Dermatopathology
- 3rd Edition - November 25, 2024
- Authors: Klaus J. Busam, Pedram Gerami
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 8 3 0 7 1 - 3
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 3 0 7 2 - 0
Part of the popular Foundations in Diagnostic Pathology Series, Dermatopathology, Third Edition, is a practical and affordable resource that is ideal for study and review as well a… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quotePart of the popular Foundations in Diagnostic Pathology Series, Dermatopathology, Third Edition, is a practical and affordable resource that is ideal for study and review as well as everyday clinical practice. With its highly templated format, clearly written text, and concise summary tables, this user-friendly reference helps both trainees and practicing pathologists accurately diagnose specimens, avoid pitfalls, and confidently sign out pathology reports on these often difficult and challenging cases.
- Covers a wide range of neoplastic and non-neoplastic disorders of the skin, with detailed discussions of metabolic, systemic, allergic, infectious, and inflammatory skin diseases and cutaneous neoplasms
- Offers a superb overview of key diagnoses in dermatopathology using a full-color format with integrated images that facilitate quick and easy retrieval of key facts
- Presents each pathologic entity's gross and microscopic features, prognostic and therapeutic considerations, ancillary studies, and differential diagnoses
- Includes up-to-date information on IHC staining techniques, molecular genetic techniques and diagnostic tests, ancillary tools, and dermatologic disorders in an easy-to-use format that’s perfect for exam prep and clinical application
- Features more than 1,000 color histopathologic and clinical images that demonstrate key features of pathologic lesions, helping readers recognize the huge variety of appearances that cutaneous biopsy samples can present
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date
Residents and practitioners in Pathology; Residents and practitioners in Dermatology; Fellows in Dermatopathology
- Dermatopathology : A Volume in the Series Foundations in Diagnostic Pathology
- Cover image
- Title page
- Table of Contents
- Other books in this series
- Copyright
- Dedication
- Contributors
- Preface
- List of Illustrations
- List of Tables
- Section 1. Non-Neoplastic Disorders
- 1. Inflammatory diseases of the dermis and epidermis
- Spongiotic dermatitis
- Miscellaneous inflammatory disorders
- ■ Folliculitis
- Suggested further reading
- 2. Panniculitis
- ■ Vasculitis involving the subcutis
- ■ Panniculitis without vasculitis
- ■ Mostly septal panniculitis
- ■ Mostly lobular panniculitis
- ■ Acknowledgment
- Suggested further reading
- 3. Infectious diseases of the skin
- Viral infections
- ■ Human papilloma virus
- ■ Herpesvirus family
- Infections by other members of the herpesvirus family
- ■ Pox virus family
- ■ Miscellaneous viral exanthems
- Bacterial infections
- ■ Mycobacterial infections
- ■ Treponemal infections
- ■ Nonvenereal treponemal infections—yaws, bejel, and pinta
- Fungal infections
- ■ Superficial fungal infections
- ■ Superficial and deep fungal infections
- Protozoan disease, parasitic infestations, algal infections, and bites
- ■ Acknowledgments
- Suggested further reading
- 4. Cutaneous vasculitis
- Vasculitides affecting predominantly small vessels
- Vasculitides affecting small- to medium-sized vessels
- ■ Granulomatosis with polyangiitis, eosinophilic granulomatosis with polyangiitis, and microscopic polyangiitis
- Vasculitides affecting predominantly medium-sized vessels
- Vasculitides affecting predominantly larger vessels
- Other miscellaneous vasculitides
- ■ Acknowledgment and appreciation
- Suggested further reading
- 5. Blistering skin diseases
- Approach to the diagnosis of blistering diseases
- Intraepithelial blisters
- ■ Intracorneal and granular layer blisters
- ■ Intraepidermal blister with spongiosis or edema
- ■ Intraepidermal blister with acantholysis
- Subepidermal blisters
- ■ Subepidermal blister with neutrophils or eosinophils
- ■ Subepidermal vesicle with no or only minimal inflammation
