Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases
- 1st Edition - April 12, 2019
- Latest edition
- Editor: Goutam Brahmachari
- Language: English
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting… Read more
Description
Description
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more.
In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases.
Key features
Key features
- Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery
- Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases
- Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases
Readership
Readership
Natural products chemists, Synthetic chemists, Phytochemists, Medicinal chemists, Neglected disease researchers, Combinatorial chemists, Pharmaceutical Scientists, Plant Scientists, Manufacturers of natural products, Researchers in both academia and industry
Table of contents
Table of contents
1. Therapeutics from Natural Products against Neglected Tropical Diseases: An Overview
2. Marine Natural Products as Strategic Prototypes in the Development of a New Generation of Antimalarial Agents
3. Sesquiterpene Lactones: A Versatile Class of Structurally Diverse Natural Products and Their Semisynthetic Analogs as Potential Antimalarials
4. Natural and Synthetic Quinoline Molecules against Tropical Parasitic Pathologies: An Analysis of Activity and Structural Evolution for Developing New Quinoline-based Antiprotozoal Agents
5. Promising Trypanocidal Heterocyclic Compounds of Natural Origin and Their Synthetic Analogs
6. Oxidative Stress in Schistosomiasis, Echinococcosis, and Trypanosomiasis: A Therapeutic Approach
7. Plant Derived Compounds against Protozoan Neglected Diseases: Towards Sustainable Drug Development
8. Leishmaniasis Control: Limitations of Current Drugs and Prospects of Natural Products
9. Natural Antileprotic Agents: A Boon for the Management of Leprosy
10. Aloe Vera: A Promising Hope Against Buruli Ulcer
11. Plant and Marine Products: A Promising Hope in Search of Therapeutics Against Dengue
12. Total Synthetic Approaches for Lucidone - A Promising Natural Lead Candidate Against Dengue Infection
Product details
Product details
- Edition: 1
- Latest edition
- Published: April 15, 2019
- Language: English
About the editor
About the editor
GB
Goutam Brahmachari
Dr. Goutam Brahmachari is a full professor of organic chemistry at Visva-Bharati University, Santiniketan, India. His research focuses on developing practical synthetic methods for carbon–carbon and carbon–heteroatom bonds using C–H functionalization, cascade, and cross-coupling techniques, with applications in medicinal heterocyclic scaffolds. He has also studied the chemistry and biology of traditionally used Indian medicinal plants, identifying novel phytochemicals of interest.
He is the founding Series Editor of Elsevier’s Natural Product Drug Discovery book series and an elected fellow of the Royal Society of Chemistry. His awards include the Acharya P. C. Ray Memorial Lecture Award (2025) from the Indian Science News Association (ISNA), Kolkata, India; the Dr. Satyajit Chakraborti Memorial Award (2025) from IEM, Kolkata, India; the Chemical Research Society of India Bronze Medal (2021); the Dr. Basudev Banerjee Memorial Award (2021) from the Indian Chemical Society; the Indian National Science Academy Teachers Award (2019); the Dr. Kalam Best Teaching Faculty Award (2017); and the Academic Brilliance Award (2015).