
Endocrine Emergencies
- 1st Edition - May 13, 2021
- Imprint: Elsevier
- Author: Alexander L. Shifrin
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 7 6 0 9 7 - 3
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 6 0 9 8 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 6 0 9 9 - 7
Endocrine emergencies are often potentially life-threatening and can be easily overlooked in patients with no history of endocrine disease. Endocrine Emergencies is a practical… Read more

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Request a sales quoteGuides clinicians on how to recognize, diagnose, and treat each condition using up-to-date diagnostic techniques and therapeutics.
Provides full-color, state-of-the-art coverage of key topics such as acute thyrotoxicosis and thyroid storm, ocular emergencies in Graves’ ophthalmopathy, diabetic ketoacidosis, hypopituitarism, postoperative thyroid surgical emergencies, pheochromocytoma, and much more.
Features separate chapters on emergencies related to neuroendocrine tumors, pregnant patients, and pediatric patients.
Includes sections on emergency overview, symptoms, diagnosis, and treatment in each chapter.
Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
- Cover Image
- Title Page
- Copyright
- Dedication
- Acknowledgments
- Preface
- Contributors
- Table of Contents
- Part 1 Thyroid
- Chapter 1 Severe Thyrotoxicosis and Thyroid Storm
- Chapter Outline
- Abstract
- Introduction
- Pathophysiology of Thyrotoxicosis and Thyroid Storm
- Evaluation of Patients for Thyrotoxicosis
- Socioeconomic Factors
- Follow-up After Discharge
- Conclusions
- References
- Chapter 2 Amiodarone-Induced Thyrotoxicosis
- Chapter Outline
- Abstract
- Introduction
- Pathogenesis and Subtypes
- Diagnostic Evaluation and Classification
- Approach to Management
- Adjunct Therapies
- Role of Amiodarone Discontinuation and Resumption
- Role of Thyroidectomy in Management
- Conclusions
- References
- Chapter 3 Ocular Emergencies in Graves' Ophthalmopathy
- Chapter Outline
- Abstract
- Introduction
- Demographics
- Clinical Evaluation
- External Pathology
- Anterior Segment Pathology
- Posterior Segment Pathology
- Conclusion
- References
- Chapter 4 Myxedema Coma
- Chapter Outline
- Introduction
- Pathophysiology
- Clinical Presentation
- Diagnosis
- Management
- Myxedema Coma and Surgery
- General Supportive Measures
- Prognosis
- References
- Chapter 5 Acute Suppurative Thyroiditis
- Chapter Outline
- Abstract
- Background
- Bacterial Infection
- Fungal Infection
- Granulomatous Infections
- Laboratory Testing and Diagnostic Imaging for Acute Suppurative Thyroiditis
- Treatment of AST and Recommended Follow-up
- References
- Chapter 6 Thyrotoxic Periodic Paralysis: A Review and Suggestions for Treatment
- Chapter Outline
- Abstract
- Introduction
- Clinical Presentation
- Diagnosis
- Differential Diagnosis
- Pathophysiology
- Genetic Aspects
- Acute Treatment
- Definitive Treatment
- Anesthesia Considerations
- Summary
- References
- Part 2 Postoperative Thyroid Surgical Emergencies
- Chapter 7 Recurrent Laryngeal Nerve Paralysis – Management of Recurrent Laryngeal Nerve Injuries
- Chapter Outline
- Abstract
- Introduction
- Intraoperative Management of the RLN With Thyroid Carcinoma Invasion
- Evaluation of the Outcomes of the RLN Reconstruction
- References
