustrate the application of hematopathology knowledge to everyd… Read more
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Request a sales quoteHematology and Coagulation is a clear and easy-to-read presentation of core topics and detailed case studies that illustrate the application of hematopathology knowledge to everyday patient care. In order to be successful, as well as to pass the American Board of Pathology examination, all pathology residents must have a good command of hematopathology, including the challenging topics of hematology and coagulation. Hematology and Coagulation meets this challenge head on.
This basic primer offers practical examples of how things function in the hematopathology clinic as well as useful lists, sample questions, and a bullet-point format ideal for quick pre-board review. This book provides only the most clinically relevant examples designed to educate senior medical students, residents and fellows and "refresh" the knowledge base, without overwhelming students, residents, and clinicians.
- Takes a practical and easy-to-read approach to understanding hematology and coagulation at an appropriate level for both board preparation as well as a professional refresher course
- Covers all important clinical information found in larger textbooks in a more succinct and easy-to-understand manner
- Covers essential concepts in hematopathology in such a way that fellows and clinicians understand the methods without having to become specialists in the field
Residents and fellows in pathology and clinical chemistry, practicing pathologists and clinical chemists
- Dedication
- Preface
- Chapter 1. Complete Blood Count and Peripheral Smear Examination
- 1.1 Introduction
- 1.2 Analysis of Various Parameters by Hematology Analyzers
- 1.3 Review of Peripheral Smear
- 1.4 Special Situations with CBC and Peripheral Smear Examination
- Key Points
- References
- Chapter 2. Bone Marrow Examination and Interpretation
- 2.1 Introduction
- 2.2 Fundamentals of Bone Marrow Examination
- 2.3 Bone Marrow Examination Findings and Bone Marrow Failure
- Key Points
- References
- Chapter 3. Red Blood Cell Disorders
- 3.1 Introduction
- 3.2 Anemia: Morphological and Etiological Classification
- 3.3 Common Causes of Anemia
- 3.4 Hemolytic Anemia
- 3.5 Red Cell Poikilocytosis
- 3.6 Red Cell Inclusions
- Key Points
- References
- Chapter 4. Hemoglobinopathies and Thalassemias
- 4.1 Introduction
- 4.2 Hemoglobin Structure and Synthesis
- 4.3 Introduction to Hemoglobinopathies
- 4.4 Other Hemoglobin Variants
- 4.5 Laboratory Investigation of Hemoglobinopathies
- 4.6 Diagnostic Tips for Thalassemias, Sickle Cell Disease, and Other Hemoglobinopathy
- 4.7 Apparent Hemoglobinopathy After Blood Transfusion
- Key Points
- References
- Chapter 5. Benign White Blood Cell and Platelet Disorders
- 5.1 Introduction
- 5.2 Hereditary Variation in White Blood Cell Morphology
- 5.3 Changes in White Cell Counts
- 5.4 Platelet Disorders
- Key Points
- References
- Chapter 6. Myeloid Neoplasms
- 6.1 Introduction
- 6.2 Classification of Myeloid Neoplasm
- 6.3 Myeloproliferative Neoplasm
- 6.4 Myeloid and Lymphoid Neoplasm Associated with Eosinophilia
- 6.5 Myelodysplastic/Myeloproliferative Neoplasms
- 6.6 Myelodysplastic Syndrome
- 6.7 Acute Leukemia
- Key Points
- References
- Chapter 7. Monoclonal Gammopathy and Its Detection
- 7.1 Introduction
- 7.2 Diagnostic Approach to Monoclonal Gammopathy Using Electrophoresis
- 7.3 Plasma Cell Neoplasm
- 7.4 Cytogenetics in Myeloma Diagnosis
- Key Points
- References
- Chapter 8. Application of Flow Cytometry in the Diagnosis of Hematological Disorders
- 8.1 Introduction
- 8.2 Flow Cytometry and Mature B Cell Lymphoid Neoplasms
- 8.3 Flow Cytometry and Mature T and Natural Killer Cell Lymphoid Neoplasms
- 8.4 Plasma Cell Dyscrasias
- 8.5 Flow Cytometry and Acute Leukemia
- 8.6 Flow Cytometry and Myelodysplastic Syndrome
- 8.7 Flow Cytometry and Hematogones
- Key Points
- References
- Chapter 9. Cytogenetic Abnormalities and Hematologic Neoplasms
- 9.1 Introduction
- 9.2 Cytogenetic Abnormalities in Chronic Myeloid Leukemia
- 9.3 Cytogenetic Abnormalities in Myelodysplastic Syndrome
- 9.4 Cytogenetic Abnormalities in Patients with Acute Myeloid Leukemia
- 9.5 Cytogenetic Abnormalities in Actute Lymphoblastic Leukemia
- 9.6 Cytogenetic Abnormalities in Multiple Myeloma
- 9.7 Cytogenetic Abnormalities in B and T Cell Lymphomas
- Key Points
- References
- Chapter 10. Benign Lymph Nodes
- 10.1 Introduction
- 10.2 Reactive Lymphoid States
- 10.3 Specific Clinical Entities with Lymphadenopathy
- Key Points
- References
- Chapter 11. B Cell Lymphomas
- 11.1 Introduction
