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Essentials of Biochemistry
- 3rd Edition - September 9, 2021
- Authors: U. Satyanaryana, U. Chakrapani
- Language: English
- Paperback ISBN:9 7 8 - 8 1 - 3 1 2 - 6 4 9 7 - 3
- eBook ISBN:9 7 8 - 8 1 - 3 1 2 - 6 4 9 8 - 0
This book, Essentials of Biochemistry (Third Edition-Revised and Updated), serves as a Textbook of Biochemistry for the students of Dental, Pharmacy, Physiotherapy, Nursing, Ho… Read more
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Request a sales quoteThis book, Essentials of Biochemistry (Third Edition-Revised and Updated), serves as a Textbook of Biochemistry for the students of Dental, Pharmacy, Physiotherapy, Nursing, Homeopathy, Ayurveda, Medical Laboratory Technology, Veterinary, Agriculture, Biotechnology, Home Science, Microbiology, Genetics and other Biosciences.
- serves as a Textbook of Biochemistry for the students of Dental, Pharmacy, Physiotherapy, Nursing, Homeopathy, Ayurveda, Medical Laboratory Technology, Veterinary, Agriculture, Biotechnology, Home Science, Microbiology, Genetics and other Biosciences.
- is written in a lucid style with the subject being at present as an engaging story growing from elementary information to the most recent advances, and with theoretical discussions being supplemented with illustrations, tables, medical concepts/clinical correlates and case studies for easy and the standing of Biochemistry.
- contains medically/clinically oriented biochemistry with inputs from MD (Biochemistry) and MD (General Medicine) Professors.
- has essence of the subject in a nutshell for a quick review by all categories of students (including Medical), learning biochemistry.
- is a boon to students afraid of complicated structures, since it gives complete information and most recent advances in Biochemistry with minimal and essential structures.
- describes a wide variety of case studies (40) with medical correlations. The case studies are listed at the end of relevant chapters for immediate reference, quick review and better understanding of Biochemistry.
- contains the basics (Bioorganic and Biophysical Chemistry, Tools of Biochemistry, Immunology and Genetics) for beginners to learn easily Biochemistry; Principles of Practical Biochemistry, Clinical Biochemistry Laboratory etc.
- Cover image
- Title page
- Table of Contents
- Copyright
- PREFACE
- ACKNOWLEDGEMENTS
- List of Illustrations
- List of Tables
- SECTION ONE: Chemical Constituents of Life
