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Eosinophilic Gastrointestinal Diseases, An Issue of Immunology and Allergy Clinics of North America
- 1st Edition, Volume 44-2 - April 5, 2024
- Editors: Glenn T. Furuta, Dan Atkins
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 1 2 9 0 3 - 2
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 2 9 0 4 - 9
In this issue of Immunology and Allergy Clinics, guest editors Drs. Glenn T. Furuta and Dan Atkins bring their considerable expertise to the topic of Eosinophilic Gastroint… Read more
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Request a sales quoteIn this issue of Immunology and Allergy Clinics, guest editors Drs. Glenn T. Furuta and Dan Atkins bring their considerable expertise to the topic of Eosinophilic Gastrointestinal Diseases. Top experts provide a multilayered examination of the current state of knowledge in the field, compiling an issue that serves as a convenient reference for the evaluation and management of eosinophilic esophagitis (EoE) and eosinophilic gastrointestinal diseases (EGIDs).
- Contains 21 relevant, practice-oriented topics including epidemiological and clinical clues to the etiology of EoE; dietary management of EoE; quality of life with EoE; diversity, equity, and inclusion in EoE; clinical presentation of patients with EGIDs; pharmacologic management of EGIDs; and more.
- Provides in-depth clinical reviews on eosinophilic gastrointestinal diseases, offering actionable insights for clinical practice.
- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Gastroenterologists
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Foreword
- Preface
- Pathophysiology of Eosinophilic Esophagitis
- Key points
- Introduction
- Genetic contributions
- Early-life environmental exposures
- Role of the epithelium in eosinophilic esophagitis pathogenesis
- Summary
- Clinics care points
- Pathophysiology and Clinical Impact of Esophageal Remodeling and Fibrosis in Eosinophilic Esophagitis
- Key points
- Introduction
- Defining esophageal remodeling in eosinophilic esophagitis
- Summary
- Clinics care points
- Epidemiologic and Clinical Clues to the Etiology of Eosinophilic Esophagitis
- Key points
- Introduction
- Epidemiologic clues
- Genetic risk factors
- Early life
- Later life and environmental exposures
- Clinical clues
- Summary/future directions
- Clinics care points
- Clinical Evaluation of the Child with Eosinophilic Esophagitis
- Key points
- Introduction
- Epidemiology
- Clinical symptoms
- Physical examination
- Endoscopic findings
- Histologic features and diagnostic criteria
- Complications of eosinophilic esophagitis
- Treatment
- Evaluation of atopic comorbidities
- Novel methods for disease monitoring in eosinophilic esophagitis
- Relationship with oral immunotherapy
- Summary
- Recognition and Management of Feeding Dysfunction in the Pediatric Patient with Eosinophilic Esophagitis
- Key points
- Clinical presentation of feeding dysfunction in children with eosinophilic gastrointestinal disorders
- Symptoms suggestive of feeding dysfunction
- Assessment
- Feeding treatment
- Case studies
- Summary
- Clinics care points
- Clinical Evaluation of the Adult with Eosinophilic Esophagitis
- Key points
- Introduction
- Definition
- Epidemiologic features and demographic characteristics
- Assessment of symptoms in adults with eosinophilic esophagitis
- Physical examination of adults with eosinophilic esophagitis
- Laboratory analyses
- Endoscopic assessment of adults with eosinophilic esophagitis
- Particularities of biopsy-sampling in eosinophilic esophagitis
- Imaging methods
- Esophageal stress tests—the emerging “ergometry” for gastroenterologists to demask and quantify hidden dysphagia?
