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Elsevier

Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers

  • 1st Edition - October 22, 2025
  • Latest edition
  • Editors: Rajendra Awasthi, Santosh Kumar Singh, Anurag Kumar Singh
  • Language: English

Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers delivers an up-to-date and complete overview of the range of biomedical applications for porous… Read more

Description

Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers delivers an up-to-date and complete overview of the range of biomedical applications for porous silicon nanomaterials, with a special emphasis on drug delivery. This book introduces the fundamentals and beneficial properties of porous silicon, including thermal properties and stabilization, photochemical and nonthermal chemical modification, protein modification, and biocompatibility. The book then builds on the systematic detailing of each biomedical application using porous silicon, such as vaccine development, drug delivery, and tissue engineering. It also contains new insights on in-vivo assessment of porous silicon, photodynamic and photothermal therapy, micro- and nanoneedles, cancer immunotherapy, and more. Drug Delivery and Biomedical Applications of Porous Silicon-Based Nanocarriers is of interest to researchers in the fields of materials science, nanotechnology, pharmaceutical science, biomedical engineering, and cancer research.

Key features

  • Details synthesis approaches and methodologies for porous silicon-based nanocarriers, enabling structural understanding and therapeutic applications
  • Highlights the role of silica nanoparticles in targeted drug delivery, emphasizing their impact on cancer therapy, immunotherapy, neurodegenerative disorders, and other biomedical applications
  • Explores clinical aspects and trials of silica nanoparticles for treatment options

Readership

Researchers and postgraduate students in the fields of materials science, nanotechnology, pharmaceutical science, and biomedical engineering, with an interest the development of novel materials

Table of contents

1. Historical advancements in targeted nanoscale drug delivery systems

2. Synthesis of Porous Silicon-based Nanoparticles

3. Characterization techniques for mesoporous silicon nanoparticles

4. Mesoporous silicon for solubility enhancement of drugs

5. Porous silicon-based nanocarriers for tumor targeting

6. Porous silicon and related composites for topical drug delivery

7. Porous silicon nanocarriers for the management of neurodegenerative disorders

8. Functionalized silica nanocarriers for brain targeted delivery

9. Porous silicon-based materials in nanoneedle and microneedle-based drug delivery systems

10. Porous silicon-based drug delivery carriers in cancer management

11. Stimuli-responsive silica nanoparticles: Smart systems for controlled drug delivery

12. Mesoporous silica-based nanocarriers in pulmonary drug delivery

13. Porous silicon nanoparticles for improved cellular uptake and targeted drug delivery

14. Recent advances in porous silicon-based technology for biomedical applications

15. Immunotherapeutic applications of porous silicon nanoparticles

16. Bioengineered porous silicon nanoparticles in vaccine development

17. Bioavailability enhancement of poorly soluble drugs with mesoporous silicon

18. Silica nanoparticles in clinical trials

19. Mesoporous silica nanoparticles for therapeutic uses: from bench to clinics

20. Future perspectives of mesoporous silica-based nanocarriers in drug delivery

Product details

  • Edition: 1
  • Latest edition
  • Published: October 22, 2025
  • Language: English

About the editors

RA

Rajendra Awasthi

Rajendra Awasthi is Professor of Pharmaceutics at Department of Pharmaceutical Sciences, School of Health Sciences & Technology, University of Petroleum and Energy Studies, UPES, Dehradun, India.

Affiliations and expertise
Professor, Department of Pharmaceutical Sciences, School of Health Sciences & Technology, University of Petroleum and Energy Studies, UPES, Dehradun, India

SS

Santosh Kumar Singh

Santosh Kumar Singh is a Senior Scientist at the Centre of Experimental Medicine & Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.

Affiliations and expertise
Senior Scientist, Centre of Experimental Medicine and Surgery (CEMS), Faculty of Medicine, Institute of Medical Sciences, Banaras Hindu University, India

AS

Anurag Kumar Singh

Dr. Anurag Kumar Singh is a Research Associate (ICMR-RA) in the Department of Pharmaceutical Engineering and Technology at IIT BHU, Varanasi. He earned his PhD from the Centre of Experimental Medicine and Surgery, IMS, BHU, and an M. Pharm from Central University of Rajasthan. With more than 3.5 years of postdoctoral experience, he has worked at Alabama State University (Cancer Biology Research and Training) and Bar-Ilan University (Institute of Nanotechnology & Advanced Materials, Israel). His research centers on nano-particulate systems for chronic pain, neurodegenerative disorders, and brain-targeted drug delivery, including dendrimers, nanoporous silica/silicon materials, and polymeric nanoparticles for controlled delivery. He aims to develop nanomedicines for biomedical applications and to bridge engineering, pharmaceutical, and medical research. He has published widely, including reviews/editorials, and authored/editor of four books and over ten book chapters.
Affiliations and expertise
Research Associate, Department of Pharmaceutical Engineering and Technology, Indian Institute of Technology (Banaras Hindu University), Varanasi, India

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