Diagnostic Pathology: Gynecological

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering the full range of nonneoplastic and neoplastic conditions of the female genital tract, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today’s practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Gynecological is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource.

Cover image
Title page
Table of Contents
Copyright
Dedications
Contributing Authors
Preface
Acknowledgments
Sections
List of Tables
SECTION 1: VULVA
INFLAMMATORY DISORDERS
Chapter 1: Lichen Planus
Chapter 2: Fixed Drug Eruption
Chapter 3: Erythema Multiforme
Chapter 4: Plasmacytosis Mucosae (Zoon)
Chapter 5: Lichen Sclerosus
Chapter 6: Allergic Contact Dermatitis
Chapter 7: Psoriasis
Chapter 8: Lichen Simplex Chronicus
Chapter 9: Foreign Body Granulomas
Chapter 10: Verruciform Xanthoma
Chapter 11: Crohn Disease
Chapter 12: Epidermolytic Acanthoma
Chapter 13: Papular Acantholytic Dermatosis
Chapter 14: Behçet Disease
Chapter 15: Pemphigus
Chapter 16: Bullous Pemphigoid
Chapter 17: Mucous Membrane Pemphigoid (Cicatricial Pemphigoid)
Chapter 18: Pemphigoid Gestationis (Herpes Gestationis)
Chapter 19: Linear IgA Disease
Chapter 20: Herpes Simplex Virus
Chapter 21: Syphilis
Chapter 22: Chancroid
Chapter 23: Molluscum Contagiosum
Chapter 24: Dermatophytosis
Chapter 25: Candidiasis
Chapter 26: Scabetic Infestations
Chapter 27: Hidradenitis Suppurativa
NONNEOPLASTIC LESIONS
Chapter 28: Bartholin Cyst
Chapter 29: Endometriosis
Chapter 30: Fibroepithelial Stromal Polyp
Chapter 31: Massive Edema
EPITHELIAL TUMORS
Chapter 32: HPV-Associated Lesions (Excluding Vulvar Intraepithelial Neoplasia)
Chapter 33: Vulvar Intraepithelial Neoplasia
Chapter 34: Squamous Cell Carcinoma
Chapter 35: Basal Cell Carcinoma
Chapter 36: Mucosal Melanotic Macule
Chapter 37: Common Melanocytic Nevus
Chapter 38: Atypical Nevus of Genital Tract
Chapter 39: Malignant Melanoma
Chapter 40: Extramammary Paget Disease
Chapter 41: Bartholin Gland Carcinoma
Chapter 42: Hidradenoma Papilliferum
Chapter 43: Fibroadenoma and Phyllodes Tumor
Chapter 44: Syringoma
Chapter 45: Mixed Tumor
Chapter 46: Microcystic Adnexal Carcinoma
Chapter 47: Eccrine Spiradenoma
Chapter 48: Trichofolliculoma
Chapter 49: Trichoepithelioma
Chapter 50: Sebaceous Hyperplasia
Chapter 51: Sebaceous Carcinoma
MESENCHYMAL TUMORS
Chapter 52: Angiomyofibroblastoma
Chapter 53: Cellular Angiofibroma
Chapter 54: Prepubertal Vulval Fibroma
Chapter 55: Superficial Angiomyxoma
Chapter 56: Deep (Aggressive) Angiomyxoma
Chapter 57: Smooth Muscle Tumors
Chapter 58: Granular Cell Tumor
Chapter 59: Dermatofibrosarcoma Protuberans
Chapter 60: Solitary Fibrous Tumor
Chapter 61: Lipoblastoma-Like Tumor
Chapter 62: Epithelioid Sarcoma
SECTION 2: VAGINA