- Natural history, complications, and indications for treatment of adult eosinophilic esophagitis
- Outlook
- Clinics care points
- Endoscopic Features of Eosinophilic Esophagitis
- Introduction
- Clinics care points
- Histopathology of Eosinophilic Esophagitis
- Key points
- Background
- Dietary Management of Eosinophilic Esophagitis
- Key points
- Introduction
- Background
- Elemental diet: the most effective modality
- Allergy testing–based diet
- Empiric elimination diets
- Four-food elimination diet and step-up approaches
- Randomized trials with diet therapies in eosinophilic esophagitis
- How to discuss diet therapy with patients
- Nutrition assessment
- Implementing diet therapy
- Empiric elimination diets
- Making dietary therapy work for long-term maintenance
- Summary
- Clinics care points
- Pharmacologic Management of Eosinophilic Esophagitis
- Key points
- Introduction
- Proton pump inhibitors
- Potassium-competitive acid blockers
- Corticosteroids
- Biologics
- Summary
- Clinics care points
- Health-Related Quality of Life in Patients with Eosinophilic Esophagitis
- Key points
- Introduction
- Measurement of health-related quality of life in eosinophilic esophagitis
- Determinants of quality of life in adult patients with eosinophilic esophagitis
- Impact of treatment on quality of life
- Summary
- Clinics care points
- The Relationship Between Eosinophilic Esophagitis and Immunotherapy
- Key points
- Introduction
- Definitions of immunotherapy
- Background
- Discussion
- Outcomes after discontinuation of oral immunotherapy
- Aeroallergens and eosinophilic esophagitis
- Proposed options for management
- Summary
- Clinics care points
- Embracing Diversity, Equity, Inclusion, and Accessibility in Eosinophilic Gastrointestinal Diseases
- Key points
- Introduction
- Impact of race, ethnicity, and socioeconomic factors on eosinophilic gastrointestinal diseases
- Disparities in rural communities
- Future directions: where do we go from here?
- Summary
- Clinics care points
- Pathophysiology of Non-Esophageal Eosinophilic Gastrointestinal Disorders
- Key points
- Introduction
- Definitions and challenges
- Epidemiology
- Nomenclature
- Allergic etiology
- Cellular and molecular pathophysiology
- Summary
- Clinics care points
- Role of Mast Cells in Eosinophilic Gastrointestinal Diseases
- Key points
- Introduction
- Summary
- Clinics care points
- Associations of Eosinophilic Gastrointestinal Disorders with Other Gastrointestinal and Allergic Diseases
- Key points
- Introduction
- Allergy and eosinophilic gastrointestinal disorders
- Other gastrointestinal conditions and eosinophilic gastrointestinal disorders
- Summary
- Clinics care points
- Clinical Presentation of Patients with Eosinophilic Gastrointestinal Diseases beyond Eosinophilic Esophagitis
- Key points
- Clinical presentation of mucosal subtype of eosinophilic gastrointestinal diseases beyond eosinophilic esophagitis
- Clinical presentation of muscular subtype of non-EoE EGIDs
- Clinical presentation of subserosal subtype of non-EoE EGIDs
- Summary
- Clinics care points
- Endoscopic Features of Eosinophilic Gastrointestinal Diseases
- Key points
- Introduction
- Endoscopic scores in eosinophilic esophagitis
- Endoscopic scores in non-EoE eosinophilic gastrointestinal diseases
- The role of endoscopic features in diagnosis and follow-up of eosinophilic gastrointestinal diseases
- Endoscopic interventions
- The role of endoscopy in eosinophilic esophagitis-like diseases
- Area of uncertainty
- Future perspective
- Histopathology of Eosinophilic Gastrointestinal Diseases Beyond Eosinophilic Esophagitis
- Key points
- Background
- Pathogenesis of eosinophilic gastrointestinal diseases
- Histopathologic evaluation of mucosal biopsies for the diagnosis of eosinophilic gastrointestinal disease
- Influence of eosinophil-depleting biologic agents on histopathology in eosinophilic gastrointestinal disease
- Dietary Management of Non-EoE Eosinophilic Gastrointestinal Diseases
- Key points
- Background
- Current evidence: allergy evaluation of patients with non–eosinophilic esophagitis eosinophilic gastrointestinal diseases
- Therapeutic options: diet as a treatment modality
- Discussion
- Summary
- Clinics care points
- Pharmacologic Management of Non–Eosinophilic Esophagitis Eosinophilic Gastrointestinal Diseases
- Key points
- Introduction
- Corticosteroid treatments
- Other non-biologic treatments
- Biologic treatments
- Summary and future directions
- Clinics care points
- No. of pages: 240
- Language: English
- Edition: 1
- Volume: 44-2
- Published: April 5, 2024
- Imprint: Elsevier
- Hardback ISBN: 9780443129032
- eBook ISBN: 9780443129049
GF
Glenn T. Furuta
Affiliations and expertise
Gastrointestinal Eosinophilic Disease Program, National Jewish Health, The Children’s Hospital Denver, Aurora, CO, USADA
Dan Atkins
Affiliations and expertise
Department of Pediatrics
Division of Pediatric Allergy and Immunology
National Jewish Health
The Children’s Hospital Denver
University of Colorado Denver School of Medicine
Denver, CO, USA