Esophageal Cancer ,An Issue of Thoracic Surgery Clinics

1st Edition, Volume 32-4 - October 21, 2022
Editors: Jonathan Yeung, Elena Elimova
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 4 9 8 9 - 0
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 4 9 9 0 - 6

In this issue of Thoracic Surgery Clinics, guest editors Drs. Jonathan Yeung and Elena Elimova bring their considerable expertise to the topic of Esophageal Cancer. Nearly 20,000… Read more

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In this issue of Thoracic Surgery Clinics, guest editors Drs. Jonathan Yeung and Elena Elimova bring their considerable expertise to the topic of Esophageal Cancer. Nearly 20,000 new cases of esophageal cancer are diagnosed each year in the U.S. alone. In this issue, top experts provide a timely update of this perennially important topic with coverage of pathology, genetics, staging, adjuvant therapies, and surgical management, as well as two special articles on controversies in esophageal cancer.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
Barrett’s Esophagus and Esophageal Adenocarcinoma: A Histopathological Perspective
Key points
Glossary list
Introduction
Barrett’s esophagus
Esophageal adenocarcinoma
Clinics care points
Disclosure
Esophageal Cancer Genetics and Clinical Translation
Key points
Introduction: clinical utility of molecular biomarkers
Epidemiology, risk factors, and pathogenesis
Molecular classification
Molecular distinction of esophageal adenocarcinoma from squamous cell carcinoma
Molecular distinction of esophageal from gastric cancers
Clinical translation: molecular biomarkers to predict the risk of progression in Barrett esophagus
Summary and future directions
Clinics care points
Esophageal Cancer Staging
Key points
Background
Staging modalities
Staging modalities
Esophagogastroduodenoscopy
Endoscopic ultrasound
Endoscopic mucosal resection
Computed tomography and PET
Other clinical staging modalities
Post-neoadjuvant therapy stage groups
Pathologic stage groups
Disclosure
Neoadjuvant Therapy in Esophageal Cancer
Key points
Introduction
Discussion
Recommendations
Conclusion/summary
Clinics care points
Disclosure
Adjuvant Therapies for Esophageal Cancer
Key points
Introduction
Adjuvant therapy for esophageal adenocarcinoma
Preoperative chemoradiotherapy
Summary
Clinics care points
Disclosure
Immune Checkpoint Blockade and Targeted Therapies in Esophageal Cancer
Key points
Introduction
Esophageal adenocarcinoma
Esophageal squamous cell carcinoma
Immunotherapy in the perioperative and adjuvant setting
Future targets
Future directions
Summary
Clinics care points
Endoscopic Management of Esophageal Cancer
Key points
Introduction
Curative management of esophageal cancer
Clinics care points
Lymph Node Dissection for Esophageal Squamous Cell Carcinoma
Key points
Introduction
The extent of lymph node distribution
The extent of lymphadenectomy
The efficacy of lymphadenectomy
The recurrent laryngeal nerve lymph node dissection
Techniques and technologies in recurrent laryngeal nerve lymph node dissection
The role of cervical lymphadenectomy
Thoracic duct resection as part of lymphadenectomy
Summary
Clinics care points
Colon Interposition for Esophageal Cancer
Key points
Introduction
Summary
Clinics care points
Disclosure
Supercharged Jejunal Interposition
Key points
Background
History
Nature of the problem
Anatomy
Preoperative planning
Checklist preparation and patient positioning
Procedural checklist
Postprocedure care
Summary
Clinics care points
Ongoing Controversies in Esophageal Cancer I: Feeding Tubes, Pyloroplasty, Thoracic Duct Clipping
Key points
Introduction
Ongoing Controversies in Esophageal Cancer II: Gastrectomy versus Esophagectomy for Siewert Type II Esophageal Adenocarcinoma
Key points
Introduction
Gastroesophageal junctional adenocarcinoma-definitions and classifications
Diagnosis and staging assessment of esophagogastric junction tumors
Summary
Clinics care points

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Esophageal Cancer ,An Issue of Thoracic Surgery Clinics

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Jonathan Yeung

Elena Elimova