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Epilepsy Surgery: Paradigm Shifts, An Issue of Neurosurgery Clinics of North America
- 1st Edition, Volume 35-1 - November 23, 2023
- Editors: Jimmy Yang, Mark R. Richardson
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 3 1 6 7 - 7
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 3 1 6 8 - 4
In this issue of Neurosurgery Clinics, guest editors Drs. Jimmy Yang and R. Mark Richardson bring their considerable expertise to the topic of Epilepsy Surgery: Paradigm Shifts. T… Read more
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Request a sales quoteIn this issue of Neurosurgery Clinics, guest editors Drs. Jimmy Yang and R. Mark Richardson bring their considerable expertise to the topic of Epilepsy Surgery: Paradigm Shifts. Top experts in the field explore the underutilization of epilepsy surgery as a public health crisis, and recent paradigm shifts in how epilepsy surgery is conceptualized that may help bring significant improvement to greater numbers of people with drug-resistant epilepsy.
- Contains 16 relevant, practice-oriented topics, including pediatric neurostimulation and practice evolution; brain stimulation in pediatric generalized epilepsy; imaging and SEEG functional networks to guide epilepsy surgery; sensing-enabled deep brain stimulation in epilepsy; thalamic stimulation to prevent impaired consciousness; gene therapy for epilepsy; and more.
- Provides in-depth clinical reviews on paradigm shifts in epilepsy surgery, offering actionable insights for clinical practice.
- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Neurosurgery, Neurology
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Preface
- Section I: Focus on Quality of Life
- Pediatric Neurostimulation and Practice Evolution
- Key points
- Introduction
- Surgical approaches: diagnostic
- Surgical approaches: therapeutic
- Summary
- Clinics care points
- Deep Brain Stimulation for Children with Generalized Epilepsy
- Key points
- Background: the current state of deep brain stimulation for treating drug-resistant epilepsy
- Rationale for using deep brain stimulation to treat children with generalized epilepsy
- Clinical efficacy of deep brain stimulation for treating children with generalized-onset seizures/drug-resistant epilepsy
- Beyond seizure freedom: what about quality of life, carer burden, and cognition?
- Responsive neurostimulation
- Availability and barriers to adoption
- Patient and carer perceptions: nuances of deep brain stimulation for epilepsy in children
- Recommendations for further research
- Summary
- Clinics care points
- Neurostimulation for Generalized Epilepsy: Should Therapy be Syndrome-specific?
- Key points
- Introduction
- Scope of this review
- What epilepsy syndrome does the patient have?
- What brain networks are involved?
- What is the optimal stimulation target?
- What is the optimal stimulation paradigm?
- What is the plan for adjusting stimulation over time?
- Summary
- Clinics care points
- Funding
- Epilepsy Surgery for Cognitive Improvement in Epileptic Encephalopathy
- Key points
- Introduction
- Cognitive impact of epilepsy surgery versus continued medication
- Predictors of cognitive improvement after pediatric epilepsy surgery
- Epilepsy surgery for developmental and epileptic encephalopathies
- Considerations in epilepsy surgery evaluation for epileptic encephalopathy
- Case example
- Measures of success
- Summary
- Section II: Network Surgery and the Evolution of SEEG
- Imaging and Stereotactic Electroencephalography Functional Networks to Guide Epilepsy Surgery
- Key points
- Introduction
- Functional magnetic resonance imaging
- Diffusion-weighted imaging
- Intracranial electroencephalography
- Multimodal
- Discussion
- Summary
- Clinics care points
- Interpretation of the Intracranial Electroencephalogram of the Human Hippocampus
- Key points
- Introduction
- Interpretation of the hippocampal intracranial electroencephalogram
- Summary
- Evolution of SEEG Strategy: Stanford Experience
- Key points
- Technological and methodological changes in invasive monitoring
- Evolution in invasive monitoring strategy
- Summary
- Evolution of Stereo-Electroencephalography at Massachusetts General Hospital
- Key points
- Introduction and history
- Implications of a seizure network approach
- Implementing the seizure network approach at Massachusetts General Hospital
- Illustrative case
- Clinics care points
- Summary
- The Value of Stereo-electroencephalography in Temporal Lobe Epilepsy: Huashan Experience
- Key points
- Introduction
- Stereo-electroencephalography in unilateral temporal lobe epilepsy
- Stereo-electroencephalography in MRI-negative temporal lobe epilepsy
- Stereo-electroencephalography in bilateral temporal lobe epilepsy
- Stereo-electroencephalography in temporal plus epilepsy
- Stereo-electroencephalography in pseudo temporal lobe epilepsy
- Discussion
- Clinics care points
- Funding information
- Conflicts of interest
- Acute Effect of Vagus Nerve Stimulation in Patients with Drug-Resistant Epilepsy: A Preliminary Exploration via Stereoelectroencephalogram
- Key points
- Introduction
- Methods
- Results
- Discussion
- Summary
- Statement
- Clinical Care Points
- Section III: Cutting Edge Technologies
- Sensing-Enabled Deep Brain Stimulation in Epilepsy
- Key points
- Introduction
- Anterior nucleus of the thalamus involvement in epilepsy networks
- Deep brain stimulation sensing technology in epilepsy
- Institutional experience with deep brain stimulation sensing in epilepsy
- Summary
- Clinics care points
- Utility of Chronic Intracranial Electroencephalography in Responsive Neurostimulation Therapy
- Key points
- Introduction
- Design of the responsive neurostimulation system
- Chronic recording and storage of neurostimulator data
- Role of chronic data in therapy optimization
- Adjunctive applications of chronic data
- Summary
- Clinics care points
- Electrode Development for Epilepsy Diagnosis and Treatment
- Key points
- History
- Discussion: changing materials and methods for recordings
- Advances in brain surface technologies
- Advances in intraparenchymal technologies
- A changing landscape of academic and industrial interest and regulatory considerations
- Summary
- Clinics care points
- Interneuron Transplantation for Drug-Resistant Epilepsy
- Key points
- Introduction
- Developmental origin and function of cortical interneurons
- Basic studies of the functional integration of transplanted interneurons
- Transplantation of rodent interneurons in preclinical epilepsy models
- Preclinical studies of human stem cell-derived interneurons
- A first-in-human trial of interneuron transplantation
- Knowledge gaps and barriers to the effective clinical applications of interneuron transplantation
- Summary
- Clinics care points
- Funding
- No. of pages: 240
- Language: English
- Edition: 1
- Volume: 35-1
- Published: November 23, 2023
- Imprint: Elsevier
- Hardback ISBN: 9780443131677
- eBook ISBN: 9780443131684
JY
Jimmy Yang
Affiliations and expertise
Assistant Professor of Neurological Surgery, The Ohio State University Wexner Medical CenterMR
Mark R. Richardson
Affiliations and expertise
Professor, Department of Otolaryngology/Head and Neck Surgery; Dean, School of Medicine, Oregon Health & Sciences University, Portland, OR, USA
Pappas Associate Professor of Neurosciences, Department of Neurosurgery, Harvard Medical School, Director of Functional Neurosurgery, Massachusetts, General Hospital