Free Radicals in Biology V1

List of Contributors

General Preface

Preface

Contents of Volume II

Chapter 1 The Role of Free Radical Reactions in Biological Systems

I. Introduction

II. The Nature of Free Radicals

III. Possible Mechanisms for the Initiation of Radical Reactions in Vivo

IV. Termination Reactions

V. Propagation Reactions

VI. One-Electron versus Two-Electron Transfers

References

Chapter 2 Free Radical Mechanisms of Lipid Damage and Consequences for Cellular Membranes

I. Formation of Free Radicals in Lipids

II. Formation of Free Radicals in Lipid Membranes in Vitro

III. Formation of Free Radicals in Lipid Membranes in Vivo

References

Chapter 3 Applications of Electron Spin Resonance in Biology

I. Introduction

II. A Brief Description of esr as Applied to Free Radicals

III. Some Additional Experimental Considerations

IV. A Few Worked Examples of Biological Free Radicals or Their Reactions Elucidated by esr

References

Chapter 4 Spin Labeling

I. Introduction

II. Essentials of the Method

III. A Look at General Biological Applications

IV. Conclusion

References

Chapter 5 Free Radicals in Photosynthesis

I. Introduction

II. Bacterial Photosynthesis

III. Primary Electron Donor

IV. Primary Electron Acceptor

V. Concluding Remarks

VI. Appendix

References

Chapter 6 Oxygen Radicals, Hydrogen Peroxide, and Oxygen Toxicity

I. Introduction

II. Intermediates of Oxygen Reduction

III. Superoxide Dismutases

IV. Bacterial Superoxide Dismutases

V. The Mitochondrial Superoxide Dismutase

VI. The Biological Significance of Superoxide Dismutase

VII. The Catalases and Peroxidases

VIII. Summary

References

Subject Index