- Chapter 1: BIOMOLECULES AND THE CELL
- THE CELL
- EUKARYOTIC CELL
- INTEGRATION OF CELLULAR FUNCTIONS
- Chapter 2: CARBOHYDRATES
- CLASSIFICATION OF CARBOHYDRATES
- MONOSACCHARIDES— STRUCTURAL ASPECTS
- STRUCTURE OF GLUCOSE
- REACTIONS OF MONOSACCHARIDES
- GLYCOSIDES
- DERIVATIVES OF MONOSACCHARIDES
- DISACCHARIDES
- POLYSACCHARIDES
- HOMOPOLYSACCHARIDES
- HETEROPOLYSACCHARIDES
- MUCOPOLYSACCHARIDES
- GLYCOPROTEINS
- Chapter 3: LIPIDS
- FATTY ACIDS
- ESSENTIAL FATTY ACIDS
- TRANS FATTY ACIDS
- TRIACYLGLYCEROLS
- PROPERTIES OF TRIACYLGLYCEROLS
- PHOSPHOLIPIDS
- GLYCOLIPIDS
- LIPOPROTEINS
- STEROIDS
- CHOLESTEROL
- AMPHIPATHIC LIPIDS
- Chapter 4: PROTEINS AND AMINO ACIDS
- STANDARD AMINO ACIDS
- AMINO ACIDS
- STRUCTURE OF PROTEINS
- PRIMARY STRUCTURE OF PROTEIN
- SECONDARY STRUCTURE OF PROTEIN
- TERTIARY STRUCTURE OF PROTEIN
- QUATERNARY STRUCTURE OF PROTEIN
- PROPERTIES OF PROTEINS
- DENATURATION
- CLASSIFICATION OF PROTEINS
- BIOLOGICALLY IMPORTANT PEPTIDES
- Chapter 5: NUCLEIC ACIDS AND NUCLEOTIDES
- NUCLEOTIDES
- BIOLOGICALLY IMPORTANT NUCLEOTIDES AND THEIR FUNCTIONS
- STRUCTURE OF NUCLEOTIDES
- STRUCTURE OF DNA
- DNA DOUBLE HELIX
- OTHER TYPES OF DNA STRUCTURE
- STRUCTURE OF RNA
- TYPES OF RNA
- CATALYTIC RNAs—RIBOZYMES
- Chapter 6: ENZYMES
- NOMENCLATURE AND CLASSIFICATION
- CHEMICAL NATURE OF ENZYMES
- FACTORS AFFECTING ENZYME ACTIVITY
- ACTIVE SITE
- ENZYME INHIBITION
- ENZYME SPECIFICITY
- COENZYMES
- MECHANISM OF ENZYME ACTION
- MECHANISM OF ENZYME CATALYSIS
- REGULATION OF ENZYME ACTIVITY IN THE LIVING SYSTEM
- UNITS OF ENZYME ACTIVITY
- PLASMA/SERUM ENZYMES
- DIAGNOSTIC IMPORTANCE OF ENZYMES
- ISOENZYMES
- ENZYME PATTERN IN DISEASES
- Chapter 7: VITAMINS
- INDIVIDUAL VITAMINS
- VITAMIN A
- BIOCHEMICAL FUNCTIONS
- VITAMIN D
- METABOLISM AND BIOCHEMICAL FUNCTIONS
- VITAMIN E
- VITAMIN K
- VITAMIN C (ASCORBIC ACID)
- THIAMINE (VITAMIN B1)
- RIBOFLAVIN (VITAMIN B2)
- NIACIN
- PYRIDOXINE (VITAMIN B6)
- BIOTIN
- PANTOTHENIC ACID
- FOLIC ACID
- COBALAMIN (VITAMIN B12)
- INTERRELATION BETWEEN FOLIC ACID AND VITAMIN B12—FOLATE TRAP OR METHYL TRAP HYPOTHESIS
- VITAMIN LIKE COMPOUNDS
- CHOLINE
- INOSITOL
- LIPOIC ACID
- PARA AMINOBENZOIC ACID
- BIOFLAVONOIDS
- ANTIVITAMINS
- SECTION TWO: Physiological Biochemistry
- Chapter 8: DIGESTION AND ABSOROPTION
- CARBOHYDRATES
- PROTEINS
- LIPIDS
- ABNORMALITIES RELATED TO DIGESTION AND ABSORPTION
- Chapter 9: PLASMA PROTEINS
- ALBUMIN
- GLOBULINS
- α1-ANTITRYPSIN
- HAPTOGLOBIN
- CERULOPLASMIN
- ACUTE PHASE PROTEINS
