Fundamentals of Bionanomaterials

1st Edition - January 26, 2022
Editors: Ahmed Barhoum, Jaison Jeevanandam, Michael K Danquah
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 2 4 1 4 7 - 9
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 2 4 1 4 8 - 6

Bionanomaterials are molecular materials composed partially or completely of biological molecules, key biological structures, such as proteins, enzymes, viruses, DNA, bi… Read more

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Bionanomaterials are molecular materials composed partially or completely of biological molecules, key biological structures, such as proteins, enzymes, viruses, DNA, biopolymers as well as metal, metal oxides, and carbon nanomaterials with characteristic bioactivity. Bionanomaterials have drawn much attention for their use in a wide range of industrial applications from scaffolds, dental implants, drug delivery, dialysis, biobatteries, biofuel cells, air purification, and water treatment. Therefore, the intensive current research in this area is driven towards the designing and functionalization of bionanomaterials for industrial applications.

Fundamentals of Bionanomaterials covers the fundamental aspects, experimental setup, synthesis, properties, and characterization of the different types of bionanomaterial. It discusses the different structure and unique properties of bionanomaterials that can be obtained by modifying their morphology and composition, highlighting a wide range of fabrication techniques of bionanomaterials and critical processing parameters.

This is an important reference source for all those seeking to gain a solid understanding of the characterization, properties and processing a variety of bionanomaterial classes.

Cover image
Title page
Table of Contents
Copyright
List of contributors
About the editors
Preface
Key features
Chapter 1. Bionanomaterials: definitions, sources, types, properties, toxicity, and regulations
Abstract
1.1 Introduction
1.2 Definitions of bionanomaterials
1.3 Sources of bionanomaterials
1.4 Types of bionanomaterials
1.5 Properties of bionanomaterials
1.6 Toxicity of bionanomaterials
1.7 Regulations of bionanomaterials
1.8 Conclusions
References
Chapter 2. Nature bioinspired and engineered nanomaterials
Abstract
2.1 Introduction
2.2 Inorganic nanomaterials
2.3 Organic nanomaterials
2.4 Carbon nanomaterials
2.5 Hybrid nanomaterials
2.6 Molecular bionanomaterials
2.7 Naturally inspired nanomaterials in human body
2.8 Bone as natural nanomaterials
2.9 Naturally inspired nanomaterials in animals, birds, and insects
2.10 Naturally inspired nanomaterials in plants
2.11 Naturally inspired nanomaterials in microorganisms
2.12 Conclusion and remarks
References
Chapter 3. Culinary spices mediated biogenesis of nanoparticles for cancer and diabetes treatment
Abstract
3.1 Introduction
3.2 Overview of culinary spices
3.3 Extraction of secondary metabolites from culinary spices
3.4 Medicines prepared from spices
3.5 Overview of nanoparticles
3.6 Cancer
3.7 Diabetes
3.8 Future perspective and conclusion
Acknowledgments
References
Chapter 4. Environmental-friendly superhydrophobic bioactive nanocoatings
Abstract
4.1 Introduction
4.2 Fundamentals of superhydrophobic surface engineering
4.3 Bioactive additives as coating material
4.4 Low surface energy nanocoating of bioactive materials
4.5 Challenges in fabrication
4.6 Limitations of bioactive nanocoating materials
4.7 Outlook and future perspectives
References
Chapter 5. Self-assembling of nanobionics: from theory to applications
Abstract
5.1 Introduction and definitions
5.2 Types, applications, and current fields of interest
5.3 Bionic particles
5.4 Self-assembly and molecular self-assembly
5.5 Cases of nature inspired bionic self-assembly
5.6 Self-assembly of proteins and peptides
5.7 Self-assembly of organic molecules and polymers
5.8 Applications of self-assembled nanostructures
5.9 Preparation and characterization of bionic self-assembled structures
5.10 Protein-functionalized gold nanoparticles (P-Au-NP)
5.11 Conclusions and future perspective
References
Chapter 6. Synthesis, properties, and biomedical applications of inorganic bionanomaterials
Abstract
6.1 Introduction
6.2 Classification of inorganic bionanomaterial
6.3 Synthesis of bionanomaterials
6.4 Structural characterizations
6.5 Unique characteristics of inorganic bionanomaterials
6.6 Applications of inorganic bionanomaterials
6.7 Future perspective and conclusion
References
Chapter 7. Polymer nanocomposites for biomedical applications
Abstract
7.1 Introduction
7.2 Polymeric matrices for biomedical application
7.3 Nano-reinforcements
7.4 Nanocomposite preparation
7.5 Biomedical applications of nanocomposites
7.6 Conclusion and future perspective
References
Chapter 8. Lignin nanoparticles and their biomedical applications
Abstract
8.1 Introduction
8.2 Lignin biodegradation
8.3 Environmental factors affecting lignin biodegradation
8.4 Pretreatments and molecular methods engaged in lignin biodegradation
8.5 Biomedical applications of lignin nanoparticles
8.6 Conclusion and future perspective
Acknowledgments
References
Chapter 9. Polymer-based bionanomaterials for targeted drug delivery
Abstract
9.1 Introduction
9.2 Hydrogel-based polymeric bionanomaterials
9.3 Electrospun nanofiber scaffolds
9.4 Nanocellulose polymeric bionanomaterials in nanomedicine
9.5 Nanocarriers in drug delivery systems
9.6 Future perspectives
9.7 Conclusion
Acknowledgment
References
Chapter 10. Cationic nanoparticles for treatment of neurological diseases
Abstract
10.1 Introduction
10.2 Nutraceuticals in neurodegeneration disorders
10.3 Pharmaceutical challenges with nutraceutical delivery systems
10.4 Conventional delivery approaches in brain disorders
10.5 Overview of lipid nanoparticles
10.6 Limitations of lipid nanoparticles
10.7 Role of cationic polymers in brain disease
10.8 Conclusion
References
Chapter 11. Carbon nanomaterials for therapeutic applications
Abstract
11.1 Introduction
11.2 Types of carbon nanomaterials
11.3 Synthesis of carbon nanomaterials
11.4 Functionalization of carbon nanomaterials
11.5 Drug delivery mechanism
11.6 Therapeutic applications of carbon nanomaterial
11.7 Cytotoxicity evaluation
11.8 Future prospective and conclusions
References
Chapter 12. Liposomal bionanomaterials for nucleic acid delivery
Abstract
12.1 Introduction
12.2 Liposomes: structure and composition
12.3 Methods for liposome preparation
12.4 Characterization of liposomes
12.5 Nucleic acid as therapeutics
12.6 Liposomal drug delivery
12.7 Liposomal bionanomaterials: other applications
12.8 Conclusion and future perspective
Acknowledgments
References
Index

