Handbook of Proteolytic Enzymes
Volume 4: Aspartic and Glutamic Peptidases, Asparagine Peptide Lyases and Peptidases of Unknown Catalytic Mechanisms
- 4th Edition - September 1, 2026
- Latest edition
- Editor: Neil D. Rawlings
- Language: English
The Handbook of Proteolytic Enzymes stands as the most comprehensive work in the field of applied enzymology and biocatalysis since the first edition published in 1998. Extensive… Read more
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The Handbook of Proteolytic Enzymes stands as the most comprehensive work in the field of applied enzymology and biocatalysis since the first edition published in 1998. Extensively revised and updated, the new, fourth edition is an essential reference for biochemists, biotechnologists, and molecular biologists across academia and industry. Edited by world-renowned experts in the field and with five volumes available for individual sale, this work provides detailed information on all known proteolytic enzymes researched to-date, with expanded coverage of metallopeptidases, cysteine peptidases, serine and threonine peptidases, aspartic and glutamic peptidases, and inhibitors of proteolytic enzymes.
This volume includes over 250 chapters on known aspartic and glutamic peptidases, asparagine peptide lysases, and peptidases of unknown catalytic mechanisms. Chapters discuss each enzyme’s name, history, activity and specificity, structural chemistry, preparation, biological aspects, and distinguishing features, with 2D and 3D structures of peptidases in color, extensive references, and links to PubMed and MEROPS databases.
- The only comprehensive book on aspartic and glutamic peptidases, asparagine peptide lysases, and peptidases of unknown catalytic mechanisms
- Each chapter written by experts in their field, on proteolytic enzymes from all groups of living organisms and viruses, including those that are currently major targets of pharmaceutical research
- Fully searchable text, 2D and 3D structures of peptidases in color, and links directly to PubMed and MEROPS databases
- Details the latest proteotases used in therapeutic research, and discusses recent drug trials
Active researchers in biochemistry, medical chemistry, organic chemistry, molecular biology, cell biology, pharmacology; clinician scientists; researchers in industry and pharma
I. New Chapters
1. Candidapepsin SAP2
2. Signal Peptide Peptidase-Like Protein 2A
II. Major Revisions
3. Pepsin A
4. Chymosin
5. Renin
6. Cathepsin D
7. Cathepsin E
8. Phytepsin
9. Plasmepsin-2
10. BACE1 g.p. (Homo sapiens)
11. BACE2 g.p. (Homo sapiens)
12. HIV-1 Retropepsin
13. Presenilin 1
- Edition: 4
- Latest edition
- Published: September 1, 2026
- Language: English
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