INFLAMMATORY DISORDERS
Chapter 63: Desquamative Inflammatory Vaginitis
Chapter 64: Ligneous Vaginitis
Chapter 65: Malakoplakia
NONNEOPLASTIC LESIONS
Chapter 66: Vaginal Cysts
Chapter 67: Adenosis
Chapter 68: Polyps
Chapter 69: Fallopian Tube Prolapse
TUMORS
Chapter 70: Vaginal Intraepithelial Neoplasia
Chapter 71: Squamous Cell Carcinoma
Chapter 72: Adenocarcinomas, Nonclear Cell Type
Chapter 73: Clear Cell Carcinoma
Chapter 74: Mixed Tumor
Chapter 75: Rhabdomyoma
Chapter 76: Malignant Melanoma
Chapter 77: Yolk Sac Tumor
Chapter 78: Secondary Neoplasms
SECTION 3: UTERINE CERVIX
NONNEOPLASTIC LESIONS
Chapter 79: Cervical Infections
Chapter 80: Atrophy
Chapter 81: Transitional Cell Metaplasia
Chapter 82: Immature Squamous Metaplasia
Chapter 83: Tubal and Tuboendometrioid Metaplasia
Chapter 84: Arias-Stella Reaction
Chapter 85: Deciduosis
Chapter 86: Endometriosis
Chapter 87: Tunnel Clusters
Chapter 88: Microglandular Hyperplasia
Chapter 89: Deep Glands and Nabothian Cysts
Chapter 90: Endocervical Glandular Hyperplasia (Diffuse and Lobular)
Chapter 91: Endocervical Polyp
Chapter 92: Ectopic Prostate Tissue
Chapter 93: Mesonephric Remnants/Hyperplasia
Chapter 94: Endocervicosis
EPITHELIAL TUMORS
Chapter 95: Müllerian Papilloma
Chapter 96: Squamous Intraepithelial Lesion/Dysplasia
Chapter 97: Squamous Cell Carcinoma
Chapter 98: HPV- and Non-HPV-Associated In Situ Adenocarcinoma
Chapter 99: HPV-Associated Adenocarcinomas
Chapter 100: HPV-Associated Adenosquamous Carcinoma
Chapter 101: Gastric-Type Adenocarcinoma, HPV Independent
Chapter 102: Clear Cell Adenocarcinoma, HPV Independent
Chapter 103: Mesonephric Adenocarcinoma, HPV Independent
Chapter 104: Endometrioid Adenocarcinoma, HPV Independent
Chapter 105: Patterns of Invasion in Endocervical Adenocarcinoma (Silva Classification)
Chapter 106: Adenoid Basal Carcinoma
Chapter 107: Adenoid Cystic Carcinoma
Chapter 108: Neuroendocrine Tumors
Chapter 109: Carcinosarcoma
MIXED EPITHELIAL STROMAL TUMORS
Chapter 110: Endocervical-Type Adenomyoma
Chapter 111: Müllerian Adenosarcoma
MESENCHYMAL TUMORS
Chapter 112: Rhabdomyosarcoma
Chapter 113: Spindle Cell Sarcomas With NTRK Rearrangement
Chapter 114: Spindle Cell Sarcoma With Tyrosine Kinase Abnormalities or Spindle Cell Sarcoma, NOS
OTHERS
Chapter 115: Lymphomas and Leukemias of Lower Genital Tract
Chapter 116: Metastatic/Secondary Tumors
SECTION 4: UTERINE CORPUS
NONNEOPLASTIC LESIONS
Chapter 117: Endometritis
Chapter 118: Endometrial Metaplasias
Chapter 119: Endometrial Polyp
EPITHELIAL TUMORS
Chapter 120: Endometrial Intraepithelial Neoplasia/Atypical Endometrial Hyperplasia
Chapter 121: Endometrioid Adenocarcinoma and Variants
Chapter 122: Serous Adenocarcinoma
Chapter 123: Clear Cell Adenocarcinoma
Chapter 124: Mesonephric-Like Carcinoma