- IMMUNOGLOBULINS
- CLASSES OF IMMUNOGLOBULINS
- MULTIPLE MYELOMA
- BLOOD CLOTTING
- Chapter 10: HEMOGLOBIN AND PORPHYRINS
- HEMOGLOBIN
- FUNCTIONS OF HEMOGLOBIN
- BOHR EFFECT
- EFFECT OF 2,3-BISPHOSPHOGLYCERATE ON O2 AFFINITY OF Hb
- HEMOGLOBIN DERIVATIVES
- ABNORMAL HEMOGLOBINS
- SICKLE-CELL ANEMIA OR SICKLE-CELL HEMOGLOBIN
- THALASSEMIAS
- PORPHYRINS
- BIOSYNTHESIS OF HEME
- PORPHYRIAS
- DEGRADATION OF HEME TO BILE PIGMENTS
- JAUNDICE
- JAUNDICE DUE TO GENETIC DEFECTS
- Chapter 11: BIOLOGICAL OXIDATION
- BIOENERGETICS
- HIGH-ENERGY COMPOUNDS
- BIOLOGICAL OXIDATION
- ELECTRON TRANSPORT CHAIN
- OXIDATIVE PHOSPHORYLATION
- MECHANISM OF OXIDATIVE PHOSPHORYLATION
- SECTION THREE: Metabolisms
- Chapter 12: INTRODUCTION TO METABOLISM
- Chapter 13: METABOLISM OF CARBOHYDRATES
- GLYCOLYSIS
- RAPOPORT-LEUBERING CYCLE
- CONVERSION OF PYRUVATE TO ACETYL COA
- CITRIC ACID CYCLE
- GLUCONEOGENESIS
- GLYCOGEN METABOLISM
- GLYCOGENESIS
- GLYCOGENOLYSIS
- FUTILE (SUBSTRATE) CYCLES
- GLYCOGEN STORAGE DISEASES
- HEXOSE MONOPHOSPHATE SHUNT
- URONIC ACID PATHWAY
- METABOLISM OF GALACTOSE
- METABOLISM OF FRUCTOSE
- METABOLISM OF AMINO SUGARS
- Chapter 14: METABOLISM OF LIPIDS
- FATTY ACID OXIDATION
- KETONE BODIES
- BIOSYNTHESIS OF FATTY ACIDS
- SYNTHESIS OF TRIACYLGLYCEROLS
- METABOLISM OF PHOSPHOLIPIDS
- METABOLISM OF CHOLESTEROL
- CHOLESTEROL BIOSYNTHESIS
- DEGRADATION OF CHOLESTEROL
- HYPERCHOLESTEROLEMIA
- LIPOPROTEINS
- DISORDERS OF PLASMA LIPOPROTEINS
- FATTY LIVER
- LIPOTROPIC FACTORS
- ATHEROSCLEROSIS
- ALCOHOL METABOLISM
- Chapter 15: METABOLISM OF AMINO ACIDS
- AMINO ACID POOL
- METABOLISM OF AMINO ACIDS—GENERAL ASPECTS
- TRANSAMINATION
- DEAMINATION
- METABOLISM OF AMMONIA
- UREA CYCLE
- METABOLISM OF INDIVIDUAL AMINO ACIDS
- GLYCINE
- PHENYLALANINE AND TYROSINE
- DISORDERS OF TYROSINE (PHENYLALANINE) METABOLISM
- TRYPTOPHAN
- SULFUR AMINO ACIDS
- METABOLISM OF METHIONINE
- ONE-CARBON METABOLISM
- BRANCHED CHAIN AMINO ACIDS
- HISTIDINE, PROLINE AND ARGININE
- GLUTAMATE AND GLUTAMINE
- FATE OF CARBON SKELETON OF AMINO ACIDS
- BIOGENIC AMINES
- Chapter 16: INTEGRATION OF METABOLISM
- ORGAN SPECIALIZATION AND METABOLIC INTEGRATION
- METABOLISM IN STARVATION
- Chapter 17: METABOLISM OF NUCLEOTIDES
- BIOSYNTHESIS OF PURINE RIBONUCLEOTIDES
- DEGRADATION OF PURINE NUCLEOTIDES
- DISORDERS OF PURINE METABOLISM
- BIOSYNTHESIS OF PYRIMIDINE RIBONUCLEOTIDES
- Chapter 18: MINERAL METABOLISM
- CALCIUM
- FACTORS REGULATING PLASMA Ca LEVEL
- DISEASE STATES
- PHOSPHORUS
- TEETH
- Development of teeth
