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Energy Metabolism and the Regulation of Metabolic Processes in Mitochondria
1st Edition - January 1, 1972
Editor: Myron Mehlman
9 7 8 - 0 - 3 2 3 - 1 4 1 2 5 - 3
Energy Metabolism and the Regulation of Metabolic Processes in Mitochondria contains papers presented at the 1972 symposium on metabolic regulation, held at the University of… Read more
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Energy Metabolism and the Regulation of Metabolic Processes in Mitochondria contains papers presented at the 1972 symposium on metabolic regulation, held at the University of Nebraska Medical School in Omaha, Nebraska. The contributors provide alternative views and ideas in some aspects of metabolic regulation directly concerned with mitochondrial function. Separating 16 papers into chapters, this book first discusses the general aspects of control of the biological energy regulation and the kinetic and thermodynamic control of mitochondrial electron transport and energy coupling. It then covers significant topics on citric acid cycle, including its replenishment and depletion; anion transport and regulation; dynamics and substrate compartmentation; and feedback control. Other chapters examine the mechanisms of gluconeogenesis, lipogenesis, redox reaction, and phosphorylation in the mitochondria. Discussions on hormonal regulation of selected enzyme system directly related to mitochondrial function are provided in the concluding chapters. Biochemists, physiologists, pharmacologists, physicians, researchers, and all others interested in the concepts of mitochondrial function will find this book of great value.
ContributorsPrefaceMechanism and Control of Oxidative PhosphorylationKinetic Control of Electron FlowThermodynamic Control of Mitochondrial Energy CouplingReplenishment and Depletion of Citric Acid Cycle Intermediates in MuscleAnion Transport and the Regulation of the Citric Acid CycleIs There an Organization of Krebs Cycle Enzymes in the Mitochondrial Matrix?Citric Acid Cycle Dynamics and Substrate Compartmentation in Mitochondria from Rabbit Heart and BrainThe Significance of Mitochondrial Phosphoenolpyruvate Formation in the Regulation of Gluconeogenesis in Guinea Pig LiverProduction and Utilization of ATP and the Regulation of Lipogenesis in Adipose Tissue Liver Metabolite Content, Redox and Phosphorylation States in Rats Fed Diets Containing 1, 3-Butanediol and EthanolFeedback Control of the Citric Acid CycleSources and Disposition of Aerobically-Generated Intermediates in Heart MuscleHormonal Regulation of Pyruvate Metabolism in Rat Liver MitochondriaPyruvate Dehydrogenase Complex: Structure, Function, and RegulationReductive Carboxylation of α-Oxoglutarate by Mitochondria from Livers of Normal, Diabetic, and Fat-Fed RatsProperties of Mitochondrial ATPaseSubject Index