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Genetics and Evolution of Infectious Diseases

Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomi… Read more

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Description

Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches.

Key features

  • Takes an integrated approach to infectious diseases
  • Includes contributions from leading authorities
  • Provides the latest developments in the field

Readership

Researchers in infectious disease, epidemiology, genetics and evolutionary biology and health professionals

Table of contents

Introduction: the need for a holistic approach to infectious diseasesMichel Tibayrenc1. Molecular epidemiology and species definition of pathogensMichel Tibayrenc2. Virus speciesMarc Van Regenmortel 3. Viral evolutionHiroshi Haeno and Yoh 4. Species concept in bacteriaFrederick M. Cohan5. Population structure of pathogenic bacteriaJames Musser & Robert Selander6. Evolution and pathogenesis of fungal organismsTatiana Giraud et al7. Clonal evolutionThierry de Meeus & Franck Prugnolle 8. Co-evolution between host and pathogenAndrew Morgan 9. Elucidating human migration by means of their pathogensThierry Wirth 10. Phylogenetic analysis of pathogensDavid A. Morrison 11. Evolutionary effects of infectious diseases on humansHenry Harpending & Gregory Cochran 12. General human population genetics, major genomic projects and their relevance for biomedical researchMichel Tibayrenc13. Pathogen and vector sequencing projectsBrendan Loftus 14. Proteomics and Host–Pathogen Interactions: a bright future?David Biron et al15. Evolution of antibiotic resistanceMark C. Enright16. Mechanisms of antiviral resistanceAnthony Vere Hodge & Hugh Field, 17. Evolution of resistance to insecticides in disease vectorsPierrick Labbé et al 18. Genetics of major insect vectorsPatricia Dorn et al19. Modern morphometrics of medically important insectsJean-Pierre Dujardin 20. Multilocus sequence typing of pathogensMarcos Perez-Losada et al21. Analysis of pathogen evolution using microarraysWei Zhang22. The bioinformatics revolution and infectious diseasesMark van der Giezen 23. Genomics of infectious diseases and private industryGuy Vernet 24. Pharmacogenetics: The à la carte medicine of tomorrow?Iris Grossman25. Experimental recombination in trypanosomes: its relevance for formal genetics and epidemiologyWendy Gibson et al26. Population genetics of Plasmodium falciparum and the challenge of drug ResistanceColin Sutherland 27. Molecular evolution of Trypanosoma cruzi: a new paradigmal model of basic science?Jenny Tellaria et al28. Identification of Mycobacterium tuberculosis populations using microarrays: does it permit routine molecular epidemiology?Sébastien Gagneux & Marcel Behr29. The evolution and dynamics of methicillin-resistant Staphylococcusaureus: can it be controlled by public health measures?Gerrit Kuhn & Dominique Blanc 30. The origins of human immunodeficiency virus and implications for global EpidemicsEric Delaporte31. Evolution of SARS coronavirus and the relevance of modern molecular EpidemiologyZhengli Shi et al32. Ecology and evolution of avian influenza: the risk of a major pandemicsRon. A.M. Fouchier

Product details

About the editor

MT

Michel Tibayrenc

Dr. Michel Tibayrenc has worked on the evolution of infectious diseases for more than 45 years. He is a director of research emeritus at the French Institut de Recherche pour le Developpement (IRD) and the founder and editor-in-chief emeritus of the Elsevier journal Infection, Genetics and Evolution. From 1996-2021 he was the founder and principal organizer of Elsevier’s international MEEGID congress (Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases). He has held professional appointments in France, Algeria, French Guiana, Bolivia, Thailand, and the United States; is the cofounder of the Bolivian Society of Human Genetics; and is a fellow of the American Association for the Advancement of Science.

Affiliations and expertise
Infectious Diseases and Vectors, Ecology, Genetics, Evolution and Control, IRD Center, Montpellier, France

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