- ■ Miscellaneous other intra- or subepidermal blisters
- ■ Acknowledgment
- Suggested further reading
- 6. Mucinoses, deposition disorders, and connective tissue alterations
- Cutaneous mucinoses
- Deposition disorders
- ■ Hyaline deposits
- ■ Colloid milium
- ■ Calcium, osseous, and cartilaginous deposits
- ■ Cartilaginous deposits
- ■ Pigmentary deposits
- Fillers and implants
- Alterations of dermal connective tissue
- Suggested further reading
- 7. Nonneoplastic disorders of pigmentation
- Café-au-lait macules
- ■ Disorders of decreased pigmentation
- Suggested further reading
- 8. Alopecia
- Introduction
- Biopsy collection and processing
- Normal hair follicle anatomy and growth cycles
- An algorithmic approach to diagnosis, with pattern clusters and critical first questions
- Cicatricial alopecia overview (patterns 1–5)
- “Biphasic” alopecias (pattern 6)
- Noncicatricial alopecia overview (patterns 8–11)
- Nonconforming patterns
- ■ Acknowledgments
- Suggested further reading
- 9. Cysts and sinuses
- Cysts derived from appendageal structures
- ■ Cysts arising from the infundibular portion of the hair follicle
- ■ Cysts arising from the isthmus portion of the hair follicle
- ■ Cysts arising from the sebaceous duct
- ■ Cysts arising from the eccrine duct
- ■ Cysts arising from the apocrine duct or gland
- ■ Developmental cysts
- ■ Pseudocysts
- ■ Pits and sinuses
- Suggested further reading
- 10. Pediatric dermatopathology
- Introduction
- Disorders of newborns and infants
- Hereditary disorders of cornification
- Bullous disorders of childhood
- Inflammatory skin conditions in the pediatric population
- ■ Spongiotic and/or psoriasiform dermatitis
- ■ Interface/lichenoid dermatitis
- ■ Prognosis and treatment
- ■ Papulosquamous conditions in children
- ■ Predominantly perivascular dermatoses
- Infectious diseases with skin manifestations
- ■ Viral exanthems of childhood
- ■ Exanthems of childhood related to bacterial infections
- Miscellaneous other disorders
- ■ Vasocclusive and vasculitic conditions
- ■ Deposition and sclerosing disorders
- ■ Disorders of collagen and elastic tissue
- ■ Vascular anomalies
- Suggested further reading
- Section 2. Tumors of the Skin and Subcutis
- 11. Tumors of the epidermis
- Benign tumors and tumor-like proliferations of the epidermis
- ■ Benign acanthomas and keratoses
- Intraepidermal squamous “precursor” lesions: Keratinocytic “dysplasias” and squamous cell carcinoma in situ (noninvasive carcinoma)
- Invasive squamous cell carcinoma
- Suggested further reading
- 12. Adnexal tumors
- Tumors with follicular differentiation
- ■ Follicular hamartoma (follicular nevus)
- ■ Nevus comedonicus
- ■ Benign follicular neoplasms
- Neoplasms with apocrine or eccrine differentiation
- ■ Hamartoma and nevus
- ■ Benign neoplasms
- Sebaceous neoplasms
- ■ Adnexal carcinomas
- ■ Adnexal neoplasms associated with systemic syndromes
- Suggested further reading
- 13. Melanocytic neoplasms
- Lentigines and lentigo-like lesions
- Melanocytic nevi
- Miscellaneous other melanocytic nevi
- Primary melanoma
- Common (conventional) variants of melanoma
- Uncommon pathologic variants of melanoma
- Rare melanomas with peculiar microscopic features
- Metastatic melanoma
- Pathology reporting of melanoma
- Prognosis
- Surgical management
- Suggested further reading
- 14. Soft tissue tumors
- Tumor-like reactions that mimic cutaneous mesenchymal tumors
- Reactive vascular proliferations
- Fibroblastic and myofibroblastic tumors
- Myofibroblastic tumors with USP6 gene rearrangement
- Select gene fusion-driven fibroblastic neoplasms with predilection for skin and subcutis
- Benign fibrohistiocytic or histiocytoid tumors
- Locally aggressive and malignant fibroblastic/myofibroblastic tumors
- Malignant fibroblastic and myofibroblastic tumors
- Lipomatous tumors
- ■ Benign tumors
- Benign lipomatous tumors with RB1 deletion
- Locally aggressive and malignant lipomatous tumors
- Myogenic tumors
- ■ Benign neoplasms
- Malignant neoplasms
- Nerve sheath tumors and tumor-like reactions
- ■ Benign lesions
- Malignant neoplasms
- Soft tissue neoplasms with melanocytic differentiation
- Miscellaneous sarcomas of uncertain differentiation
