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Diagnostic Pathology: Head and Neck

  • 3rd Edition - April 27, 2022
  • Latest edition
  • Authors: Lester D.R. Thompson, Susan Müller, Brenda L. Nelson
  • Language: English

**Selected for Doody’s Core Titles® 2024 in Surgical Pathology**This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitione… Read more

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Description

**Selected for Doody’s Core Titles® 2024 in Surgical Pathology**

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all areas of head and neck pathology, it incorporates the most recent clinical, pathologic, and molecular knowledge in this challenging field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Head and Neck is a one-stop reference for accurate, complete pathology reports—ideal as a day-to-day reference or as a reliable teaching resource.

Key features

  • Provides a clear framework for a better understanding of the clinical and histopathologic appearances of more than 325 new or evolving entities of the head and neck and endocrine organs
  • Features updates on recent changes in the field and current information from the AJCC Cancer Staging Manual, 8th Edition, and the World Health Organization Classification of Head and Neck Tumours, 5th Edition
  • Covers numerous new diagnostic entities, including intraductal carcinoma, sclerosing polycystic adenoma, microsecretory adenocarcinoma, adamantinoma-like Ewing sarcoma, SMARCB1- and SMARCA4-deficient carcinomas, and HPV-related multiphenotypic sinonasal carcinoma
  • Contains major updates on sinonasal tract, salivary gland, and odontogenic tumors; oropharyngeal squamous cell carcinoma and its correct classification and staging; the recent significant reclassification of neuroendocrine tumors; and changes in terminology and identification for head and neck soft tissue tumors
  • Suggests supporting studies in a realistic clinical context, with tables and immunohistochemical charts that assist with management decisions and prognostic outcome predictions
  • Features more than 3,200 images, including full-color drawings of head and neck anatomy, development pathway drawings, staging protocol illustrations, and genetic pathway graphics; radiologic images, clinical photographs, and gross images; and histology, histochemistry, immunohistochemistry, in situ hybridization, and molecular images; as well as more than 2,600 additional online-only images
  • Employs consistently templated chapters, bulleted content, key facts, and annotated images for quick, expert reference at the point of care
  • Includes the enhanced eBook version, which allows you to search all text, figures, and references on a variety of devices

Readership

Pathologists (including oral pathologists) at all levels of training: practicing, fellows, and residents

