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Cytodifferentiation and Macromolecular Synthesis
- 1st Edition - November 14, 2012
- Editor: Michael Locke
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 4 3 3 4 4 4 - 1
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 5 7 5 6 - 8
Cytodifferentiation and Macromolecular Synthesis focuses on research on biosynthesis, structure, and morphology of cells. The book first discusses cytodifferentiation and… Read more
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Request a sales quoteCytodifferentiation and Macromolecular Synthesis focuses on research on biosynthesis, structure, and morphology of cells. The book first discusses cytodifferentiation and macromolecular synthesis and genetic control of protein structure. The relationship of amino acid substitutions to the genetic code; comparison of gene and protein alterations; and suppressor mutations are described. The text also looks at genetic repression, allosteric inhibition, and cellular differentiation; epigenetic control of protein synthesis in cells; quantitative studies of protein synthesis in embryonic tissues; and chromosomes and cytodifferentiation. The book also discusses the morphological and chemical differentiation of plastids. The effect of light on plastid development; structure of mature chloroplast; morphological changes in the development of proplastid to the chloroplast; and inheritable factors that control plastids are described. The text also focuses on the collagen system, mechanisms of elongation, and tissue interaction and metabolic responses. The book is a valuable reference for readers wanting to conduct research on the complex nature of cells.
List of Contributors
Foreword
Cytodifferentiation and Macromolecular Synthesis
Genetic Control of Protein Structure
Characteristics of the Gene-Protein System Selected for Study
Comparison of Gene Alterations and Protein Alterations
The Relationship of Amino Acid Substitutions to the Genetic Code
Suppressor Mutations—Alterations of the Translation Mechanism
Genetic Repression, Allosteric Inhibition, and Cellular Differentiation
Introduction
Regulation of Enzymatic Activity: Allosteric Effects
Regulation of Protein Synthesis in Bacteria
Negative Regulation Controlled by Specific Genetic Determinants
Operators and Polygenic Operons
Messenger RNA and Regulation at the Genetic Level
The Repressor
Genetic Regulation and Differentiation
Model Circuits
Conclusion
Epigenetic Control of Specific Protein Synthesis in Differentiating Cells
Isozymes
Physicochemical Nature of LDH
Subunit Hypothesis
Chemical Composition
Immunochemical Properties
Function of Isozymes
Quantitative Studies of Protein Synthesis in Some Embryonic Tissues
Protein Synthesis in the Explanted Chick Embryo
Protein Synthesis in Differentiating Tissues during Late Development
Chromosomes and CytodifFerentiation
Structural Considerations
Loops, Puffs, and Genes
Heterogeneity of Nuclear RNA
RNA Synthesis in Lampbrush Chromosome Loops
Control of Chromosomal Synthesis
Discussion
Concluding Remarks
The Plastids: Their Morphological and Chemical Differentiation
Introduction
Structure of the Mature Chloroplast
Relation of Chloroplast Structure to Photosynthetic Function
Morphological Changes in the Development of the Proplastid to the Chloroplast
The Effect of Light on Plastid Development
Chlorophyll Biosynthesis in the Developing Plastid
Inheritable Factors That Control the Plastids
Cytoplasmic Inheritance of Euglena Plastids
Origin of Plastid Types
Summary
Organization and Disorganization of Extracellular Substances: The Collagen System
Organization of Collagen
Experimental Lathyrism
Collagen Degradation in Animal Tissues
On Mechanisms of Elongation
Axis Extension Related to Ordered Synthesis of Cell Wall
Significance of Transverse Wall Texture in Elongation in Nitella
Polarized Light Microscopy
Peculiar Optical Properties of Elongating Cell Walls
Evidence for a Cytoplasmic Framework
The Cytoplasmic Framework—Its Action in Orienting Synthesis
Influences on the Orientation of the Cytoplasmic Framework
Role of Strain in the Orientation of the Cytoplasmic Framework
Nature of the Rectifying Mechanism
A Provisional Model
Discussion
Summary
Tissue Interaction and Specific Metabolic Responses: Chondrogenic Induction and Differentiation
Experimental Modification of Degrees of Differentiation Manifested by Tissue Dissociation and Short-Term Re-aggregation
An Apparently Anomalous Instance of Chondrogenesis in Explants of Embryonic Mesonephros
A More Detailed Account of the Interactions Involved in the Induction of Vertebral Cartilage
Discussion
Author Index
Subject Index
- No. of pages: 286
- Language: English
- Edition: 1
- Published: November 14, 2012
- Imprint: Academic Press
- Paperback ISBN: 9780124334441
- eBook ISBN: 9780323157568