Chapter 125: Squamous Cell Carcinoma
Chapter 126: Neuroendocrine Carcinoma
Chapter 127: Undifferentiated/Dedifferentiated Carcinoma
Chapter 128: Carcinosarcoma
MIXED EPITHELIAL STROMAL TUMORS
Chapter 129: Endometrioid-Type Adenomyoma
Chapter 130: Atypical Polypoid Adenomyoma
Chapter 131: Müllerian Adenosarcoma
MESENCHYMAL TUMORS
Chapter 132: Leiomyoma and Variants
Chapter 133: Intravenous Leiomyomatosis
Chapter 134: Leiomyosarcoma
Chapter 135: Perivascular Epithelioid Cell (PEC) Proliferations
Chapter 136: Inflammatory Myofibroblastic Tumor
Chapter 137: Benign and Low-Grade Endometrial Stromal Tumors
Chapter 138: High-Grade Endometrial Stromal Sarcoma
Chapter 139: Uterine Tumors Resembling Ovarian Sex Cord Tumors
Chapter 140: Rhabdomyosarcoma
Chapter 141: Alveolar Soft Part Sarcoma
Chapter 142: SMARC-Deficient Uterine Sarcoma
Chapter 143: Undifferentiated Uterine Sarcoma
OTHERS
Chapter 144: Adenomatoid Tumor
Chapter 145: Central Primitive Neuroectodermal Tumor
Chapter 146: Wilms Tumor
Chapter 147: Germ Cell Tumors
Chapter 148: Lymphoma and Leukemia
Chapter 149: Metastatic/Secondary Tumors
SECTION 5: FALLOPIAN TUBE AND BROAD LIGAMENT
NONNEOPLASTIC LESIONS
Chapter 150: Metaplasias
Chapter 151: Pseudocarcinomatous Hyperplasia
Chapter 152: Salpingitis
Chapter 153: Endometriosis
TUMORS
Chapter 154: Metaplastic Papillary Tumor
Chapter 155: Adenomatoid Tumor
Chapter 156: Female Adnexal Tumor of Probable Wolffian Origin
Chapter 157: Serous Borderline Tumor
Chapter 158: Serous Carcinoma, Including Serous Tubal Intraepithelial Carcinoma (STIC)
Chapter 159: Endometrioid Adenocarcinoma
Chapter 160: STK11 Adnexal Tumor
SECTION 6: OVARY
NONNEOPLASTIC LESIONS
Chapter 161: Follicular Cysts
Chapter 162: Stromal Hyperplasia and Hyperthecosis
Chapter 163: Pregnancy Luteoma
Chapter 164: Hyperreactio Luteinalis
Chapter 165: Large Solitary Luteinized Follicle Cyst of Pregnancy
Chapter 166: Torsion
Chapter 167: Endometriosis and Deciduosis
Chapter 168: Massive Edema and Fibromatosis
Chapter 169: Autoimmune Oophoritis
Chapter 170: Luteinized Thecoma With Sclerosing Peritonitis
EPITHELIAL TUMORS
Chapter 171: Benign Serous Tumors
Chapter 172: Serous Borderline Tumor
Chapter 173: Low-Grade Serous Adenocarcinoma
Chapter 174: High-Grade Serous Adenocarcinoma
Chapter 175: Benign Endometrioid Tumors
Chapter 176: Endometrioid Borderline Tumor
Chapter 177: Endometrioid Adenocarcinoma
Chapter 178: Benign Mucinous Tumors
Chapter 179: Mucinous Borderline Tumor, Intestinal Type
Chapter 180: Seromucinous Borderline Tumor
Chapter 181: Mucinous Adenocarcinoma
Chapter 182: Mucinous Cystic Tumor With Mural Nodules
Chapter 183: Clear Cell Borderline Tumor
Chapter 184: Clear Cell Carcinoma
Chapter 185: Benign Brenner Tumor
Chapter 186: Borderline Brenner Tumor
