Handbook of Translational Transcriptomics
Research, Protocols and Applications
- 1st Edition - April 22, 2025
- Editor: Anton Buzdin
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 9 1 1 0 - 7
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 3 7 6 8 - 3
Handbook of Translational Transcriptomics: Research, Protocols and Applications provides a comprehensive overview on the field of transcriptomics. The book begins with an overview… Read more
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Request a sales quoteHandbook of Translational Transcriptomics: Research, Protocols and Applications provides a comprehensive overview on the field of transcriptomics. The book begins with an overview of the past, present, and potential approaches in the field of transcriptomics, with discussions on choosing the correct approach based on the research needed. The book also highlights the pros and cons of each approach and explores techniques and protocols for investigating specific avenues, focusing on RNA sequencing, expression arrays, and gene expression. Sections on data analysis offer recommendations, guidelines, and approaches related to data interpretation.
The book also considers the translation of transcriptomics to clinical application and applications in molecular diagnostics, biomarkers in medicine, and personalized medicine specific to oncology, as well as biotechnology for pharmaceutical research.
- Features practical guidance and protocols for researchers to replicate transcriptomic methods and techniques, including wet lab techniques
- Includes useful information on analyzing and interpreting transcriptomic data
- Offers a detailed introduction into translational transcriptomics, exploring both coding and non-coding RNAs, including microRNA
- Investigates clinical implications of transcriptomics and applications for treating disease
- Considers experimental and bioinformatic techniques in the field of transcriptomics, as well as more established approaches
1. Past, current and future of transcriptomics
2. Pitfalls of transcriptomics, and selection of the most appropriate transcriptomic technique
3. RNA sequencing in wet lab
4. Expression arrays in wet lab
5. High-throughput and multiplex PCR in wet lab to measure gene expression
6. Processing primary gene expression data: normalization, harmonization and data QC
7. Data check and comparison with the expression databases
8. Finding differentially expressed genes and gene sets
9. Molecular pathway analysis using transcriptomic data
10. OMICSwise analysis of RNA splicing
11. Transcriptomic biomarkers in medicine
12. Translational transcriptomics for personalized oncology
13. Transcriptomics for modern biotechnology
14. Transcriptomics and quantitative proteomics: competition or symbiosis?
- No. of pages: 390
- Language: English
- Edition: 1
- Published: April 22, 2025
- Imprint: Academic Press
- Paperback ISBN: 9780443191107
- eBook ISBN: 9780443237683
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