- MAGNESIUM
- SODIUM
- POTASSIUM
- CHLORINE
- IRON
- COPPER
- IODINE
- ZINC
- COBALT
- FLUORINE
- SELENIUM
- CHROMIUM
- SECTION FOUR: Clinical Biochemistry and Nutrition
- Chapter 19: HORMONES
- CLASSIFICATION OF HORMONES
- cAMP—THE SECOND MESSENGER
- HYPOTHALAMIC AND PITUITARY HORMONES
- HYPOTHALAMIC HORMONES
- ANTERIOR PITUITARY HORMONES
- I The growth hormone-prolactin group
- Abnormalities of GH production
- II The glycoprotein hormones
- POSTERIOR PITUITARY HORMONES
- THYROID HORMONES
- HORMONES OF ADRENAL CORTEX
- HORMONES OF ADRENAL MEDULLA
- HORMONES OF GONADS
- ANDROGENS
- ESTROGENS
- PROGESTERONE
- THE MENSTRUAL CYCLE
- MENOPAUSE
- GASTROINTESTINAL HORMONES
- Chapter 20: ORGAN FUNCTION TESTS
- LIVER FUNCTION TESTS
- BILIRUBIN
- SERUM ENZYMES DERIVED FROM LIVER
- JAUNDICE
- KIDNEY (RENAL) FUNCTION TESTS
- CLEARANCE TESTS
- Chapter 21: WATER, ELECTROLYTE AND ACID–BASE BALANCE
- WATER AND LIFE
- WATER TURNOVER AND BALANCE
- ELECTROLYTE BALANCE
- ACID-BASE BALANCE
- MAINTENANCE OF BLOOD pH
- DISORDERS OF ACID-BASE BALANCE
- Chapter 22: TISSUE PROTEINS AND BODY FLUIDS
- CONNECTIVE TISSUE PROTEINS
- COLLAGEN
- ELASTIN
- FIBRILLIN
- PROTEOGLYCANS
- KERATINS
- CONTRACTILE PROTEINS
- STRUCTURE OF MUSCLE
- MUSCLE PROTEINS
- ACTIN
- MYOSINS
- PROTEIN MISFOLDING AND DISEASES
- BODY FLUIDS
- MILK
- COMPOSITION OF MILK
- CEREBROSPINAL FLUID (CSF)
- AMNIOTIC FLUID
- AQUEOUS HUMOR
- PLEURAL FLUID
- Chapter 23: NUTRITION
- NUTRITION AND ENERGY SUPPLY
- UTILIZATION OF ENERGY IN MAN
- BASAL METABOLIC RATE
- SPECIFIC DYNAMIC ACTION
- PHYSICAL ACTIVITY OF THE BODY
- NUTRITIONAL IMPORTANCE OF CARBOHYDRATES
- FIBER IN NUTRITION
- NUTRITIONAL IMPORTANCE OF LIPIDS
- ESSENTIAL FATTY ACIDS
- NUTRITIONAL IMPORTANCE OF PROTEINS
- NITROGEN BALANCE
- NUTRITIONAL IMPORTANCE OF VITAMINS AND MINERALS
- RECOMMENDED DIETARY ALLOWANCES (RDA)
- BALANCED DIET
- NUTRITIONAL DISORDERS
- PROTEIN–ENERGY MALNUTRITION
- OTHER NUTRITIONAL DISORDERS
- OBESITY
- METABOLIC SYNDROME
- SECTION FIVE: Molecular Biology and Biotechnology
- Chapter 24: DNA-REPLICATION, RECOMBINATION, AND REPAIR
- REPLICATION OF DNA
- REPLICATION IN PROKARYOTES
- REPLICATION IN EUKARYOTES
- INHIBITORS OF DNA REPLICATION
- CELL CYCLE AND DNA REPLICATION
- TELOMERES AND TELOMERASE
- RECOMBINATION
- DAMAGE AND REPAIR OF DNA
- TYPES OF DNA DAMAGES
- MUTATIONS
- REPAIR OF DNA
- DEFECTS IN DNA REPAIR AND CANCER
- Chapter 25: TRANSCRIPTION AND TRANSLATION
- GENOME
- TRANSCRIPTOME
- PROTEOME
- TRANSCRIPTION
