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Engineering of Biomaterials for Drug Delivery Systems
Beyond Polyethylene Glycol
1st Edition - January 27, 2018
Editor: Anilkumar Parambath
Hardback ISBN:9780081017500
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eBook ISBN:9780081017517
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Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong… Read more
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Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo. Chapters then focus on alternative polymer systems for drug delivery systems. Finally, nanoparticles and future perspectives are examined. This book is a valuable resource for scientists and researchers in biomaterials, pharmaceuticals and nanotechnology, and all those who wish to broaden their knowledge in this field.
Provides a self-contained work for the field of biomaterials for drug delivery
Summarizes the current knowledge on PEGylation and strategies for bypassing it
Presents research on an important, though under-represented issue in biomaterials
Written by a world-class team of research scientists, engineers and clinicians
Researchers and scientists in biomaterials for drug delivery, biomaterials synthesis, pharmaceuticals and nanotechnology
1. PEGylated ‘stealth’ liposomes
2. PEGylated proteins
3. PEGylation and anti-PEG antibodies
4. Poly (zwitterions)
5. Poly (glycerols)
6. Poly (oxazolines)
7. Poly (aminoacids)
8. Poly (acylamides) and related systems
9. Poly (vinylpyrrolidones)
10. Sugar based systems (trehalose)
11. Polypeptide alternatives (PASylation and XTen) to PEG
12. DDS based on non-immunogenic biopolymers
13. Non-PEGylated nanoparticles
14. Summary and future perspectives
No. of pages: 404
Language: English
Published: January 27, 2018
Imprint: Woodhead Publishing
Hardback ISBN: 9780081017500
eBook ISBN: 9780081017517
AP
Anilkumar Parambath
Dr Anilkumar Parambath is Senior Manager and Head of Capsules Product R&D, ACG Capsules, Mumbai, India. Prior to this he was a Principal Investigator for Performance and Specialty Materials at Syngene International Ltd, Bangalore India, where he worked on developing various elastomers, silicones, acrylics and other polymers for biomedical applications. He completed his PhD in Chemistry (Polymer Science) at the University of Kerala, India, and spend 7 years conducting post-doctoral research at Clemson University, USA, French atomic Energy Commission (CEA), France, and the University of British Columbia, Canada. He has successfully led RnD programs of several innovation initiatives in academic and industry settings. Dr. Parambath has edited two books on polymer biomaterials in drug delivery applications, including one with Elsevier in the Woodhead Publishing in Biomaterials series, and has published many books chapters and journal articles. He has two patents to his name.