- Chapter 8 Post-Thyroidectomy Emergencies: Management of Tracheal and Esophageal Injuries
- Chapter Outline
- Abstract
- Introduction
- Trachea
- Esophagus
- References
- Chapter 9 Radioactive Iodine (131I) Thyroid Ablation and the Salivary Glands
- Abstract
- Chapter Outline
- Introduction
- Reassessment of 131I Therapy
- Adverse Effects of 131I
- Case Reports
- Treatment
- References
- Part 3 Parathyroid
- Chapter 10 Hypercalcemic Crisis
- Chapter Outline
- Abstract
- Introduction
- Etiology/Pathophysiology
- Presentation, Evaluation, and Diagnosis
- Summary
- References
- Chapter 11 Hypocalcemic Crisis: Acute Postoperative and Long-Term Management of Hypocalcemia
- Chapter Outline
- Abstract
- Introduction
- Clinical Presentation
- Physical Examination
- Diagnostic Tests
- Prevention of Postoperative Hypocalcemia
- Prophylactic Postoperative Calcium and Vitamin D Replacement
- Medical Management of Acute and Chronic Postoperative Hypocalcemia
- Chronic Management of Hypocalcemia
- References
- Part 4 Adrenal Glands
- Chapter 12 Acute Adrenal Hypertensive Emergencies: Pheochromocytoma, Cushing's, Hyperaldosteronism
- Chapter Outline
- Abstract
- Introduction
- Pheochromocytoma/Paraganglioma (PPGL)
- Primary Aldosteronism
- Cushing's Syndrome
- References
- Chapter 13 Pheochromocytoma: Perioperative and Intraoperative Management
- Chapter Outline
- Abstract
- Incidence, Clinical Significance, and Diagnosis
- Preoperative Management
- Anesthetic Preoperative Assessment and Optimization
- Anesthetic Preparation and Goals for the Operating Room
- Anesthetic Induction and Monitoring
- Anesthetic Maintenance
- Anesthetic Management of Intraoperative Hypertension and Hypotension
- Postoperative Management
- Postoperative Follow-Up
- Conclusion
- References
- Chapter 14 Acute Adrenal Insufficiency
- Chapter Outline
- Abstract
- Introduction
- Clinical Presentation
- Diagnosis
- Management of Acute Adrenal Insufficiency
- Chronic Management of Adrenal Insufficiency and Prevention of Adrenal Crisis
- References
- Part 5 Endocrine Pancreas and Pancreatic Neuroendocrine Tumors
- Chapter 15 Diabetic Emergencies: Ketoacidosis, Hyperglycemic Hyperosmolar State, and Hypoglycemia
- Chapter Outline
- Abstract
- Diabetic Ketoacidosis
- Hyperglycemic Hyperosmolar State
- Hypoglycemia
- Conclusion
- References
- Chapter 16 Pancreatic Neuroendocrine Emergencies in the Adult (Gastrinoma, Insulinoma, Glucagonoma, VIPoma, Somatostatinoma, and PPoma/Nonfunctional Tumors)
- Chapter Outline
- Abstract
- Overview
- Gastrinoma
- Insulinoma
- Glucagonoma
- VIPoma
- Somatostatinoma
- PPoma/Nonfunctional Neuroendocrine Tumors
- References
- Part 6 Neuroendocrine Tumors: Gastrointestinal Neuroendocrine Tumors
- Chapter 17 Carcinoid Syndrome and Carcinoid Crisis
- Chapter Outline
- Abstract
- Introduction
- Definition
- Incidence
- Risk Factors
- Current Understanding of Pathophysiology
- Treatment With Somatostatin Analogues (Octreotide)
- Treatment With Vasopressors, Including β-Adrenergic Agonists
- Conclusion
- References
- Part 7 Pituitary
- Chapter 18 Postsurgical and Posttraumatic Hyponatremia
- Chapter Outline
- Abstract
- Introduction
- Definition and Classification of Hyponatremia
- Arginine Vasopressin
- General Treatment Considerations for Hyponatremia
- Hyponatremia in the Surgical and TBI Setting: Preoperative Hyponatremia
- Hyponatremia in the Surgical and TBI Setting: Postoperative Hyponatremia