Table of contents

SECTION 1: NASAL CAVITY ANDPARANASAL SINUSES

4 Nose and Paranasal Sinuses
Lester D. R. Thompson, MD and Jonathan B. McHugh, MD
CONGENITAL/GENETIC/HEREDITARY

6 Nasal Neuroglial Heterotopia
Lester D. R. Thompson, MD

8 Nasal Dermoid Cyst and Sinus
INFECTIOUS

10 Allergic Fungal Sinusitis

14 Invasive Fungal Rhinosinusitis

16 Mycetoma

17 Rhinoscleroma

18 Rhinosporidiosis

20 Mycobacterium lepraeInfection
INFLAMMATORY-IMMUNE DYSFUNCTION

22 Chronic Rhinosinusitis
Brenda L. Nelson, DDS, MS

26 Granulomatosis With Polyangiitis
Susan Müller, DMD, MS

32 Eosinophilic Angiocentric Fibrosis
REACTIVE AND HAMARTOMAS

36 Sinonasal Inflammatory Polyp Brenda L. Nelson, DDS, MS and Lester D. R. Thompson, MD

40 Antrochoanal Polyp
Lester D. R. Thompson, MD and Brenda L. Nelson, DDS, MS

42 Mucocele of Paranasal Sinus

44 Sinonasal Hamartoma
Brenda L. Nelson, DDS, MS and Lester D. R. Thompson, MD

50 Nasal Chondromesenchymal Hamartoma

52 Extranodal Sinus Histiocytosis With Massive Lymphadenopathy

56 Myospherulosis
BENIGN NEOPLASM

58 Sinonasal Papilloma

66 Pleomorphic Adenoma, Sinonasal Tract

68 Meningioma, Sinonasal Tract

72 Ameloblastoma, Sinonasal Tract

74 Ectopic Pituitary Neuroendocrine Tumor

80 Lobular Capillary Hemangioma (Pyogenic Granuloma)

84 Sinonasal Tract Angiofibroma

88 Schwannoma/Neurofibroma, Sinonasal Tract

92 Leiomyoma and Smooth Muscle Tumors of Uncertain Malignant Potential

96 Fibromatosis/Desmoid-Type Fibromatosis

98 Solitary Fibrous Tumor, Sinonasal Tract
BORDERLINE NEOPLASM

102 Glomangiopericytoma
MALIGNANT NEOPLASM

106 Squamous Cell Carcinoma, Sinonasal Tract

114 NUT Carcinoma

116 SWI/SNF Complex-Deficient Sinonasal Carcinomas

120 Lymphoepithelial Carcinoma, Sinonasal Tract

122 Sinonasal Undifferentiated Carcinoma

128 Teratocarcinosarcoma

134 HPV-Related Multiphenotypic Sinonasal Carcinoma

138 Sinonasal Adenocarcinoma, Intestinal Type

144 Sinonasal Nonintestinal-Nonsalivary Adenocarcinoma

152 Sinonasal Renal Cell-Like Adenocarcinoma

154 Olfactory Neuroblastoma

164 Sinonasal Neuroendocrine Carcinoma

170 Mucosal Melanoma, Sinonasal Tract

176 Alveolar Rhabdomyosarcoma, Sinonasal Tract

182 Ewing Sarcoma, Including Sinonasal Adamantinoma-Like

188 Biphenotypic Sinonasal Sarcoma

192 Leiomyosarcoma, Sinonasal Tract

198 Malignant Peripheral Nerve Sheath Tumor, Sinonasal Tract

202 Fibrosarcoma, Sinonasal Tract

206 Angiosarcoma, Sinonasal Tract

210 Mesenchymal Chondrosarcoma, Sinonasal Tract

212 Undifferentiated Pleomorphic Sarcoma, Sinonasal Tract

216 Extranodal NK-/T-Cell Lymphoma, Nasal Type
Aaron Auerbach, MD, MPH

222 Metastatic/Secondary Tumors, Sinonasal Tract
SPECIMEN EXAMINATION, NASAL CAVITY & PARANASAL SINUSES

224 Specimen Examination and Staging Tools, Oropharynx

228 Specimen Examination and Staging Tools, Nasopharynx
SECTION 2: PHARYNX (NASAL, HYPO-)

234 Pharynx

236 Tornwaldt Cyst

237 Rathke Cleft Cyst

238 Dermoid

240 Low-Grade Nasopharyngeal Papillary Adenocarcinoma

244 Nasopharyngeal Carcinoma, Nonkeratinizing Types
Susan Müller, DMD, MS and Lester D. R. Thompson, MD

254 Nasopharyngeal Carcinoma, Keratinizing Type

256 Nasopharyngeal Carcinoma, Basaloid Squamous Cell Carcinoma

260 Diffuse Large B-Cell Lymphoma NOS
SECTION 3: LARYNX AND TRACHEA

266 Larynx

268 Laryngocele and Laryngeal Cysts

270 Tracheopathia Osteoplastica

272 Laryngitis: Viral, Bacterial, Fungal
REACTIVE

276 Vocal Cord Nodules and Polyps

280 Reactive Epithelial Changes

284 Contact Ulcer

286 Amyloid (Amyloidoma)

