Essentials of Nuclear Medicine and Molecular Imaging
- 7th Edition - August 17, 2018
- Imprint: Elsevier
- Authors: Fred A. Mettler, Milton J. Guiberteau
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 4 8 3 1 9 - 3
Covering both the fundamentals and recent developments in this fast-changing field, Essentials of Nuclear Medicine and Molecular Imaging, 7th Edition, is a must-have resource… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteCovering both the fundamentals and recent developments in this fast-changing field, Essentials of Nuclear Medicine and Molecular Imaging, 7th Edition, is a must-have resource for radiology residents, nuclear medicine residents and fellows, nuclear medicine specialists, and nuclear medicine technicians. Known for its clear and easily understood writing style, superb illustrations, and self-assessment features, this updated classic is an ideal reference for all diagnostic imaging and therapeutic patient care related to nuclear medicine, as well as an excellent review tool for certification or MOC preparation.
- Provides comprehensive, clear explanations of everything from principles of human physiology, pathology, physics, radioactivity, radiopharmaceuticals, radiation safety, and legal requirements to hot topics such as new brain and neuroendocrine tumor agents and hybrid imaging, including PET/MR and PET/CT.
- Covers the imaging of every body system, as well as inflammation, infection and tumor imaging; pearls and pitfalls for every chapter; and pediatric doses and guidelines in compliance with the Image Gently and Image Wisely programs.
- Features a separate self-assessment section on differential diagnoses, imaging procedures and artifacts, and safety issues with unknown cases, questions, answers, and explanations.
- Includes new images and illustrations, for a total of 430 high-quality, multi-modality examples throughout the text.
- Reflects recent advances in the field, including updated nuclear medicine imaging and therapy guidelines • Updated dosimetry values and effective doses for all radiopharmaceuticals with new values from the 2015 International Commission on Radiological Protection • Updated information regarding advances in brain imaging, including amyloid, dopamine transporter and dementia imaging • Inclusion of Ga-68 DOTA PET/CT for neuroendocrine tumors • Expanded information on correlative and hybrid imaging with SPECT/CT • New myocardial agents • and more.
- Contains extensive appendices including updated comprehensive imaging protocols for routine and hybrid imaging, pregnancy and breastfeeding guidelines, pediatric dosages, non-radioactive pharmaceuticals used in interventional and cardiac stress imaging, and radioactivity conversion tables.
- Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
- Cover image
- Title Page
- Table of Contents
- Copyright
- Dedication
- Preface
- Acknowledgments
- 1 Radioactivity, Radionuclides, and Radiopharmaceuticals
- Basic Isotope Notation
- Radionuclide Production
- Radioactive Decay
- Radionuclide Generator Systems
- Radionuclides and Radiopharmaceuticals for Imaging
- Radiopharmacy Quality Control
- Unsealed Radionuclides Used for Therapy
- Suggested Readings
- 2 Instrumentation and Quality Control
- Geiger-Mueller Counter
- Ionization Chamber
- Sodium Iodide Well Counter
- Single Probe Counting Systems
- Dose Calibrator
- Gamma Scintillation Camera
- Single-Photon Emission Computed Tomography (SPECT)
- SPECT/CT
- Positron Emission Tomography (PET)
- PET/CT
- PET/MRI
- Instrumentation Quality Control
- Technical Artifacts
- Suggested Readings
- 3 Central Nervous System
- Radionuclide Brain Imaging
- Cerebrospinal Fluid Imaging
- Suggested Readings
- 4 Thyroid, Parathyroid, and Salivary Glands
- Thyroid Radioiodine Uptake and Imaging
- Iodine-131 Therapy in Benign Thyroid Disease
- Parathyroid Imaging and Localization
- Salivary Gland Imaging
- Suggested Readings
- 5 Cardiovascular System
- Anatomy and Physiology
- SPECT Myocardial Perfusion Imaging
- PET Cardiac Imaging
- Radionuclide Imaging of Cardiac Function
- Suggested Readings
- 6 Respiratory System
- Anatomy and Physiology
- Radiopharmaceuticals
- Technique
- Normal Lung Scan
- Clinical Applications
- Lung Scanning During Pregnancy
- Deep Venous Imaging and Thrombus Detection
- Suggested Readings
- 7 Gastrointestinal Tract
- Liver-Spleen Imaging
- Hepatic Blood Pool Imaging
- Splenic Imaging
- Gastrointestinal Bleeding Studies
- Meckel Diverticulum Imaging
- Hepatobiliary Imaging
- Gastroesophageal Function Studies
- Abdominal Shunt Evaluation
- Suggested Readings
- 8 Skeletal System
- Anatomy and Physiology
- Radiopharmaceuticals
- Technique
- Normal Scan
- Clinical Applications
- Bone Marrow Imaging
- Bone Mineral Measurements
- Palliative Therapy of Painful Osseous Metastases
- Suggested Readings
- 9 Genitourinary System and Adrenal Glands
- Physiology
- Radiopharmaceuticals
- Radionuclide Renal Evaluation
- Clinical Applications of Renal Imaging
- Adrenal Gland Imaging
- Suggested Readings
- 10 Non-PET Neoplasm Imaging and Radionuclide Therapy
