G Protein-Coupled Receptors Part A
- 2nd Edition, Volume 142 - September 29, 2017
- Editor: Arun K. Shukla
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 1 3 3 1 9 - 4
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 3 3 2 0 - 0
G Protein Coupled Receptors, Second Edition, Volume 143, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters… Read more
G Protein Coupled Receptors, Second Edition, Volume 143, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. It contains a wide array of topics about the G protein coupled receptors, as well as updates of chapters from the first edition.
- Contains contributions from experts in the field from across the world
- Covers a wide array of topics on G protein coupled receptors
- Includes analysis based topics
Researchers and students in cell, molecular and developmental biology
1. Generating recombinant peptide ligands for GPCRs and their single step purification
2. Ca2+ release assay to study downstream pathways of GPCR signal transduction
3. Expression and purification of GPCR interacting protein, arrestin
4. Isolation and characterization of chemosensory GPCRs from exosomes
5. Characterization of chemosensory bitter taste receptor signalling
6. Reporter gene assays for investigating GPCR signaling
7. Measuring binding affinity of regulatory motifs (peptides) to purified G proteins
8. Measuring nucleotide exchange on purified G proteins
9. Qualitative and quantitative measurement of GPCR-G protein activity in living cells
10. Computational approaches to study GPCR activation
11. Visualization and quantification of GPCR trafficking in mammalian cells by confocal microscopy
12. Computational studies of βarrestin activation
13. Measuring G protein coupling using Glosensor assay
14. Computational investigations into GPCR dimerization
15. cAMP Assays in GPCR Drug Discovery
16. Assays of adrenal GPCR signaling and regulation: Measuring adrenal beta-arrestin activity in vivo through plasma membrane recruitment
- Edition: 2
- Volume: 142
- Published: September 29, 2017
- Language: English
AS
Arun K. Shukla
Dr. Arun K. Shukla is a world leader in the field of GPCR biology and he is currently a Professor in the Department of Biological Sciences and Bioengineering at the Institute of Technology, Kanpur in India. Dr. Shukla’s research program is focused on understanding the structure, function and regulation of G protein-coupled receptors with a long-term of designing novel therapeutics with minimized side-effects.
Affiliations and expertise
Indian Institute of Technology, Kanpur, IndiaRead G Protein-Coupled Receptors Part A on ScienceDirect