Ahmed Barhoum

Dr. Ahmed Barhoum is an Associate Professor of nanomaterials science and Head of the Nanostruc Research Group (Helwan University). He is currently working at the DCU University (Ireland). His research interests include the synthesis of nanomaterials for catalysis, drug delivery, and biosensing. He has won several scientific awards and prizes: Helwan University Prizes (Egypt, 2020 & 2019), CAS Fellowship (China, 2019), IFE Fellowships (France, 2012 & 2018), FWO Fellowships (Belgium, 2015 & 2016), Medastar Erasmus Mundus (Belgium, 2012), Welcome Program (Italy, 2012) and many more. He serves as an expert evaluator for the National Science Centre (NCN, Poland), Czech Science Foundation (GACR, Russia), Swiss National Science Foundation (SNSF, Switzerland), and Innovators Support Fund (ISF, Egypt), among others. He is on the editorial board of Frontiers in Bioengineering and Biotechnology, Frontiers in Nanotechnology, Nanomaterials, and editor of 10 handbooks (Elsevier and Springer Nature), PI/Co-PI of 12 projects, and co-author of 150 publications.

Affiliations and expertise

Head of NanoStruc. Research Group, Chemistry Department, Faculty of Science, Helwan University, Egypt; National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Ireland

Jaison Jeevanandam

Dr. Jaison Jeevanandam is currently working as a senior researcher in Centro De Quimica Da Madeira (CQM – Center for Chemistry), University of Madeira, Portugal. He obtained his Ph.D. in the Department of Chemical Engineering, Faculty of Engineering and Science from Curtin University, Malaysia. He has experience in nanoparticle synthesis, especially in the green synthesis using plant extracts, characterization, cytotoxic analysis of nanoparticles, and in vitro analysis in diabetic models. His current research focuses on the application of nanobiotechnology in the development of nanoformulations for drug delivery systems. He has won several awards, including ‘Best teacher award 2019’ from Academy of competitive exam and research training (ACERT, Chennai), India; Gold medal in 3rd World Invention Innovation Contest (WiC) in 2017 from Korea Invention News (South Korea); Special honor of invention award, 3rd World Invention Innovation Contest (WiC) in 2017 from Toronto International Society of Innovation & Advanced Skills (TISIAS) (Canada). Dr. Jaison has authored +50 articles. Further, Dr. Jaison serves as a journal editor for Bio-integration (China) and International Archives of Biomedical and Engineering Sciences (India), as well as an invited editor for special issue in applied sciences (MDPI), Frontiers in Bioengineering and Biotechnology (Research topic coordinator) and Frontiers in molecular biosciences; and reviewer for 10+ journals.

Affiliations and expertise

Senior Researcher, CQM - Centro De Quimica Da Madeira, MMRG, Universidade Da Madeira, Funchal, Madeira, Portugal

Michael K Danquah

Dr. Danquah is a full Professor and the Director of Chemical Engineering Program at the University of Tennessee, Chattanooga, United States. He is a Chartered Engineer (CEng), Chartered Professional Engineer (CPEng), Chartered Scientist (CSci) and a Fellow of the Institution of Chemical Engineers (IChemE). Dr. Danquah’s research focuses on the utilization of bioprocess and biomolecular engineering principles to develop emerging biopharmaceuticals, biosensing and molecular separation systems; environmental bioremediation systems; and biofuels and bio-products. Dr. Danquah’s research findings are well published and cited with over 230 peer-reviewed journal articles, book chapters, conference publications and technical reports. His research has also resulted in intellectual properties and patent applications, large-scale manufacturing plants, and commercialized products and formulations.

Affiliations and expertise

Chemical Engineering Department, University of Tennessee, Chattanooga, TN, USA

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health

Fundamentals of Bionanomaterials

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Institutional subscription on ScienceDirect

Ahmed Barhoum

Jaison Jeevanandam

Michael K Danquah