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Genitourinary Pathology, An Issue of Surgical Pathology Clinics
- 1st Edition, Volume 15-4 - November 9, 2022
- Editor: Ming Zhou
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 1 9 7 5 - 3
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 1 9 7 6 - 0
In this issue of Surgical Pathology Clinics, guest editor Dr. Ming Zhou brings his considerable expertise to the topic of Genitourinary Pathology. Top experts in the field cover… Read more
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Request a sales quoteIn this issue of Surgical Pathology Clinics, guest editor Dr. Ming Zhou brings his considerable expertise to the topic of Genitourinary Pathology. Top experts in the field cover key topics such as prostate cancer: update on grading and reporting; cribriform lesions of the prostate; urothelial carcinoma: divergent differentiation and variants; kidney tumors: new developments in existing WHO kidney tumor entities; and more.
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Contains 13 relevant, practice-oriented topics including testicular tumors: new developments in germ cell tumors and sex cord stromal tumors; computational pathology in genitourinary pathology; molecular genetics of prostate cancer and role of genomic testing; evolving role of multiparametric MRI in prostate cancer diagnosis and reporting; and more.
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Provides in-depth clinical reviews on current topics in genitourinary pathology, offering actionable insights for clinical practice.
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Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Pathologists
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Dedication
- Preface
- Prostate Cancer: Update on Grading and Reporting
- Introduction
- Recent developments and key concepts in Gleason scoring and Grade Groups
- Morphologic issues in Gleason scoring
- Selected situations where prostatic adenocarcinoma should not be graded
- Summary
- Clinics care points
- Disclosure
- Cribriform Lesions of the Prostate Gland
- Background
- Definition of the cribriform gland
- Morphological spectrum of cribriform lesions
- Cribriform prostate adenocarcinoma
- Intraductal carcinoma of the prostate
- Ductal adenocarcinoma
- Atypical intraductal proliferation
- Summary
- Clinics care points
- Disclosure
- Diagnosis and Pathologic Reporting of Prostate Cancer in the Era of MRI-Targeted Prostate Biopsy
- Overview
- Discussion
- Summary
- Clinics care points
- Molecular Genetics of Prostate Cancer and Role of Genomic Testing
- Overview
- Molecular landscape of localized and metastatic prostate cancer
- The role of genomic testing in localized and advanced prostate cancer
- Discussion
- Summary
- Clinics care points
- Update on Flat and Papillary Urothelial Lesions: Genitourinary Pathology Society Consensus Recommendations
- Introduction
- Summary
- Disclosure
- Urothelial Carcinoma: Divergent Differentiation and Morphologic Subtypes
- Overview
- Summary
- Urothelial Carcinoma: Update on Staging and Reporting, and Pathologic Changes Following Neoadjuvant Chemotherapies
- Overview
- Summary
- Molecular Taxonomy and Immune Checkpoint Therapy in Bladder Cancer
- Overview
- Summary
- Clinics care points
- How New Developments Impact Diagnosis in Existing Renal Neoplasms
- Overview
- Summary
- Clinics care points
- Kidney Tumors: New and Emerging Kidney Tumor Entities
- Eosinophilic solid and cystic renal cell carcinoma
- Renal cell carcinoma with fibromyomatous stroma
- Anaplastic lymphoma kinase-rearranged renal cell carcinoma
- Eosinophilic vacuolated tumor
- Low-grade oncocytic tumor
- Thyroid-like follicular renal cell carcinoma
- Biphasic hyalinizing psammomatous renal cell carcinoma
- Summary
- Disclosure
- Testicular Tumors: New Developments in Germ Cell and Sex Cord Stromal Tumors
- Introduction
- Clinics care points
- Clinics care points
- Summary
- Testicular Cancer: Contemporary Updates in Staging
- Overview
- Anatomy and histology of the testis
- Testicular grossing
- Primary tumor: pT
- pTx: primary tumor cannot be assessed
- pT0: no evidence of primary tumor
- pTis: germ cell neoplasia in situ
- pT1: tumors limited to the testis without lymphovascular invasion
- pT2: tumor invades epididymis and/or hilar soft tissue and/or lymphovascular invasion
- pT3: tumor invades spermatic cord with or without lymphovascular invasion
- pT4: invasion of scrotum with or without vascular invasion
- Regional lymph nodes: pN
- pNx: regional lymph nodes cannot be assessed
- pN0: no regional lymph node metastasis
- pN1: less than five positive lymph nodes, with no single lymph node larger than 2 cm and no extranodal extension
- pN2: more than five positive lymph nodes with nodal size ranged between 2 and 5 cm and/or presence of extranodal extension
- pN3: lymph node measuring larger than 5 cm in greatest dimension
- Distant metastasis: pM
- M0: no distant metastasis identified
- M1: distant metastasis present
- Serum tumor markers: S
- Challenging issues that need further studies
- Summary
- Clinics care points
- Applications of Digital and Computational Pathology and Artificial Intelligence in Genitourinary Pathology Diagnostics
- Overview
- Basic principles: computational pathology and artificial intelligence
- Development of artificial intelligence algorithms for pathology
- Development of clinical grade artificial intelligence algorithms
- Computational pathology in genitourinary pathology: prostate cancer as the case of study
- Limitations to the clinical implementation of artificial intelligence
- Fit-for-use clinical artificial intelligence: examples of institutional implementation and validation
- Discussion
- Summary
- Clinics care points
- No. of pages: 240
- Language: English
- Edition: 1
- Volume: 15-4
- Published: November 9, 2022
- Imprint: Elsevier
- Hardback ISBN: 9780323919753
- eBook ISBN: 9780323919760
MZ
Ming Zhou
Affiliations and expertise
Dr. Charles T. Ashworth Professor of Pathology, Director of Anatomic Pathology, UT Southwestern Medical Center, Dallax, Texas