288 Squamous Papilloma

292 Granular Cell Tumor, Larynx

294 Adult Rhabdomyoma

296 Inflammatory Myofibroblastic Tumor

300 Paraganglioma, Larynx

302 Chondroma

304 EBV-Associated Smooth Muscle Tumor

306 Keratinizing Dysplasia and Carcinoma In Situ

314 Conventional Squamous Cell Carcinoma

322 Verrucous Carcinoma

326 Spindle Cell Squamous Cell Carcinoma

332 Papillary Squamous Cell Carcinoma
Lester D. R. Thompson, MD and Susan Müller, DMD, MS

336 Basaloid Squamous Cell Carcinoma

340 Adenosquamous Carcinoma

344 Neuroendocrine Neoplasms, Larynx

354 Chondrosarcoma

358 Metastatic/Secondary Tumors, Larynx and Trachea
SPECIMEN EXAMINATION, LARYNX

360 Specimen Examination and Staging Tools, Larynx and Trachea
SECTION 4: ORAL CAVITY

364 Tongue

366 Oral Mucosae
CONGENITAL/GENETIC/HEREDITARY

368 Ectopic (Lingual) Thyroid

370 White Sponge Nevus

372 Multifocal Epithelial Hyperplasia (Heck Disease)

374 Oral Hairy Leukoplakia

376 Oral Infections

380 Oral Syphilis

384 Aphthous Stomatitis

390 Pemphigus Vulgaris

392 Mucous Membrane Pemphigoid

394 Oral Lichen Planus

398 Erythema Multiforme

400 Lupus Erythematosus

404 Frictional Hyperkeratosis

405 Pseudoepitheliomatous Hyperplasia

406 Necrotizing Sialometaplasia

408 Traumatic Ulcerative Granuloma With Stromal Eosinophilia

410 Giant Cell Fibroma

411 Amalgam Tattoo

412 Tobacco Changes

414 Parulis
NONNEOPLASTIC LESIONS

415 Fordyce Granules

416 Mucocele and Ranula

418 Verruciform Xanthoma

419 Hairy Tongue

420 Geographic Tongue

422 Juxtaoral Organ of Chievitz

423 Heterotopic Salivary Glands

424 Squamous Papilloma (Including Verruca and Condyloma)

428 Fibroma, Oral Cavity

430 Pyogenic Granuloma

432 Peripheral Giant Cell Granuloma

434 Peripheral Ossifying Fibroma

436 Mucosal Neuroma

438 Solitary Circumscribed Neuroma

440 Acquired Melanocytic Nevus

444 Melanoacanthoma

445 Oral Lymphangioma

446 Teratoma, Oral Cavity

448 Congenital Granular Cell Epulis

450 Granular Cell Tumor, Oral Cavity

454 Melanotic Neuroectodermal Tumor of Infancy

456 Ectomesenchymal Chondromyxoid Tumor

460 GLI1-Altered Soft Tissue Tumor

462 Dysplasia and Carcinoma In Situ

468 Proliferative Verrucous Leukoplakia

470 Squamous Cell Carcinoma, Oral Cavity

476 Mucosal Melanoma, Oral Cavity

480 Extraskeletal Myxoid Chondrosarcoma

482 Angiosarcoma, Oral Cavity

484 Kaposi Sarcoma, Oral Cavity

486 Metastatic/Secondary Tumors: Oral Cavity; Jaw
SPECIMEN EXAMINATION, LIP AND ORAL CAVITY

488 Specimen Examination and Staging Tools, Lip and Oral Cavity
SECTION 5: OROPHARYNX

492 Infectious Mononucleosis

496 HIV Infection of Tonsils and Adenoids

500 Lymphangiomatous Polyp

502 Oropharyngeal Carcinoma
SECTION 6: SALIVARY GLANDS

508 Major Salivary Glands

510 HIV Salivary Gland Disease

512 Benign Lymphoepithelial Cyst

514 Benign Lymphoepithelial Lesion

516 Sjögren Syndrome Brenda L. Nelson, DDS, MS and Lester D. R. Thompson, MD

520 IgG4-Related Salivary Gland Disease

524 Oncocytosis (Oncocytic Hyperplasia)

525 Sialolithiasis

526 Pleomorphic Adenoma

536 Basal Cell Adenoma

540 Myoepithelioma

544 Warthin Tumor (Papillary Cystadenoma Lymphomatosum)

548 Oncocytoma

554 Canalicular Adenoma

556 Cystadenoma

558 Ductal Papillomas

562 Salivary Gland Adenoma: Lymphadenoma, Sebaceous Lymphadenoma, and Sebaceous Adenoma

564 Sclerosing Polycystic Adenoma

566 Keratocystoma

567 Sialolipoma

568 Hemangioma, Parotid Gland

570 Sialoblastoma

574 Mucoepidermoid Carcinoma, Salivary

584 Adenoid Cystic Carcinoma

592 Acinic Cell Carcinoma

