Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases
- 1st Edition - April 12, 2019
- Latest edition
- Editor: Goutam Brahmachari
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 1 5 7 2 3 - 7
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 1 5 7 2 4 - 4
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting… Read more
Discovery and Development of Therapeutics from Natural Products against Neglected Tropical Diseases draws together research on medicinal agents from natural sources as starting points for the design of drugs against Neglected Tropical Diseases (NTDs). From the prediction of promising leads and identification of active agents, to the extraction of complex molecules, the book explores novel, economical and efficacious therapeutics for these diseases. It describes current research and the role of natural products, antimalarial compounds from marine natural products and sesquiterpene lactones, natural antileprotic agents, natural products with potential against Leishmaniasis, Trypanosomiasis and Dengue, and more.
In addition, Quinoline and Isoquinoline alkaloids for developing new antiprotozoal agents are discussed, alongside anti-trypanosomatid heterocyclic compounds as structures for development. Combining the expertise of specialists from around the world, this volume aims to support and encourage researchers in the investigation of natural sources as starting points for the development of novel, safe and effective agents for use against neglected tropical diseases.
- Includes chapters written by active researchers and leading global experts deeply engaged in the research field of natural product chemistry for drug discovery
- Draws together cutting-edge research advances in natural product chemistry that are targeted at neglected tropical diseases
- Highlights the future potential of natural products as sources of novel medicinal compounds against neglected tropical diseases
Natural products chemists, Synthetic chemists, Phytochemists, Medicinal chemists, Neglected disease researchers, Combinatorial chemists, Pharmaceutical Scientists, Plant Scientists, Manufacturers of natural products, Researchers in both academia and industry
1. Therapeutics from Natural Products against Neglected Tropical Diseases: An Overview
2. Marine Natural Products as Strategic Prototypes in the Development of a New Generation of Antimalarial Agents
3. Sesquiterpene Lactones: A Versatile Class of Structurally Diverse Natural Products and Their Semisynthetic Analogs as Potential Antimalarials
4. Natural and Synthetic Quinoline Molecules against Tropical Parasitic Pathologies: An Analysis of Activity and Structural Evolution for Developing New Quinoline-based Antiprotozoal Agents
5. Promising Trypanocidal Heterocyclic Compounds of Natural Origin and Their Synthetic Analogs
6. Oxidative Stress in Schistosomiasis, Echinococcosis, and Trypanosomiasis: A Therapeutic Approach
7. Plant Derived Compounds against Protozoan Neglected Diseases: Towards Sustainable Drug Development
8. Leishmaniasis Control: Limitations of Current Drugs and Prospects of Natural Products
9. Natural Antileprotic Agents: A Boon for the Management of Leprosy
10. Aloe Vera: A Promising Hope Against Buruli Ulcer
11. Plant and Marine Products: A Promising Hope in Search of Therapeutics Against Dengue
12. Total Synthetic Approaches for Lucidone - A Promising Natural Lead Candidate Against Dengue Infection
- Edition: 1
- Latest edition
- Published: April 12, 2019
- Language: English
GB
Goutam Brahmachari
Goutam Brahmachari is a Professor of Chemistry at Visva-Bharati University, India, with over 25 years of teaching and research experience. He specializes in synthetic organic chemistry, green chemistry, natural products chemistry, and medicinal chemistry of natural and synthetic molecules. Prof. Brahmachari has authored or edited 27 books with leading international publishers and serves as co-editor-in-chief of Current Green Chemistry, as well as being the founding series editor of Elsevier’s Natural Product Drug Discovery series. An elected Fellow of the Royal Society of Chemistry, he has received prestigious awards such as the CRSI Bronze Medal (2021) and the INSA Teachers Award (2019).
Affiliations and expertise
Goutam Brahmachari, PhDFull Professor, Organic Chemistry, Department of Chemistry, Visva-Bharati (a Central University), Santiniketan, West Bengal, IndiaRead Discovery and Development of Therapeutics from Natural Products Against Neglected Tropical Diseases on ScienceDirect