- 11.2 Follicular Lymphoma
- 11.3 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
- 11.4 B Cell Prolymphocytic Leukemia
- 11.5 Mantle Cell Lymphoma
- 11.6 Marginal Zone B Cell Lymphoma
- 11.7 Burkitt Lymphoma
- 11.8 Lymphoblastic Leukemia/Lymphoblastic Lymphoma
- 11.9 Lymphoplasmacytic Lymphoma/Waldenström Macroglobulinemia
- 11.10 Diffuse Large B Cell Lymphoma
- 11.11 Hairy Cell Leukemia
- Key Points
- References
- Chapter 12. T Cell and Natural Killer Cell Lymphomas
- 12.1 Introduction
- 12.2 Nodal T Cell Lymphomas
- 12.3 Extranodal NK/T Cell Lymphomas
- 12.4 Cutaneous T Cell Lymphoma
- 12.5 Leukemia/disseminated
- Key Points
- References
- Chapter 13. Hodgkin Lymphoma
- 13.1 Introduction
- 13.2 Overview of Hodgkin Lymphoma
- 13.3 Classification of Hodgkin Lymphoma
- 13.4 Immunostains for Diagnosis of Hodgkin Lymphoma
- 13.5 Staging of Hodgkin Lymphoma
- Key Points
- References
- Chapter 14. Lymphoproliferative Disorders Associated with Immune Deficiencies and Histiocytic and Dendritic Cell Neoplasms
- 14.1 Introduction
- 14.2 Lymphoproliferative Disorders Associated with Immune Deficiency
- 14.3 Histiocytic and Dendritic Cell Neoplasms
- Key Points
- References
- Chapter 15. Essentials of Coagulation
- 15.1 Introduction
- 15.2 Normal Hemostasis
- 15.3 Thrombocytopenia and Thrombocytopathia
- 15.4 Tests for Platelet Function
- 15.5 Secondary Hemostasis
- 15.6 Tests for Secondary Hemostasis
- 15.7 Antiplatelets and Anticoagulants
- Key Points
- References
- Chapter 16. Thrombophilias and Their Detection
- 16.1 Introduction
- 16.2 Thrombophilia: Inherited Versus Acquired
- 16.3 Factor V Leiden
- 16.4 Prothrombin Gene Mutation
- 16.5 Protein C Deficiency
- 16.6 Protein S Deficiency
- 16.7 Antithrombin III Deficiency
- 16.8 Hyperhomocysteinemia
- 16.9 Increased Factor VIII Activity
- 16.10 Acquired Causes of Thrombophilia
- Key Points
- References
- Chapter 17. Sources of Errors in Hematology and Coagulation
- 17.1 Introduction
- 17.2 Errors in Routine Hematology Testing
- 17.3 Errors in Specific Hematology Testing
- 17.4 Errors in Coagulation Testing
- Key Points
- References
- Index
- No. of pages: 324
- Language: English
- Edition: 1
- Published: January 21, 2015
- Imprint: Elsevier
- Hardback ISBN: 9780128002414
- eBook ISBN: 9780128003817
AW
Amer Wahed
Amer Wahed is a graduate of Medicine, training initially in Internal Medicine at Royal Postgraduate Medical School, London, England. He subsequently trained in Anatomic and Clinical Pathology from the University of Texas-Houston Medical School. After working for several years in a private setting, he joined the Department of Pathology and Laboratory Medicine at the University of Texas-Houston Health Sciences Center. Currently he is an Assistant Professor of Pathology and Laboratory Medicine and Associate Director of Clinical Chemistry and Immunology at Memorial-Hermann Hospital at the Texas Medical Center. He is also the Associate Director of the Pathology Residency Program at the University of Texas-Houston Medical School. Dr. Wahed has a strong interest in teaching and is actively involved in the education of medical students, graduate students, residents, and fellows. He has been recognized for his teaching contributions through awards from his department, as well as the Office of the Dean. He is also active in mentoring pathology residents in research and has published multiple papers in peer-reviewed journals.
Affiliations and expertise
Associate Professor of Pathology and Laboratory Medicine, University of Texas, McGovern School of Medicine, Houston, TX, USAAD
Amitava Dasgupta
Amitava Dasgupta received his Ph. D in chemistry from Stanford University and completed his fellowship training in Clinical Chemistry from the Department of Laboratory Medicine at the University of Washington School of Medicine at Seattle. He is board certified in both Toxicology and Clinical Chemistry by the American Board of Clinical Chemistry. Currently, he is a tenured Full Professor of Pathology and Laboratory Medicine at the University of Kansas Medical Center and Director of Clinical Laboratories at the University of Kansas Hospital. Prior to this appointment he was a tenured Professor of Pathology and Laboratory Medicine at the University of Texas McGovern medical School from February 1998 to April 2022. He has 252 papers to his credit. He is in the editorial board of four journals including Therapeutic Drug Monitoring, Clinica Chimica Acta, Archives of Pathology and Laboratory Medicine, and Journal of Clinical Laboratory Analysis.
Affiliations and expertise
Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS, United States