Epigenetics and miRNA in Neurodegenerative Diseases
From Molecular Mechanisms to Clinical Applications
- 1st Edition - September 1, 2026
- Latest edition
- Editors: Lance R. McMahon, Dharmendra Kumar Khatri, Balachandar Vellingiri
- Language: English
Epigenetics and miRNA in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications explores the crucial role of epigenetic modifications and microRNAs in the… Read more
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- Integrates perspectives from neuroscience, molecular biology, clinical medicine, and bioinformatics
- Covers fundamental molecular mechanisms, disease specific applications, and translational research, appealing to both researchers and clinicians
- Provides practical examples of epigenetic and miRNA research as applied to neurodegenerative diseases, aiding in real-world implementation
1. Introduction to Epigenetics and miRNA in neurodegenerative diseases
2. Epigenetic Mechanisms in the Nervous System
3. miRNA Biogenesis and Function in Brain Health
Section II: Epigenetics and miRNA in Specific Neurodegenerative Disorders
4. Alzheimer’s Disease: Epigenetic and miRNA Contributions
5. Parkinson’s Disease: The Role of Epigenetic Modifications
6. Huntington’s Disease: Epigenetic and Post-Transcriptional Control
7. Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD): Molecular Crosstalk
8. Multiple Sclerosis: Epigenetic and miRNA Influence on Neuroinflammation
Section III: Translational and Clinical Applications
9. Epigenetic Biomarkers in Neurodegenerative Diseases
10. miRNA-Based Therapeutics: Challenges and Opportunities
11. Pharmacological and Nutritional Epigenetics in Neuroprotection
12. Gene Editing and Epigenetic Engineering Approaches
13. Artificial Intelligence and Computational Epigenomics in Neurodegeneration
Section IV: Future Perspectives and Ethical Considerations
14. Personalized Medicine in Neurodegenerative Diseases: The Role of Epigenetics and miRNA
15. Ethical, Legal, and Social Implications of Epigenetic and miRNA-Based Therapies
- Edition: 1
- Latest edition
- Published: September 1, 2026
- Language: English
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Lance R. McMahon
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Dharmendra Kumar Khatri
Dr. Dharmendra Kumar Khatri is an Associate Professor in the Department of Pharmacology, NIMS Institute of Pharmacy at NIMS University Rajasthan, Jaipur, India.
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Balachandar Vellingiri
Dr. Balachandar Vellingiri currently is investigating various neurological diseases and developing human induced pluripotent stem cells (HiPSCs). Exploring the cutting-edge molecular, cellular, and translational neuroscience approaches, he aims to unravel disease mechanisms, identify therapeutic targets, and develop innovative interventions to slow or reverse neurological diseases. His expertise is on several techniques such as molecular cytogenetics, pathway analysis, and techniques in developing HiPSCs and Brain organoids, especially for neurological diseases.