Functionalized Nanomaterials for the Management of Microbial Infection

Chapter 1. Resistance to Antibiotics and Antimicrobial Peptides: A Need of Novel Technology to Tackle This Phenomenon

• Abstract
• 1.1 Resistance to Antibiotics
• 1.2 Resistance to Bacteriocins Produced by Gram-Positive Bacteria (GPB)
• 1.3 Conclusion and Prospects
• Acknowledgments
• References

Chapter 2. The Role of the Food Chain in the Spread of Antimicrobial Resistance (AMR)

• Abstract
• 2.1 Introduction
• 2.2 AMR in Foodborne Pathogenic Bacteria
• 2.3 AMR in Food-Related Beneficial Microbes
• 2.4 Routes of Transmission of AMR Throughout the Food Chain
• 2.5 Conclusions
• References

Chapter 3. Penetrating the Bacterial Biofilm: Challenges for Antimicrobial Treatment

• Abstract
• 3.1 Introduction
• 3.2 How Biofilms Pose a Challenge to the Diffusion of Antibiotics
• 3.3 How to Improve Antibiotic Delivery to Biofilm Cells?
• 3.4 Conclusion
• References

Chapter 4. Metal Nanoparticles for Microbial Infection

• Abstract
• 4.1 Introduction
• 4.2 Silver Nanoparticles for Microbial Infection
• 4.3 Copper Nanoparticles for Microbial Infection
• 4.4 Gold Nanoparticles for Microbial Infection
• 4.5 Safety Considerations
• 4.6 Conclusion
• References

Chapter 5. Lipid-Based Nanopharmaceuticals in Antimicrobial Therapy

• Abstract
• 5.1 Nanopharmaceuticals
• 5.2 Lipid-Based Nanopharmaceuticals
• 5.3 Antimicrobial Therapy of Interest
• 5.4 Potential of Nanopharmaceuticals in Treatment of Microbial Infections
• 5.5 Potential of Lipid-Based Nanopharmaceuticals for Antimicrobial Therapy Related to Route of Administration
• 5.6 Toxicity
• 5.7 Current Limitations
• 5.8 Perspectives
• 5.9 Conclusions
• References

Chapter 6. Organic Polymeric Nanomaterials as Advanced Tools in the Fight Against Antibiotic-Resistant Infections

• Abstract
• 6.1 Introduction: Antibiotic Resistance—A Global Threat to Public Health
• 6.2 Nanoantibiotics—A New Paradigm to Fight Against Antibiotic Resistance Bacteria
• 6.3 Polymeric Architectures Relevant to Drug Delivery Applications
• 6.4 Types, Structures, and Supramolecular Morphologies of Polymeric Nanocarriers
• 6.5 Methods for Preparation of Drug-Loaded Polymeric Nanoparticles
• 6.6 Polymer-Based Nanomaterials for Antiinfectious Therapy
• 6.7 Concluding Remarks and Future Perspectives
• References

Chapter 7. Bacteriocins and Nanotechnology

• Abstract
• 7.1 Introduction
• 7.2 Stability of Bacteriocins
• 7.3 Immune Response to Bacteriocins
• 7.4 Preclinical Trials Conducted on Bacteriocins
• 7.5 Delivery Systems
• 7.6 Conclusions
• References

Chapter 8. Graphene-Microbial Interactions

• Abstract
• 8.1 Introduction
• 8.2 Graphene, Graphene Oxide (GO) and Reduced Graphene Oxide (rGO): Production and Characterization
• 8.3 Inhibition of Bacterial Attachment and Antibacterial Activity of Graphene-Coated Surfaces
• 8.4 Interaction of GO and rGO With Bacteria in Suspension
• 8.5 Antibacterial Activity of Nanoparticle Decorated GO and rGO
• 8.6 Conclusion and Perspectives
• Acknowledgments
• References