- TRANSCRIPTION IN PROKARYOTES
- TRANSCRIPTION IN EUKARYOTES
- POST-TRANSCRIPTIONAL MODIFICATIONS
- REVERSE TRANSCRIPTION
- TRANSLATION
- GENETIC CODE
- PROTEIN BIOSYNTHESIS
- I REQUIREMENT OF THE COMPONENTS
- II ACTIVATION OF AMINO ACIDS
- III PROTEIN SYNTHESIS PROPER
- INITIATION OF TRANSLATION
- ELONGATION OF TRANSLATION
- TERMINATION OF TRANSLATION
- INHIBITORS OF PROTEIN SYNTHESIS
- IV CHAPERONES AND PROTEIN FOLDING
- V POST-TRANSLATIONAL MODIFICATIONS OF PROTEINS
- PROTEIN TARGETING
- MITOCHONDRIAL DNA, TRANSCRIPTION AND TRANSLATION
- Chapter 26: REGULATION OF GENE EXPRESSION
- GENE REGULATION—GENERAL
- Chapter 27: RECOMBINANT DNA AND BIOTECHNOLOGY
- BASIC PRINCIPLES OF rDNA TECHNOLOGY
- MOLECULAR TOOLS OF GENETIC ENGINEERING
- HOST CELLS—THE FACTORIES OF CLONING
- VECTORS—THE CLONING VEHICLES
- METHODS OF GENE TRANSFER
- GENE CLONING STRATEGIES
- BASIC TECHNIQUES IN GENETIC ENGINEERING
- ISOLATION AND PURIFICATION OF NUCLEIC ACIDS
- NUCLEIC ACID BLOTTING TECHNIQUES
- SOUTHERN BLOTTING
- NORTHERN BLOTTING
- DOT-BLOTTING
- DNA SEQUENCING
- POLYMERASE CHAIN REACTION (DNA AMPLIFICATION)
- APPLICATIONS OF PCR
- GENE LIBRARIES
- DNA IN DISEASE DIAGNOSIS AND MEDICAL FORENSICS
- DNA FINGERPRINTING OR DNA PROFILING
- PHARMACEUTICAL PRODUCTS OF DNA TECHNOLOGY
- RECOMBINANT VACCINES
- RECOMBINANT VACCINES FOR COVID-19
- TRANSGENIC ANIMALS
- BIOTECHNOLOGY AND SOCIETY
- BENEFITS OF BIOTECHNOLOGY
- ELSI OF BIOTECHNOLOGY
- Chapter 28: HUMAN GENOME PROJECT
- THE BIRTH AND ACTIVITY OF HUMAN GENOME PROJECT
- MAPPING OF THE HUMAN GENOME
- APPROACHES FOR GENOME SEQUENCING
- HUMAN GENOME SEQUENCE—RESULTS SUMMARISED
- BENEFITS/APPLICATIONS OF HUMAN GENOME SEQUENCING
- ETHICS AND HUMAN GENOME
- SECTION SIX: Current Topics
- Chapter 29: GENE THERAPY
- APPROACHES FOR GENE THERAPY
- EX VIVO GENE THERAPY
- VECTORS IN GENE THERAPY
- THERAPY FOR ADENOSINE DEAMINASE DEFICIENCY
- IN VIVO GENE THERAPY
- ANTIGENE AND ANTISENSE THERAPY
- THE FUTURE OF GENE THERAPY
- Chapter 30: BIOINFORMATICS
- BROAD COVERAGE OF BIOINFORMATICS
- COMPONENTS OF BIOINFORMATICS
- BIOINFORMATICS AND THE INTERNET
- BIOLOGICAL DATABASES
- APPLICATIONS OF BIOINFORMATICS
- Chapter 31: METABOLISM OF XENOBIOTICS (DETOXIFICATION)
- MECHANISM OF DETOXIFICATION
- Oxidation
- Role of cytochrome P450
- Salient features of cytochrome P450
- Reduction
- Hydrolysis
- Conjugation
- Chapter 32: PROSTAGLANDINS AND RELATED COMPOUNDS
- LEUKOTRIENES
- Chapter 33: BIOLOGICAL MEMBRANES AND TRANSPORT
- Chapter 34: FREE RADICALS AND ANTIOXIDANTS