Chapter 187: Malignant Brenner Tumor
Chapter 188: Small Cell Carcinoma, Hypercalcemic Type
Chapter 189: Small Cell Carcinoma, Pulmonary Type
Chapter 190: Large Cell Neuroendocrine Carcinoma
Chapter 191: Hepatoid Carcinoma
Chapter 192: Mesonephric-Like Carcinoma
Chapter 193: Carcinosarcoma
MIXED EPITHELIAL-STROMAL TUMORS
Chapter 194: Mesodermal Adenosarcoma
STROMAL AND SEX CORD TUMORS
Chapter 195: Fibromatous Neoplasms
Chapter 196: Thecoma
Chapter 197: Sclerosing Stromal Tumor
Chapter 198: Microcystic Stromal Tumor
Chapter 199: Signet-Ring Stromal Tumor
Chapter 200: Adult Granulosa Cell Tumor
Chapter 201: Juvenile Granulosa Cell Tumor
Chapter 202: Sertoli-Leydig Cell Tumor
Chapter 203: Sertoli Cell Tumor
Chapter 204: Leydig Cell Tumor
Chapter 205: Stromal Luteoma
Chapter 206: Steroid Cell Tumor, NOS
Chapter 207: Sex Cord Tumor With Annular Tubules
Chapter 208: Sex Cord-Stromal Tumor, NOS
MESENCHYMAL TUMORS
Chapter 209: Smooth Muscle Tumors
Chapter 210: Low-Grade Endometrioid Stromal Sarcoma
Chapter 211: Benign and Malignant Vascular Tumors
GERM CELL TUMORS
Chapter 212: Mature Cystic Teratoma
Chapter 213: Struma Ovarii
Chapter 214: Strumal Carcinoid
Chapter 215: Carcinoid Tumor (Insular, Trabecular, and Mucinous)
Chapter 216: Secondary Tumors in Teratomas
Chapter 217: Immature Teratoma
Chapter 218: Primitive Neuroectodermal Tumor
Chapter 219: Dysgerminoma
Chapter 220: Yolk Sac Tumor
Chapter 221: Polyembryoma
Chapter 222: Nongestational Choriocarcinoma
MIXED GERM CELL-STROMAL TUMORS
Chapter 223: Gonadoblastoma
Chapter 224: Unclassified Mixed Germ Cell/Sex Cord-Stromal Tumor
MISCELLANEOUS PRIMARY TUMORS
Chapter 225: Malignant Mesothelioma
Chapter 226: Melanoma
Chapter 227: Lymphomas and Leukemias
METASTATIC/SECONDARY TUMORS
Chapter 228: Colorectal Carcinoma
Chapter 229: Gastric Carcinoma
Chapter 230: Appendiceal Tumors
Chapter 231: Pancreaticobiliary Adenocarcinoma
Chapter 232: Lung Carcinoma
Chapter 233: Cervical Carcinoma
Chapter 234: Uterine Corpus Carcinoma
Chapter 235: Breast Carcinoma
Chapter 236: Melanoma
Chapter 237: Involvement by Gastrointestinal Stromal Tumor
SECTION 7: PERITONEUM
NONNEOPLASTIC LESIONS
Chapter 238: Benign Müllerian Lesions
Chapter 239: Florid Mesothelial Hyperplasia
Chapter 240: Peritoneal Inclusion Cysts
EPITHELIAL TUMORS
Chapter 241: Serous Borderline Tumor
Chapter 242: Serous Carcinoma
Chapter 243: Well-Differentiated Papillary Mesothelial Tumor
Chapter 244: Malignant Mesothelioma
Chapter 245: Pseudomyxoma Peritonei
MESENCHYMAL TUMORS
Chapter 246: Solitary Fibrous Tumor
Chapter 247: Disseminated Peritoneal Leiomyomatosis
Chapter 248: Extragastrointestinal Stromal Tumor
Chapter 249: Intraabdominal Desmoplastic Small Round Cell Tumor
INDEX

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Marisa R. Nucci

Esther Oliva