Early and Late Presentation of Physical Changes of Puberty: Precocious and Delayed Puberty Revisited, An Issue of Endocrinology and Metabolism Clinics of North America

1st Edition, Volume 53-2 - April 30, 2024
Editors: Peter A. Lee, John S. Fuqua
Language: English
Hardback ISBN:
9 7 8 - 0 - 4 4 3 - 1 2 9 2 9 - 2
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 1 2 9 3 0 - 8

In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Peter A. Lee and John S. Fuqua bring their considerable expertise to the topic of Precoc… Read more

Early and Late Presentation of Physical Changes of Puberty: Precocious and Delayed Puberty Revisited, An Issue of Endocrinology and Metabolism Clinics of North America

Purchase options

Info / Buy

Limited Offer

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code needed.

Institutional subscription on ScienceDirect

Request a sales quote

In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Peter A. Lee and John S. Fuqua bring their considerable expertise to the topic of Precocious and Delayed Puberty Revisited. Top experts provide practical discussions of physical evidence of early or late pubertal development, offering a reasonable approach to patients presenting with these chief complaints.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
Normal Puberty
Key points
Introduction
Gonadarche
Pubarche and adrenarche
Secondary sex characteristics associated with puberty
Ontogeny of gonadotropin-releasing hormone neurons
Minipuberty
Gonadarche and gonads
Feedback at the hypothalamus and pituitary
Genetics of puberty
Secular trends toward earlier puberty
Summary
Clinics care points
Females with Breast Development before Three Years of Age
Key points
Introduction
Definition and clinical presentation
Etiology
Current evidence
Suggested clinical approach and counseling
Clinics care points
Premature Pubarche: A Pragmatic Approach
Key points
Introduction
Defining premature pubarche and premature adrenarche
Clinical presentation
Natural history
Laboratory findings
Benign genital hair of infancy: a variant of premature pubarche?
Controversies about missed diagnoses
Is a bone age needed in premature pubarche?
Summary/recommendations
Clinics care points
Isolated Vaginal Bleeding Before the Onset of Puberty
Key points
Introduction
Background
Etiology
Differential diagnosis
Evaluation
Discussion
Summary
Clinics care points
Diagnosis of Central Precocious Puberty
Key points
Timing of puberty
Clinical evaluation
Laboratory evaluation
Imaging studies
Summary
Clinics care points
Treatment of Central Precocious Puberty with a Focus on Girls
Key points
Gonadotropin-releasing hormone analogs
Future directions
Clinics care points
Diagnosis, Treatment, and Outcomes of Males with Central Precocious Puberty
Key points
Introduction
Incidence and secular trends
Underlying causes
Clinical evaluation and diagnosis
Treatment
Outcomes of treated and untreated central precocious puberty in males
Summary
Clinics care points
Presentation and Care for Children with Peripheral Precocious Puberty
Key points
Introduction
Distinguishing peripheral precocious puberty from central precocious puberty
Summary
Clinics care points
Delayed Puberty Including Constitutional Delay: Differential and Outcome
Key points
Defining delayed puberty
Causes of delayed puberty
Clinical approach to the diagnostic workup of the youth with delayed puberty
Management and outcome of youth with constitutional delay of growth and puberty
Summary
Clinics care points
Hypogonadotropic Hypogonadism
Key points
Introduction
Ontogeny of GnRH neurons
Components of the HPG axis
Classification of hypogonadotropic hypogonadism
Congenital hypogonadotropic hypogonadism
Pituitary hormone deficiency
Acquired hypogonadism
Functional
Diagnosis of hypogonadotropic hypogonadism
Treatment of hypogonadotropic hypogonadism in males
Treatment of hypogonadotropic hypogonadism in females
Summary
Clinics care points
Primary Amenorrhea and Premature Ovarian Insufficiency
Key points
Introduction
Definitions
Background
Turner syndrome and X chromosome monosomy
Differences in sex development
Müllerian agenesis
Other causes of premature ovarian insufficiency
Clinical evaluation
Treatment
Bone health
Gonad status, fertility potential, and fertility preservation
Behavioral health and sexuality
Transition to adult health care
Summary
Clinics care points
Hormone Therapy During Infancy or Early Childhood for Patients with Hypogonadotropic Hypogonadism, Klinefelter or Turner Syndrome: Has the Time Come?
Key points
Introduction
Summary
Clinics care points

Life sciences

Physical sciences & Engineering

Social sciences & Humanities

Health

Early and Late Presentation of Physical Changes of Puberty: Precocious and Delayed Puberty Revisited, An Issue of Endocrinology and Metabolism Clinics of North America

Purchase options

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code needed.

Institutional subscription on ScienceDirect

Peter A. Lee