- Neurosurgical Patients
- Traumatic Brain Injury Patients
- Evaluation of Postoperative and Post-TBI Hyponatremia
- Treatment of Postoperative and Post-TBI Hyponatremia
- Summary
- References
- Chapter 19 Diabetes Insipidus and Acute Hypernatremia
- Chapter Outline
- Abstract
- Introduction
- Physiology of Water and Sodium Homeostasis
- Etiologies of Hypernatremia
- Clinical Presentation of Hypernatremia
- Diagnostic Evaluation
- Management
- Prognosis
- References
- Chapter 20 Hypopituitarism
- Chapter Outline
- Abstract
- Introduction
- Central Adrenal Insufficiency
- Central Hypothyroidism
- Central Hypogonadism
- Growth Hormone Deficiency
- Prolactin Deficiency
- Interactions Between Hormones
- Special Situations
- Diagnosis of Hypopituitarism During Pregnancy
- Treatment of Hypopituitarism During Pregnancy
- References
- Chapter 21 Pituitary Apoplexy
- Chapter Outline
- Abstract
- Introduction
- Epidemiology
- Pathophysiology
- Precipitating Factors
- Clinical Presentation
- Diagnosis
- Management
- Outcomes
- Conclusion
- References
- Part 8 Endocrine Emergencies During Pregnancy
- Chapter 22 Endocrine Emergencies in Obstetrics
- Chapter Outline
- Abstract
- Thyroid Storm
- Diabetic Ketoacidosis
- Hyperparathyroidism
- References
- Chapter 23 Graves' Hyperthyroidism in Pregnancy
- Chapter Outline
- Abstract
- Background
- Pathophysiology and Natural History of Graves' Hyperthyroidism During Pregnancy
- Clinical Presentation of Graves' Hyperthyroidism in Pregnancy
- Etiology of Hyperthyroidism in Pregnancy
- Laboratory Measurements and Considerations in Pregnancy
- Management and Treatment Options
- Complications of Graves' Hyperthyroidism in Pregnancy
- Postpartum Considerations
- Prevention—Preconception Counseling
- Summary
- References
- Part 9 Immunotherapy–Associated Endocrinopathies
- Chapter 24 Endocrinopathies Associated With Immune Checkpoint Inhibitors
- Chapter Outline
- Abstract
- Mechanism of Action of Anti-cytotoxic T-Lymphocyte Antigen 4 and Anti-programmed Death 1/or Its Ligand for Cancer Therapy
- Specific Endocrinopathies Associated With Immune Checkpoint Inhibitor Therapy
- Combination Therapy
- Endocrinopathies and Treatment Response
- Diagnosis and Management
- Conclusions
- References
- Part 10 Endocrine Responses in Critically Ill Trauma Patients: Nuclear Emergency
- Chapter 25 Endocrine Responses in Critically Ill and Trauma Patients
- Chapter Outline
- Abstract
- Introduction
- Normal Response to Stress
- Regulation of the HPA Axis
- Glucocorticoids in Acute Critical Illness
- Glucocorticoids in Chronic Critical Illness
- Inappropriate or Inadequate Response to Stress
- Summary
- References
- Chapter 26 Use of Potassium Iodide in a Nuclear Emergency
- Chapter Outline
- Abstract
- Preamble
- How Does Potassium Iodide Protect the Thyroid?
- What Are the Sources of Exposure to Radioactive Iodine?
- What Are the Risks of Exposure to Radioactive Iodine?
- Availability of Potassium Iodide in the United States
- Guidelines for Use
- Safety and Possible Side Effects of Potassium Iodide
- Additional Measures to Protect the Thyroid
- The Aftermath
- References
- Index
- Edition: 1
- Published: May 13, 2021
- Imprint: Elsevier
- No. of pages: 368
- Language: English
- Hardback ISBN: 9780323760973
- eBook ISBN: 9780323760980
- eBook ISBN: 9780323760997
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