- SOURCES AND GENERATION OF FREE RADICALS
- HARMFUL EFFECTS OF FREE RADICALS
- ANTIOXIDANTS IN BIOLOGICAL SYSTEM
- Chapter 35: ENVIRONMENTAL BIOCHEMISTRY
- ATMOSPHERIC (CLIMATIC) CHANGES
- EXPOSURE TO COLD
- EXPOSURE TO HEAT
- ENVIRONMENTAL POLLUTION
- AIR POLLUTION
- WATER POLLUTION
- ORGANIC POLLUTANTS
- INORGANIC POLLUTANTS
- NOISE POLLUTION
- TOXIC COMPOUNDS IN FOODSTUFFS
- CARCINOGENS
- Chapter 36: INSULIN, GLUCOSE HOMEOSTASIS, AND DIABETES MELLITUS
- INSULIN
- GLUCAGON
- REGULATION OF BLOOD GLUCOSE LEVEL (HOMEOSTASIS OF BLOOD GLUCOSE)
- HYPOGLYCEMIA
- CLASSIFICATION OF DIABETES MELLITUS
- Chapter 37: CANCER
- ETIOLOGY
- MOLECULAR BASIS OF CANCER
- Chapter 38: ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS)
- SECTION SEVEN: Basics to Learn Biochemistry
- Chapter 39: INTRODUCTION TO BIOORGANIC CHEMISTRY
- ISOMERISM
- Chapter 40: OVERVIEW OF BIOPHYSICAL CHEMISTRY
- ACIDS AND BASES
- BUFFERS
- SOLUTIONS
- COLLOIDAL STATE
- DIFFUSION
- OSMOSIS
- DONNAN MEMBRANE EQUILIBRIUM
- VISCOSITY
- SURFACE TENSION
- ADSORPTION
- ISOTOPES
- Chapter 41: TOOLS OF BIOCHEMISTRY
- CHROMATOGRAPHY
- ELECTROPHORESIS
- PHOTOMETRY—COLORIMETER AND SPECTROPHOTOMETER
- FLAME PHOTOMETRY
- ULTRACENTRIFUGATION
- RADIOIMMUNOASSAY
- ENZYME-LINKED IMMUNOSORBENT ASSAY
- HYBRIDOMA TECHNOLOGY
- Chapter 42: IMMUNOLOGY
- INNATE IMMUNITY
- THE IMMUNE SYSTEM
- ORGANIZATION OF IMMUNE SYSTEM
- CELLS OF THE IMMUNE SYSTEM
- MAJOR HISTOCOMPATIBILITY COMPLEX
- THE COMPLEMENT SYSTEM
- THE IMMUNE RESPONSE
- CYTOKINES
- IMMUNITY IN HEALTH AND DISEASE
- AUTOIMMUNE DISEASES
- ORGAN TRANSPLANTATION
- CANCERS
- AIDS
- Chapter 43: GENETICS
- BRIEF HISTORY AND DEVELOPMENT OF GENETICS
- BASIC PRINCIPLES OF HEREDITY IN HUMANS
- PATTERNS OF INHERITANCE
- GENETIC DISEASES IN HUMANS
- EUGENICS
- SELF-ASSESSMENT EXERCISES
- APPENDICES
- ABBREVIATIONS USED IN THIS BOOK
- PRACTICAL BIOCHEMISTRY-PRINCIPLES
- CLINICAL BIOCHEMISTRY LABORATORY
- CASE STUDIES WITH BIOCHEMICAL CORRELATIONS
- INDEX
- No. of pages: 450
- Language: English
- Edition: 3
- Published: September 9, 2021
- Imprint: Elsevier India
- Paperback ISBN: 9788131264973
- eBook ISBN: 9788131264980
US
U. Satyanaryana
Affiliations and expertise
M.Sc., Ph.D., F.I.C., F.A.C.B., F.A.C.B.I
Professor of Biochemistry & Director (Research)
Dr. Pinnamaneni Siddhartha Institute of Medical Sciences
(Dr. NTR University of Health Sciences)
Chinaoutpalli, Gannavaram (Mdl)
Krishna (Dist), A.P., IndiaUC
U. Chakrapani
Affiliations and expertise
M.B.B.S., M.S., D.N.B.