Equine Genetic Diseases, An Issue of Veterinary Clinics of North America: Equine Practice
- 1st Edition, Volume 36-2 - July 19, 2020
- Imprint: Elsevier
- Editor: Carrie Finno
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 7 0 8 5 9 - 3
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 0 8 6 0 - 9
This issue of Veterinary Clinics: Equine Practice, guest edited by Dr. Carrie Finno, focuses on Equine Genetic Diseases. Topics include: Genetics, Genomics, and Emergent Precision… Read more
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Request a sales quoteThis issue of Veterinary Clinics: Equine Practice, guest edited by Dr. Carrie Finno, focuses on Equine Genetic Diseases. Topics include: Genetics, Genomics, and Emergent Precision Medicine 12 years post Equine Reference Genome; Equine SNP Genotyping Arrays; Next-generation Sequencing; Genetic Testing in the Horse; Genetics of Cardiovascular Disease; Genetics of Respiratory Disease; Genetics of Neurological Disease; Genetics of Immune Disease; Genetics of Orthopedic Disease; Genetics of Ocular Disease; Genetics of Skin Disease; Genetics of Endocrine and Metabolic Disease; Genetics of Muscle Disease; Genetics of Laminitis; Genetics of Reproductive Diseases; and Genetics of Behavioral Traits.
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Preface
- Genetics, Genomics, and Emergent Precision Medicine 12 Years After the Equine Reference Genome Was Published
- Key points
- What is a reference genome?
- What is annotation?
- Paradigm shift in research
- Crystal ball gazing
- Equine Genotyping Arrays
- Key points
- Introduction
- Design and implementation of equine genotyping arrays
- Usefulness in association mapping
- Population genomics
- Imputation
- Forward compatibility with EquCab3.0
- Next-Generation Sequencing in Equine Genomics
- Key points
- Introduction
- Building genomic resources for the horse
- Technology
- Sequencing platforms
- Sequence reads
- Applications
- Data generation and handling
- Validation of results
- Future directions
- Genetic Testing in the Horse
- Key points
- Introduction and history of equine genetic testing
- Genetic testing for parentage and identity
- Genetic tests for coat color and associated disorders
- Genetic testing for genetic diseases
- Genetic testing for performance traits
- Standardization for diagnostic tests
- Future developments in equine genetic testing
- Unraveling the Genetics Behind Equid Cardiac Disease
- Key points
- Introduction
- Summary
- Genetics of Equine Respiratory Disease
- Key points
- Introduction
- Tympany of the guttural pouches
- Recurrent laryngeal neuropathy
- Miscellaneous upper airway disorders
- Equine asthma
- Exercise-induced pulmonary hemorrhage
- Infectious diseases of the respiratory tract
- Summary
- Genetics of Equine Neurologic Disease
- Key points
- Introduction
- Neurologic disorders with known mutations
- Summary
- Genetics of Immune Disease in the Horse
- Key points
- Introduction and scope
- Summary
- Genetics of Equine Orthopedic Disease
- Key points
- Introduction
- Osteochondrosis
- Degenerative disorders of the joints
- Tendon and ligament defects
- Defects of the skeleton and adnexal structures
- Summary
- Genetics of Equine Ocular Disease
- Key points
- Introduction
- Multiple congenital ocular anomalies
- Congenital stationary night blindness
- Equine recurrent uveitis
- Ocular squamous cell carcinoma
- Ocular manifestations of equine diseases caused by known genetic mutations
- Inherited ocular disease with unknown genetic causes
- Summary
- Genetics of Skin Disease in Horses
- Key points
- Introduction
- Genetics of Equine Endocrine and Metabolic Disease
- Key points
- Animal models in complex disease genetics
- Metabolic syndrome
- Dopaminergic neurodegeneration
- Summary
- Genetics of Equine Muscle Disease
- Key points
- Introduction
- Hyperkalemic periodic paralysis
- Glycogen branching enzyme deficiency
- Type 1 polysaccharide storage myopathy
- Chronic management
- Malignant hyperthermia
- Myosin heavy chain myopathies
- Clinical signs
- Pathophysiology
- Management
- Multiple genetic mutations
- Summary
- Genetics and Signaling Pathways of Laminitis
- Key points
- Introduction
- Summary
- Genetics of Equine Reproductive Diseases
- Key points
- Introduction
- Reproductive disorders caused by chromosome mutations
- Molecular genetics of reproductive disorders
- Summary
- Genetics of Equine Behavioral Traits
- Key points
- Introduction
- How much of horse behavior is heritable?
- Molecular genetics of horse behavior
- Stereotypic behaviors: are they genetic or are they learned?
- Summary
- Edition: 1
- Volume: 36-2
- Published: July 19, 2020
- Imprint: Elsevier
- Language: English
- Hardback ISBN: 9780323708593
- eBook ISBN: 9780323708609