- Select undifferentiated round cell sarcomas
- Cutaneous vascular tumors
- Hemangiomas with GNAQ/GNA11 mutations
- Other angioma subtypes
- Locally aggressive and malignant vascular tumors
- Tumors with calcifications, osseous, and cartilaginous differentiation
- Cutaneous manifestations of malignant matrix-forming neoplasms
- Suggested further reading
- 15. Hematopoietic neoplasms
- Cutaneous lymphomas and benign mimics
- ■ Cutaneous T-cell lymphoma
- ■ Primary cutaneous T-cell lymphoma
- ■ Secondary T-cell lymphoma (extracutaneous T-cell lymphoma involving skin)
- ■ Cutaneous T-cell pseudolymphoma
- ■ Cutaneous B-cell lymphoma
- ■ Indolent variants of primary cutaneous B-cell lymphoma
- ■ Aggressive variants of cutaneous B-cell lymphoma
- ■ Miscellaneous other B-cell lymphomas affecting the skin
- Infiltration of the skin by hematopoietic stem cell and plasmacytoid dendritic cell neoplasms
- Mast cell infiltrates
- ■ Mastocytosis
- ■ Acknowledgment
- Suggested further reading
- 16. Histiocytoses
- ■ L Group histiocytoses
- ■ C Group of histiocytes
- Suggested further reading
- 17. Cutaneous neuroendocrine (Merkel cell) carcinoma
- Merkel cell carcinoma
- ■ Acknowledgment
- Suggested further reading
- 18. Metastatic tumors involving the skin
- Suggested further reading
- Section 3. Pathology of Special Sites
- 19. Neoplastic and nonneoplastic disorders of the nail apparatus
- ■ Anatomy of the nail unit
- ■ Inflammatory and keratotic diseases of the nail unit
- ■ Neoplasms affecting the nail unit
- ■ Epithelial neoplasms and hyperplasia
- ■ Distinctive tumors of the nail unit
- ■ Fibrous and soft tissue neoplasms more common in the nail unit
- ■ Vascular neoplasms
- Suggested further reading
- 20. Neoplastic and nonneoplastic disorders of the conjunctiva and eyelid
- Nonneoplastic disorders
- ■ Inflammatory lesions
- ■ Noninflammatory lesions
- Neoplasms
- ■ Squamous lesions
- ■ Melanocytic lesions
- ■ Hematolymphoid neoplasms
- ■ Glandular lesions
- Suggested further reading
- Index
- No. of pages: 870
- Language: English
- Edition: 3
- Published: November 25, 2024
- Imprint: Elsevier
- Hardback ISBN: 9780323830713
- eBook ISBN: 9780323830720
KB
Klaus J. Busam
Dr. Klaus Busam is a Professor of Pathology at Memorial Sloan Kettering Cancer Center and the Director of the combined Memorial Sloan Kettering/Cornell Dermatopathology Training Program. His training is from the Brigham & Women’s Hospital and Harvard Medical School combined program. His interests include the utilization of clinical, histological and molecular diagnostic methods to optimize diagnostic accuracy and best predict the behavior of melanocytic neoplasms. As a dermatopathologist, he is recognized as an international expert in the diagnosis of melanoma and is sent many second opinion cases both from within and outside of the United States. As a researcher he is focused on developing molecular based methods to improve the diagnosis and prognostication of melanocytic neoplasms. He has authored over 250 peer reviewed journal articles and numerous textbooks in dermatopathology.
Affiliations and expertise
Director of Dermatopathology, Department of Pathology, Memorial Sloan Kettering Cancer Center; Professor, Department of Pathology and Laboratory Medicine, Cornell University, New York, New YorkPG
Pedram Gerami
Dr Pedram Gerami: Selected to Best Doctors in America 2019-2020, Dr Gerami is the director of the Skin Cancer Institute of Northwestern Medical Group (SCIN-Med) and the director of the Melanoma Program in the Skin Cancer Institute and the Melanoma clinic in the department of Dermatology. His clinical and research interests are primarily focused on melanoma skin cancer, atypical nevi and borderline melanocytic tumors such as Spitz tumors which may be difficult to classify. As a dermatologist, dermatopathologist and researcher focused in the care of patients with melanoma and atypical nevi, he has a unique perspective on the behavior of melanocytic neoplasms.
Affiliations and expertise
Professor of Dermatology, Department of Dermatology, Pediatrics and Pathology, Northwestern University Feinberg School of Medicine, Chicago, Illinois