- Targeted Tumor Imaging
- Nonspecific Tumor Imaging
- Technetium-99m Sestamibi Tumor Imaging
- Lymphoscintigraphy
- Radionuclide Tumor Antibody Imaging and Therapy
- Suggested Readings
- 11 Hybrid PET/CT Neoplasm Imaging
- 18F-FDG PET Imaging
- Other PET Radionuclides
- Suggested Readings
- 12 Inflammation and Infection Imaging
- Radiolabeled Leukocytes
- Gallium Imaging
- Fluorine-18 Fluorodeoxyglucose PET/CT Imaging
- Future Inflammation Agents
- Suggested Readings
- 13 Authorized User and Radioisotope Safety Issues
- Overview
- NRC and Other Regulatory Agencies
- Types of Licenses
- Dose Limits
- Radiation Safety Committee
- NRC Technical Requirements
- Training Required for Use of Unsealed Byproduct Material
- Training for Sealed Sources for Diagnosis
- Medical Events and Required Reporting
- Maintenance of Records
- Transportation of Radioactive Materials
- Receipt of Radioactive Shipments
- Safe Handling and Administration of Radiopharmaceuticals
- Generator Breakthrough
- PET Radiation Safety
- ALARA and Doses to Patients
- Release of Individuals After Administration of Radionuclides
- Restricted Areas, Radiation Areas, and Signage Posting
- Facility Radiation Survey Policies
- Waste Disposal
- Biological Effects of Ionizing Radiation
- Suggested Readings
- Self-Evaluation
- Unknown Case Sets
- Answers to Unknown Case Sets
- Answers to Unknown Case Sets
- Appendices
- Appendix A Characteristics of Radionuclides for Imaging and Therapy
- Appendix B.1 Radioactivity Conversion Table for International System (SI) Units (Becquerels to Curies)
- Appendix B.2 Radioactivity Conversion Table for International System (SI) Units (Curies to Becquerels)
- Appendix C.1 Technetium-99m Decay and Generation Tables
- Appendix C.2 Other Radionuclide Decay Tables
- Appendix D Injection Techniques and Pediatric Dosages
- Appendix E Sample Techniques for Nuclear Imaging
- Brain Death or Cerebral Blood Flow Scan
- SPECT Brain Perfusion Imaging
- Cisternogram
- Thyroid Scan (99mTc-Pertechnetate)
- Thyroid Scan and Uptake (Iodine-123)
- Thyroid Cancer Scan
- Parathyroid Scan
- Rest Gated Equilibrium Ventriculography
- SPECT Myocardial Perfusion Imaging
- Exercise Protocol Using a Bruce Multistage or Modified Bruce Treadmill Exercise Protocol
- Dipyridamole Pharmacologic Stress Procedure
- Adenosine Pharmacologic Stress Procedure
- Regadenoson Pharmacologic Stress Procedure
- Pulmonary Ventilation Scan (Xenon)
- Pulmonary Ventilation Scan (DTPA Aerosol)
- Pulmonary Perfusion Scan
- Liver and Spleen Scan
- SPECT/CT Liver and Spleen Imaging
- Hepatobiliary Scan
- Meckel Diverticulum Scan
- Gastrointestinal Bleeding Scan
- Esophageal Transit
- Gastroesophageal Reflux/Aspiration
- Gastric Emptying
- Peritoneovenous (LeVeen) Ascites Shunt Patency
- Salivary Gland Imaging
- Bone Scan (Technetium-99m)
- SPECT Bone Imaging
- Bone Marrow Scan
- Renal Blood Flow Scan
- Renal Scan (A) Cortical Imaging
- Renal Scan (B) Glomerular Filtration
- Renal Scan (C) Tubular Function
- Diuretic (Lasix) Renogram
- Captopril Renogram for Diagnosis of Renovascular Hypertension
- Radionuclide Cystogram in Children
- MIBG Scan for Pheochromocytoma and Neuroblastoma
- Gallium Scan for Tumor or Infection
- Somatostatin Receptor Scan With Indium-111 Pentetreotide
- Lymphoscintigraphy (Sentinel Node Localization)
- Molecular Breast Imaging With Breast-Specific Gamma Camera (CZT Detectors)
- Leukocyte (White Blood Cell) Scan
- PET/CT Tumor Imaging With Fluorine-18 Fluorodeoxyglucose (FDG)
- PET Cardiac Imaging With Fluorine-18 Fluorodeoxyglucose (FDG)
- PET Brain Imaging With Fluorine-18 Fluorodeoxyglucose (FDG)
- PET Amyloid Brain Imaging
- PET Cardiac Rest/Stress Imaging With Rubidium-82 or Nitrogen-13 Ammonia
- Bone Scan PET/CT (Fluorine-18 Sodium Fluoride)
- Red Blood Cell Labeling Techniques
- Appendix F Nonradioactive Pharmaceuticals in Nuclear Medicine
- Suggested Readings
- Appendix G Pregnancy and Breastfeeding
- Pregnancy
- Breastfeeding
- Appendix H.1 General Considerations for Hospitalized Patients Receiving Radionuclide Therapy
- Appendix H.2 Special Considerations and Requirements for Iodine-131 Therapy
- Nursing Instructions
- Release From the Hospital
- Appendix I Emergency Procedures for Spills of Radioactive Materials and Special Circumstances
- Spills of Radioactive Materials
- Minor Spills
- Major Spills
- Surface Contamination Limits
- Emergency Surgery of Patients Who Have Received Therapeutic Amounts of Radionuclides
- Emergency Autopsy of Patients Who Have Received Therapeutic Amounts of Radionuclides
- Index
- Edition: 7
- Published: August 17, 2018
- Imprint: Elsevier
- No. of pages: 560
- Language: English
- Hardback ISBN: 9780323483193
FM
Fred A. Mettler
Affiliations and expertise
Emeritus Professor, Department of Radiology, University of New Mexico, School of Medicine, Health Sciences Center, Albuquerque, New MexicoMG
Milton J. Guiberteau
Affiliations and expertise
Professor, Department of Radiology, Baylor College of Medicine, Texas Medical Center, Houston, TexasRead Essentials of Nuclear Medicine and Molecular Imaging on ScienceDirect