600 Secretory Carcinoma, Salivary Gland

604 Microsecretory Adenocarcinoma

606 Polymorphous Adenocarcinoma, Low-Grade Subtype

612 Polymorphous Adenocarcinoma, Cribriform Subtype

614 Hyalinizing Clear Cell Carcinoma

620 Basal Cell Adenocarcinoma

624 Intraductal Carcinoma

626 Salivary Duct Carcinoma

636 Myoepithelial Carcinoma

640 Epithelial-Myoepithelial Carcinoma

646 Carcinoma Ex-Pleomorphic Adenoma

656 Mucinous Adenocarcinoma

660 Sclerosing Microcystic Adenocarcinoma

662 Lymphoepithelial Carcinoma, Salivary Gland

668 Sebaceous Carcinoma and Sebaceous Lymphadenocarcinoma

670 Adenocarcinoma, Not Otherwise Specified

672 Small Cell Neuroendocrine Carcinoma, Salivary Gland

676 Lymphoma, Salivary Gland

678 Metastatic/Secondary Tumors, Salivary Glands
SPECIMEN EXAMINATION, SALIVARY GLANDS

680 Specimen Examination and Staging Tools, Salivary Glands
SECTION 7: JAW

684 Teeth

686 Cherubism
REACTIVE/INFECTIOUS

688 Tori

690 Osteomyelitis

694 Osteonecrosis

698 Cemento-Osseous Dysplasia

700 Fibrous Dysplasia

704 Paget Disease of Bone
CYSTS

708 Simple Bone Cyst

710 Pseudocysts and Surgical Ciliated Cysts of Jaw

712 Periapical Cyst/Granuloma

714 Nasopalatine Duct Cyst

716 Dentigerous Cyst

720 Orthokeratinized Odontogenic Cyst

722 Lateral Periodontal Cyst

724 Calcifying Odontogenic Cyst

726 Glandular Odontogenic Cyst

728 Odontogenic Keratocyst

732 Adenomatoid Odontogenic Tumor

734 Squamous Odontogenic Tumor

736 Calcifying Epithelial Odontogenic Tumor

738 Ameloblastoma, Jaw

744 Odontoma (Complex and Compound)

746 Ameloblastic Fibroma/Fibroodontoma

748 Odontogenic Fibroma

750 Cementoblastoma

752 Odontogenic Myxoma

754 Central Giant Cell Granuloma

756 Ossifying Fibroma, Jaw

760 Juvenile Active Ossifying Fibroma

764 Osteoma

766 Osteoblastoma

768 Ameloblastic Carcinoma

770 Clear Cell Odontogenic Carcinoma

772 Ghost Cell Odontogenic Carcinoma

774 Ameloblastic Fibrosarcoma

776 Osteosarcoma, Jaw

780 Chondrosarcoma, Jaw

786 Plasma Cell Myeloma, Jaw
SECTION 8: EAR AND TEMPORAL BONE

790 Ear

792 Accessory Tragus

794 Encephalocele

796 First Branchial Cleft Anomaly

800 Otitis Media

802 Necrotizing Otitis Externa

804 Chondrodermatitis Nodularis Chronica Helicis

806 Otic Polyp

808 Relapsing Polychondritis
DEGENERATIVE

810 Cystic Chondromalacia (Auricular Pseudocyst)

812 Otosclerosis
METABOLIC

814 Gout

816 Exostosis

818 Keloid
David Cassarino, MD, PhD and Lester D. R. Thompson, MD

820 Synovial Chondromatosis (Temporomandibular Joint)

822 Ceruminous Adenoma

826 Cholesteatoma

830 Jugulotympanic Paraganglioma

836 Vestibular Schwannoma

840 Meningioma, Ear and Temporal Bone

842 Epithelioid Hemangioma

844 Middle Ear Neuroendocrine Tumor

850 Endolymphatic Sac Tumor

854 Langerhans Cell Histiocytosis, Ear and Temporal Bone

856 Atypical Fibroxanthoma

860 Squamous Cell Carcinoma, Ear and Temporal Bone
Lester D. R. Thompson, MD and David Cassarino, MD, PhD

864 Basal Cell Carcinoma

866 Merkel Cell Carcinoma

870 Dermatofibrosarcoma Protuberans

874 Ceruminous Adenocarcinoma

878 Rhabdomyosarcoma, Ear and Temporal Bone

882 Metastatic/Secondary Tumors, Ear and Temporal Bone
SECTION 9: NECK (SOFT TISSUE ANDLYMPH NODES)

886 Lymph Nodes

888 Branchial Cleft Cyst

894 Dermoid Cyst

896 Cervical Thymic Cyst

898 Bronchogenic Cyst

900 Cat-Scratch Disease

904 Bacillary Angiomatosis

906 Mycobacterial Spindle Cell Pseudotumor

908 Sarcoidosis

910 Nodular Fasciitis

912 Lymphangioma, Neck

914 Lipoma

916 Spindle Cell Lipoma

918 Hibernoma

