Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases
- 1st Edition - April 12, 2019
- Editor: Goutam Brahmachari
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 1 5 7 2 3 - 7
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 5 7 2 4 - 4
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting… Read more
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Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more.
In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases.
- Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery
- Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases
- Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases
Natural products chemists, Synthetic chemists, Phytochemists, Medicinal chemists, Neglected disease researchers, Combinatorial chemists, Pharmaceutical Scientists, Plant Scientists, Manufacturers of natural products, Researchers in both academia and industry
1. Therapeutics from Natural Products against Neglected Tropical Diseases: An Overview
2. Marine Natural Products as Strategic Prototypes in the Development of a New Generation of Antimalarial Agents
3. Sesquiterpene Lactones: A Versatile Class of Structurally Diverse Natural Products and Their Semisynthetic Analogs as Potential Antimalarials
4. Natural and Synthetic Quinoline Molecules against Tropical Parasitic Pathologies: An Analysis of Activity and Structural Evolution for Developing New Quinoline-based Antiprotozoal Agents
5. Promising Trypanocidal Heterocyclic Compounds of Natural Origin and Their Synthetic Analogs
6. Oxidative Stress in Schistosomiasis, Echinococcosis, and Trypanosomiasis: A Therapeutic Approach
7. Plant Derived Compounds against Protozoan Neglected Diseases: Towards Sustainable Drug Development
8. Leishmaniasis Control: Limitations of Current Drugs and Prospects of Natural Products
9. Natural Antileprotic Agents: A Boon for the Management of Leprosy
10. Aloe Vera: A Promising Hope Against Buruli Ulcer
11. Plant and Marine Products: A Promising Hope in Search of Therapeutics Against Dengue
12. Total Synthetic Approaches for Lucidone - A Promising Natural Lead Candidate Against Dengue Infection
- Edition: 1
- Published: April 12, 2019
- Language: English
GB
Goutam Brahmachari
Born on April 14, 1969 in Barala, a village in the district of Murshidabad (West Bengal, India), Goutam Brahmachari had his early education in his native place. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher Secondary Education (WBCHSE). Then, he moved to Visva-Bharati (a Central University founded by Rabindranath Tagore at Santiniketan, West Bengal, India) to study chemistry at the undergraduate level. After graduating from this university in 1990, he completed his master’s in 1992, specializing in organic chemistry. After receiving his Ph.D. 1997 in chemistry from the same university, he joined his alma mater the next year and has been a full professor of chemistry since 2011. The research interests of Prof. Brahmachari’s group include synthetic organic chemistry, green chemistry, natural products chemistry, and the medicinal chemistry of natural and natural product-inspired synthetic molecules. With more than 25 years of experience in teaching and research, he has produced over 260 scientific publications, including original research papers, review articles, books, and invited book chapters in the field of natural products and green chemistry. He has already authored/edited 27 books published by internationally reputed major publishing houses, namely, Elsevier Science (The Netherlands), Academic Press (Oxford), Wiley-VCH (Germany), Alpha Science International (Oxford), De Gruyter (Germany), World Scientific (Singapore), CRC Press (Taylor & Francis Group, USA), Royal Society of Chemistry (Cambridge), etc. Prof. Brahmachari serves several scientific bodies in India and abroad, and also many international journals as an editorial member. He has also been serving as co-editor-in-chief for Current Green Chemistry. Prof. Brahmachari is the founder series editor of the Elsevier Book Series ‘Natural Product Drug Discovery’. Prof. Brahmachari is an elected fellow of the Royal Society of Chemistry and a recipient of the CRSI (Chemical Research Society of India) Bronze Medal-2021 (for his contribution to research in chemistry), Dr Basudev Banerjee Memorial Award-2021 (for his contribution to the field of chemical sciences) from the Indian Chemical Society, INSA (Indian National Science Academy) Teachers Award-2019, Dr Kalam Best Teaching Faculty Award-2017, and Academic Brilliance Award, 2015 (Excellence in Research). Prof. Brahmachari was featured in the World Ranking of the Top 2% Scientists (Organic Chemistry Category) in 2020-23, the AD Scientific World Ranking of Scientists in 2022-2024, and as the Scholar GPS Highly Ranked Scholar-2024 (Lifetime, securing a position in the top 0.05% of all scholars worldwide).
Affiliations and expertise
Goutam Brahmachari, PhDFull Professor, Organic Chemistry, Department of Chemistry, Visva-Bharati (a Central University), Santiniketan, West Bengal, IndiaRead Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases on ScienceDirect