920 Lipoblastoma

922 Elastofibroma

924 Perineurioma

928 Fetal Rhabdomyoma

932 Nuchal-Type Fibroma

934 Branchioma (Ectopic Hamartomatous Thymoma)

936 Carotid Body Paraganglioma

942 Metastatic Cystic Squamous Cell Carcinoma

948 Synovial Sarcoma

954 Chordoma

960 Liposarcoma
SECTION 10: THYROID GLAND

966 Thyroid Gland

968 Thyroglossal Duct Cyst

972 Ectopic Thyroid Gland

974 Solid Cell Nests

976 Dyshormonogenetic Goiter

980 Infectious Thyroiditis
INFLAMMATORY-IMMUNE DYSFUNCTION

984 Palpation Thyroiditis

986 Subacute Granulomatous Thyroiditis (de Quervain)

992 Chronic Lymphocytic (Hashimoto) Thyroiditis

998 Graves Disease (Diffuse Hyperplasia)

1004 Amyloid Goiter

1008 IgG4-Related Thyroiditis

1010 Multinodular Hyperplasia

1018 Pigments and Crystals in Thyroid Gland

1020 Post Thyroid Biopsy Changes

1024 C-Cell Hyperplasia (Physiologic)

1026 Radiation Thyroiditis

1028 Follicular Adenoma

1034 Follicular Adenoma With Papillary Architecture

1038 Oncocytic Follicular Adenoma

1042 Noninvasive Follicular Thyroid Neoplasm With Papillary-Like Nuclei

1046 Hyalinizing Trabecular Tumor

1050 Thyroid Teratoma

1054 Paraganglioma, Thyroid Gland

1056 Solitary Fibrous Tumor, Thyroid Gland

1060 Leiomyoma, Thyroid Gland

1062 Schwannoma, Thyroid Gland

1064 Langerhans Cell Histiocytosis, Thyroid Gland

1068 Ovarian Thyroid Tissue

1072 Papillary Thyroid Carcinoma

1088 Follicular Thyroid Carcinoma

1100 Oncocytic Follicular Thyroid Carcinoma

1106 High-Grade Follicular-Derived Thyroid Carcinomas

1114 Undifferentiated (Anaplastic) Thyroid Carcinoma

1122 Medullary Thyroid Carcinoma

1134 Thyroblastoma

1136 Mucoepidermoid Carcinoma, Thyroid Gland

1140 Sclerosing Mucoepidermoid Carcinoma With Eosinophilia

1144 Cribriform Morular Thyroid Carcinoma

1146 Spindle Epithelial Tumor With Thymus-Like Elements

1150 Thymic Carcinoma Family Thyroid Tumors

1154 Angiosarcoma, Thyroid Gland

1158 Leiomyosarcoma, Thyroid Gland

1162 Malignant Peripheral Nerve Sheath Tumor, Thyroid Gland

1166 Follicular Dendritic Cell Sarcoma, Thyroid Gland

1170 Lymphoma, Thyroid Gland

1180 Metastatic/Secondary Tumors, Thyroid Gland
SPECIMEN EXAMINATION, THYROID GLAND

1186 Specimen Examination and Staging Tools, Thyroid Gland
SECTION 11: PARATHYROID GLANDS

1190 Parathyroid
NONNEOPLASTIC

1192 Parathyroid Hyperplasia

1200 Tertiary Hyperparathyroidism

1201 Chronic Parathyroiditis

1202 Parathyroid Adenoma

1210 Parathyroid Carcinoma

1216 Metastatic/Secondary Tumors, Parathyroid Glands

Review quotes

Doody's Core Titles® 2022

Product details

  • Edition: 3
  • Latest edition
  • Published: June 18, 2022
  • Language: English

About the authors

LT

Lester D.R. Thompson

Affiliations and expertise
Head and Neck Pathology Consultations, Woodland Hills, California, USA

SM

Susan Müller

Susan Müller, DMD, MS, is Professor Emeritus with the Department of Otolaryngology, Head and Neck Surgery, at Emory University School of Medicine in Atlanta, Georgia. Müller is also with Atlanta Oral Pathology, which specializes in the pathology of the oral cavity and the head and neck.
Affiliations and expertise
Atlanta Oral Pathology, Professor Emeritus, Department of Otolaryngology, Head and Neck Surgery, Emory University School of Medicine, Atlanta, Georgia

BN

Brenda L. Nelson

Brenda L. Nelson, DDS, MS, is a Consulting Pathologist with Scripps Oral Pathology Service in San Diego, California
Affiliations and expertise
Consulting Pathologist, Scripps Oral Pathology Service, San Diego, California